2013

Kennedy, S., Wu, J., Wadsworth, R.M., Lawrence, C.E., and Maffia, P. (2013) Mast cells and vascular diseases. Pharmacology and Therapeutics, 138 (1). pp. 53-65. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2013.01.001)

Watt, J., Kennedy, S., McCormick, C., Agbani, E.O., McPhaden, A., Mullen, A., Czudaj, P., Behnisch, B., Wadsworth, R.M., and Oldroyd, K.G. (2013) Succinobucol-eluting stents increase neointimal thickening and peri-strut inflammation in a porcine coronary model. Catheterization and Cardiovascular Interventions, 81 (4). pp. 698-708. ISSN 1522-1946 (doi:10.1002/ccd.24473)

Ewart, M-A., and Kennedy, S. (2013) Diabetic cardiovascular disease AMP-activated protein kinase (AMPK) as a therapeutic target. Cardiovascular and Hematological Agents in Medicinal Chemistry . ISSN 1871-5257 (In Press)

McDonald, R.A. et al. (2013) miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation. European Heart Journal . ISSN 0195-668X (doi:10.1093/eurheartj/eht105) (In Press)

2012

Greig, F.H., Kennedy, S., and Spickett, C.M. (2012) Physiological effects of oxidized phospholipids and their cellular signaling mechanisms in inflammation. Free Radical Biology and Medicine, 52 (2). pp. 266-280. ISSN 0891-5849 (doi:10.1016/j.freeradbiomed.2011.10.481)

Watt, J., Ewart, M-A., Greig, F.H., Oldroyd, K., Wadsworth, R.M., and Kennedy, S. (2012) The effect of reactive oxygen species on whole blood aggregation and the endothelial cell-platelet interaction in patients with coronary heart disease. Thrombosis Research, 130 (2). pp. 210-215. ISSN 0049-3848 (doi:10.1016/j.thromres.2012.03.024)

Watt, J., Ewart, M., Greig, F.H., Oldroyd, K.G., Wadsworth, R.M., and Kennedy, S. (2012) The effect of reactive oxygen species on whole blood aggregation and the enothelial cell-platelet interaction in patients with coronary heart disease. Thrombosis Research, 130 (2). pp. 210-215. ISSN 0049-3848 (doi:10.1016/j.thromres.2012.03.024)

2011

Ialenti, A. et al. (2011) Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries. Arteriosclerosis, Thrombosis and Vascular Biology, 31 (11). pp. 2448-2454. ISSN 1079-5642 (doi:10.1161/ATVBAHA.111.230078)

Ewart, M.-A., and Kennedy, S. (2011) AMPK and vasculoprotection. Pharmacology and Therapeutics, 131 (2). pp. 242-253. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2010.11.002)

Wu, J., Wadsworth, R.M., and Kennedy, S. (2011) Inhibition of inducible Nitric Oxide synthase promotes vein graft neoadventitial inflammation and remodelling. Journal of Vascular Research, 48 (2). pp. 141-149. ISSN 1018-1172 (doi:10.1159/000316968)

2010

Grassia, G. et al. (2010) The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation. Arteriosclerosis, Thrombosis and Vascular Biology , 30 (12). pp. 2458-2466. ISSN 1079-5642 (doi:10.1161/ATVBAHA.110.215467)

Guglielmotti, A., Grassia, G., Gordon, P., Maddaluno, M., Di Lauro, M.V., Biondi, G., Colombo, A., Ialenti, A., Maffia, P., and Kennedy, S. (2010) Bindarit, an inhibitor of monocyte chemoattractant proteins (MCPs) production, reduces in-stent restenosis in porcine coronary arteries. In: American Heart Association Scientific Session 2010, 13-17 Nov 2010, Chicago, IL.

McCormick, C., Jones, R.L., Kennedy, S., and Wadsworth, R.M. (2010) Activation of prostanoid EP receptors by prostacyclin analogues in rabbit iliac artery: Implications for anti-restenotic potential. European Journal of Pharmacology, 641 (2-3). pp. 160-167. ISSN 0014-2999 (doi:10.1016/j.ejphar.2010.04.035)

Mair, K.M., Robinson, E., Kane, K.A., Pyne, S., Brett, R.R., Pyne, N.J., and Kennedy, S. (2010) Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery. British Journal of Pharmacology, 161 (1). pp. 176-192. ISSN 1476-5381 (doi:10.1111/j.1476-5381.2010.00878.x)

Shedden, L., Kennedy, S., Wadsworth, R., and Connolly, P. (2010) Towards a self-reporting coronary artery stent—Measuring neointimal growth associated with in-stent restenosis using electrical impedance techniques. Biosensors and Bioelectronics, 26 (2). pp. 661-666. ISSN 0956-5663 (doi:10.1016/j.bios.2010.06.073)

Shedden, L., Kennedy, S., Wadsworth, R., and Connolly, P. (2010) Towards a self-reporting coronary artery stent—Measuring neointimal growth associated with in-stent restenosis using electrical impedance techniques. Biosensors and Bioelectronics, 26 (2). pp. 661-666. ISSN 0956-5663 (doi:10.1016/j.bios.2010.06.073)

2009

Lim, S.Y., Wainwright, C.L., Kennedy, S., and Kane, K.A. (2009) Activation of protease activated receptor-2 induces delayed cardioprotection in anesthetized mice. Cardiovascular Drugs and Therapy, 23 (6). pp. 519-520. ISSN 0920-3206 (doi:10.1007/s10557-007-6073-8)

Farmer, D.G.S., and Kennedy, S. (2009) RAGE, vascular tone and vascular disease. Pharmacology and Therapeutics, 124 (2). pp. 185-194. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2009.06.013)

Kennedy, S., Kane, K.A., Pyne, N.J., and Pyne, S. (2009) Targeting sphingosine-1-phosphate signalling for cardioprotection. Current Opinion in Pharmacology, 9 (2). pp. 194-201. ISSN 1471-4892 (doi:10.1016/j.coph.2008.11.002)

2008

Dever, G.J., Benson, R., Wainwright, C.L., Kennedy, S., and Spickett, C.M. (2008) Phospholipid chlorohydrin induces leukocyte adhesion to ApoE^-/-mouse arteries via upregulation of P-Selectic. Free Radical Biology and Medicine, 44 (3). pp. 452-463. ISSN 0891-5849 (doi:10.1016/j.freeradbiomed.2007.10.038)

Erridge, C., Kennedy, S., Spickett, C.M., and Webb, D.J. (2008) Oxidised phospholipid inhibition of toll-like receptor (TLR) signalling is restricted to TLR2 and TLR4 - roles for CD14, LPS-binding protein and MD2 as targets for specificity of inhibition. Journal of Biological Chemistry, 283 (36). pp. 24748-24759. ISSN 0021-9258 (doi:10.1074/jbc.M800352200)

Watt, J., Wadsworth, R., Kennedy, S., and Oldroyd, K. (2008) Pro-healing drug-eluting stents: a role for antioxidants? Clinical Science, 114 (4). pp. 265-273. ISSN 1470-8736 (doi:10.1042/CS20070207)

2007

Dever, G, Spickett, C.M., Kennedy, S., Rush, C., Tennant, G., Monopoli, A., and Wainwright, C.L. (2007) The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1α(βS*,δS*), 2α ,6α,8 β-(R*),8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy) butyl Ester)], Reduces Splenocyte Adhesion and Reactive Oxygen Species Generation in Normal and Atherosclerotic Mice. Journal of Pharmacology and Experimental Therapeutics, 320 (1). pp. 419-426. ISSN 0022-3565 (doi:10.1124/jpet.106.109298)

Coats, P., Kennedy, S., Pynea, S., Wainwright, C.L., and Wadsworth, R.M. (2007) Inhibition of non-Ras protein farnesylation reduces in-stent restenosis. Atherosclerosis, 197 (2). pp. 515-523. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2007.06.007)

Dever, G., Wainwright, C.L., Kennedy, S., and Spickett, C.M. (2007) Fatty acid and phospholipid chlorohydrins cause cell stress and endothelial adhesion. Acta Biochimica Polonica, 53 (4). pp. 761-768.

Kennedy, S., Burke, S.G., Preston, A.A., and McPhaden, A.R. (2007) Nitric oxide generation by NO donors is enhanced following balloon injury in the porcine coronary artery. Endothelium: Journal of Endothelial Cell Research, 14 . pp. 105-113.

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115 (11). E326-E328.

McCormick, C., Wadsworth, R.M., Jones, R.L., and Kennedy, S. (2007) Prostacyclin analogues: the next drug-eluting stent? Biochemical Society Transactions, 35 (5). pp. 910-911. (doi:10.1042/BST0350910)

Tennant, G.M., Wadsworth, R.M., and Kennedy, S. (2007) PAR-2 mediates increased inflammatory cell adhesion and neointima formation following vascular injury in the mouse. Atherosclerosis, 198 (1). pp. 57-64. ISSN 0021-9150

2006

Kennedy, S., Wadsworth, R.M., and Wainwright, C.L. (2006) Locally administered antiproliferative drugs inhibit hypercontractility to serotonin in balloon-injured pig coronary artery. Vascular Pharmacology, 44 . pp. 363-371. (doi:10.1016/j.vph.2006.01.012)

Lim, S.Y., Tennant, G.M., Kennedy, S., Wainwright, C.L., and Kane, K.A. (2006) Activation of mouse protease-activated receptor-2 induces lymphocyte adhesion and generation of reactive oxygen species. British Journal of Pharmacology, 149 . pp. 591-599. (doi:10.1038/sj.bjp.0706905)

2004

Kennedy, S, Preston, AA, McPhaden, AR, Miller, AM, Wainwright, CL, and Wadsworth, RM (2004) Correlation of changes in nitric oxide synthase, superoxide dismutase and nitrotyrosine with endothelial regeneration and neointimal hyperplasia in the balloon-injured rabbit subclavian artery. Coronary Artery Disease, 15 (6). pp. 337-346. (doi:10.1097/00019501-200409000-00007)

2003

Kennedy, S., Wadsworth, R.M., and Wainwright, C.L. (2003) Effect of antiproliferative agents on vascular function in nonnal and in vitro balloon-injured porcine coronary arteries. European Journal of Pharmacology, 481 (1). pp. 101-107. (doi:10.1016/j.ejphar.2003.09.010)

Kennedy, Simon, Fournet-Bourguignon, Marie-Pierre, Breugnot, Christine, Castedo-Delrieu, Maria, Lesage, Ludovic, Reure, Hélè, Briant, Cyril, Leonce, Stephane, Vilaine, Jean-Paul, and Vanhoutte, Paul M. (2003) Cells derived from regenerated endothelium of the porcine coronary artery contain more oxidized forms of apolipoprotein-B-100 without a modification in the uptake of oxidized LDL. Journal of Vascular Research, 40 (4). ISSN 1018-1172 (doi:10.1159/000072817)