2012

Dondelinger, F., Rogers, S., Filippone, M., Cretella, R., Palmer, T., Smith, R., Millar, A., and Husmeier, D. (2012) Parameter inference in mechanistic models of cellular regulation and signalling pathways using gradient matching. In: WCSB2012 - 9th International Workshop on Computational Systems Biology, 4-6 Jun 2012, Ulm, Germany.

Parnell, E., Smith, B.O., Palmer, T.M., Terrin, A., Zaccolo, M., and Yarwood, S.J. (2012) Regulation of the inflammatory response of vascular endothelial cells by EPAC1. British Journal of Pharmacology, 166 (2). pp. 434-446. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2011.01808.x)

Milne, G.R., Palmer, T.M., and Yarwood, S.J. (2012) Novel control of cAMP-regulated transcription in vascular endothelial cells. Biochemical Society Transactions, 40 (1). pp. 1-5. ISSN 0300-5127 (doi:10.1042/BST20110606)

Salt, I.P., and Palmer, T.M. (2012) Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation. Expert Opinion on Investigational Drugs, 21 (8). pp. 1155-1167. ISSN 1354-3784 (doi:10.1517/13543784.2012.696609)

Sands, W.A., Woolson, H.D., Yarwood, S.J., and Palmer, T.M. (2012) Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter. Methods in Molecular Biology, 809 . pp. 201-214. ISSN 1064-3745 (doi:10.1007/978-1-61779-376-9_14)

Williams, J.J.L., and Palmer, T.M. (2012) Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3. Biochemical Society Transactions, 40 (1). pp. 215-218. ISSN 0300-5127 (doi:10.1042/BST20110629)

2011

Lawlor, D.A., Fraser, A., Macdonald-Wallis, C., Nelson, S.M., Palmer, T.M., Davey Smith, G., and Tilling, K. (2011) Maternal and offspring adiposity-related genetic variants and gestational weight gain. American Journal of Clinical Nutrition, 94 (1). pp. 149-155. ISSN 0002-9165 (doi:10.3945/ajcn.110.010751)

Milne, G.R., and Palmer, T.M. (2011) Anti-inflammatory and immunosuppressive effects of the A2A adenosine receptor. Scientific World Journal, 11 . pp. 320-39. ISSN 1537-744X (doi:10.1100/tsw.2011.22)

Milne, G.R., and Palmer, T.M. (2011) Novel control of cAMP-regulated transcription in vascular endothelial cells. Scientific World Journal, 11 . pp. 320-339. ISSN 1537-744X (doi:10.1100/tsw.2011.22)

2010

Safhi, M.M.A., Rutherford, C., Ledent, C., Sands, W.A., and Palmer, T.M. (2010) Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the a2a adenosine receptor. Molecular Pharmacology, 77 (6). pp. 968-978. ISSN 0026-895X (doi:10.1124/mol.109.062455)

Mundell , S.J., Matharu, A.-L., Palmer, T.M., Benovic, J.L., and Kelly, E. (2010) Deletion of the distal COOH-terminus of the A_2B adenosine receptor switches agonist-induced internalisation to an arrestin- and clathrin-independent pathway and inhibits receptor recycling. British Journal of Pharmacology, 159 (3). pp. 518-533. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2009.00598.x)

Rutherford, C., and Palmer, T.M. (2010) Molecular basis of protective anti-inflammatory signalling by cyclic AMP in the vascular endothelium. In: Choi, S. (ed.) Systems Biology of Signaling Networks. Series: Systems biology (1). Springer, pp. 561-588. ISBN 9781441957962

2009

Woolson, H.D., Thomson, V.S., Rutherford, C., Yarwood, S.J., and Palmer, T.M. (2009) Selective inhibition of cytokine-activated extracellular signal-regulated kinase by cyclic amp via Epac1-dependent induction of suppressor of cytokine signalling-3. Cellular Signalling, 21 (11). pp. 1706-1715. ISSN 0898-6568 (doi:10.1016/j.cellsig.2009.07.009)

Borland, G., Bird, R. J., Palmer, T.M., and Yarwood, S.J. (2009) Activation of Protein Kinase C  by EPAC1 Is Required for the ERK- and CCAAT/Enhancer-binding Protein  -dependent Induction of the SOCS-3 Gene by Cyclic AMP in COS1 Cells. Journal of Biological Chemistry, 284 (26). pp. 17391-17403. ISSN 0021-9258 (doi:10.1074/jbc.M109.015370)

Mair, K.M., MacLean, M.R., Morecroft, I., Dempsie, Y., and Palmer, T.M. (2009) Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts. British Journal of Pharmacology, 155 (4). pp. 606-616. ISSN 0007-1188 (doi:10.1038/bjp.2008.310)

Mair, K.M., MacLean, M.R., Morecroft, I., Dempsie, Y., and Palmer, T.M. (2009) Novel interactions between the 5-HT transporter, 5-HT_1B receptors and Rho kinase in vivo and in pulmonary fibroblasts. British Journal of Pharmacology, 155 (4). pp. 606-616. ISSN 0007-1188 (doi:10.1038/bjp.2008.310)

Palmer, T.M., and Trevethick, M.A. (2009) Suppression of inflammatory and immune responses by the A2A adenosine receptor: an introduction. British Journal of Pharmacology, 153 (S1). S27-S34. ISSN 0007-1188 (doi:10.1038/sj.bjp.0707524)

2008

Sands, W.A., and Palmer, T.M. (2008) Regulating gene transcription in response to cyclic AMP elevation. Cellular Signalling, 20 (3). pp. 460-466. ISSN 0898-6568 (doi:10.1016/j.cellsig.2007.10.005)

Yarwood, S.J., Borland, G., Sands, W.A., and Palmer, T.M. (2008) Identification of CCAAT/Enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. Journal of Biological Chemistry, 283 (11). pp. 6843-6853. ISSN 0021-9258 (doi:10.1074/jbc.M710342200)

2007

Palmer, T.M., and Trevethick, M.A. (2007) Suppression of inflammatory and immune responses by the A(2A) adenosine receptor: an introduction. British Journal of Pharmacology, 153 . S27-S34. ISSN 0007-1188 (doi:10.1038/sj.bjp.0707524)

2006

Sands, W.A., Woolson, H.D., Milne, G.R., Rutherford, C., and Palmer, T.M. (2006) Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells. Molecular and Cellular Biology, 26 (17). pp. 6333-6346.

Funakoshi, H et al. (2006) Regulated overexpression of the A(1)-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function. Circulation, 114 . pp. 2240-2250. (doi:10.1161/CIRCULATIONAHA.106.620211)

2005

Rutherford, C, Ord-Shrimpton, FU, Sands, WA, Pediani, JD, Benovic, JL, McGrath, JC, and Palmer, TM (2005) Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P(3). Cellular Signalling, 17 . pp. 997-1009. (doi:10.1016/j.cellsig.2004.11.018)

Sands, WA, and Palmer, TM (2005) Adenosine receptors and the control of endothelial cell function in inflammatory disease. Immunology Letters, 101 . pp. 1-11. (doi:10.1016/j.imlet.2005.04.005)

Sands, WA, and Palmer, TM (2005) Inhibition of pro-inflammatory cytokine receptor signalling by CAMP in vascular endothelial cells. Biochemical Society Transactions, 33 . pp. 1126-1128.

2004

Sands, WA, Martin, AF, Strong, EW, and Palmer, TM (2004) Specific inhibition of nuclear factor-kappa B-dependent inflammatory responses by cell type-specific mechanisms upon A(2A) adenosine receptor gene transfer. Molecular Pharmacology, 66 . pp. 1147-1159. (doi:10.1124/mol.104.001107)

2003

Palmer, TA, Ferguson, G, and Watterson, KR (2003) Dissecting the regulatory mechanisms controlling inhibitory adenosine receptor signaling. Drug Development Research, 58 . pp. 302-314. (doi:10.1002/ddr.10185)

Perry, CG, Palmer, T, Cleland, SJ, Morton, IJ, Salt, IP, Petrie, JR, Gould, GW, and Connell, JMC (2003) Decreased insulin sensitivity during dietary sodium restriction is not mediated by effects of angiotensin II on insulin action. Clinical Science, 105 (2). pp. 187-194. ISSN 0143-5221 (doi:10.1042/CS20020320)

2002

Ferguson, G, Watterson, KR, and Palmer, TM (2002) Subtype-specific regulation of receptor internalization and recycling by the carboxyl-terminal domains of the human A(1) and rat A(3) adenosine receptors: Consequences for agonist-stimulated translocation of arrestin3. Biochemistry, 41 . pp. 14748-14761. (doi:10.1021/bi0262911)

Klinger, M, Kuhn, M, Just, H, Stefan, E, Palmer, T, Freissmuth, M, and Nanoff, C (2002) Removal of the carboxy terminus of the A(2A)-adenosine receptor blunts constitutive activity: differential effect on cAMP accumulation and MAP kinase stimulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 366 . pp. 287-298. ISSN 0028-1298 (doi:10.1007/s00210-002-0617-z)

Palmer, T (2002) Molecular regulation of adenosine receptor signalling: implications for the design of novel cardioprotective and anti-inflammatory therapies. Recent Research Developments in Molecular Pharmacology, 1 . pp. 53-75.

Watterson, KR, Johnston, E, Chalmers, C, Pronin, A, Cook, SJ, Benovic, JL, and Palmer, TM (2002) Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2. Journal of Biological Chemistry, 277 . pp. 5767-5777. ISSN 0021-9258 (doi:10.1074/jbc.M110647200)

2001

Alderton, F., Rakhit, S., Kong, K.C., Palmer, T., Sambi, B., Pyne, S., and Pyne, N.J. (2001) Tethering of the platelet-derived growth factor ß receptor to G-protein-coupled receptors - A novel platform for integrative signaling by these receptor classes in mammalian cells. Journal of Biological Chemistry, 276 . pp. 28578-28585. ISSN 0021-9258 (doi:10.1074/jbc.M102771200 )