Dr Scott Johnstone
- LKAS Research Fellow (Institute of Cardiovascular and Medical Sciences)
telephone: 01413302669
email: Scott.Johnstone@glasgow.ac.uk
Research:
Member:
Article
Straub, A., Lohman, A., Billaud, M., Johnstone, S., Dwyer, S., Lee, M., Schoppe-Bortz, P., Best, A., Gaston, B., and Isakson, B. (2012) Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. Nature, 491 (7424). pp. 473-477. ISSN 0028-0836 (doi:10.1038/nature11626)
Lohman, A.W., Billaud, M., Straub, A.C., Johnstone, S.R., Best, A.K., Lee, M., Barr, K., Penuela, S., Laird, D.W., and Isakson, B.E. (2012) Expression of pannexin isoforms in the systemic murine arterial network. Journal of Vascular Research, 49 (5). pp. 405-416. ISSN 1018-1172 (doi:10.1159/000338758)
Looft-Wilson, R.C., Billaud, M., Johnstone, S.R., Straub, A.C., and Isakson, B.E. (2012) Interaction between nitric oxide signaling and gap junctions: effects on vascular function. Biochimica et Biophysica Acta: BBA Biomembranes, 1818 (8). pp. 1895-1902. ISSN 0005-2736 (doi:10.1016/j.bbamem.2011.07.031)
Johnstone, S.R., Billaud, M., Lohman, A.W., Taddeo, E.P., and Isakson, B.E. (2012) Posttranslational modifications in connexins and pannexins. The Journal of Membrane Biology, 245 (5-6). pp. 319-332. ISSN 0022-2631 (doi:10.1007/s00232-012-9453-3)
Billard, M., Lohman, A.W., Sraub, A.C., Parpaite, T., Johnstone, S.R., and Isakson, B.E. (2012) Characterization of the thoracodorsal artery: morphology and reactivity. Microcirculation, 19 (4). pp. 360-372. ISSN 1073-9688 (doi:10.1111/j.1549-8719.2012.00172.x)
Billaud, M., Johnstone, S.R., and Isakson, B.E. (2012) Loss of compliance in small arteries, but not in conduit arteries, after 6 weeks exposure to high fat diet. Journal of Cardiovascular Translational Research, 5 (3). pp. 256-263. ISSN 1937-5387 (doi:10.1007/s12265-012-9354-y)
Johnstone, S.R. et al. (2012) MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. Circulation Research, 111 (2). pp. 201-211. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.112.272302)
Billaud, M. et al. (2011) Pannexin1 regulates 1-adrenergic receptor- mediated vasoconstriction. Circulation Research, 109 (1). pp. 80-85. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.110.237594)
Koval, M., Billaud, M., Straub, A.C., Johnstone, S.R., Zarbock, A., Duling, B.R., and Isakson, B.E. (2011) Spontaneous lung dysfunction and fibrosis in mice lacking connexin 40 and endothelial cell connexin 43. American Journal of Pathology, 178 (6). pp. 2536-2546. ISSN 0002-9440 (doi:10.1016/j.ajpath.2011.02.045)
Straub, A.C. et al. (2011) Compartmentalized connexin 43 S-Nitrosylation/Denitrosylation regulates heterocellular communication in the vessel wall. Arteriosclerosis, Thrombosis and Vascular Biology, 31 (2). pp. 399-407. ISSN 1079-5642 (doi:10.1161/ATVBAHA.110.215939)
Kadl, A. et al. (2010) Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circulation Research, 107 (6). pp. 737-746. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.109.215715)
Johnstone, S.R., Best, A.K., Wright, C.S., Isakson, B.E., Errington, R.J., and Martin, P.E. (2010) Enhanced connexin 43 expression delays intra-mitoitc duration and cell cycle traverse independently of gap junction channel function. Journal of Cellular Biochemistry, 110 (3). pp. 772-782. ISSN 0730-2312 (doi:10.1002/jcb.22590)
Straub, A.C., Johnstone, S.R., Heberlein, K.R., Rizzo, M.J., Best, A.K., Boitano, S., and Isakson, B.E. (2010) Site-specific connexin phosphorylation is associated with reduced heterocellular communication between smooth muscle and endothelium. Journal of Vascular Research, 47 (4). pp. 277-286. ISSN 1018-1172 (doi:10.1159/000265562)
Johnstone, S.R., Ross, J., Rizzo, M.J., Straub, A.C., Lampe, P.D., Leitinger, N., and Isakson, B.E. (2009) Oxidized phospholipid species promote in vivo differential Cx43 phosphorylation and vascular smooth muscle cell proliferation. American Journal of Pathology, 175 (2). pp. 916-924. ISSN 0002-9440 (doi:10.2353/ajpath.2009.090160)
Johnstone, S.R., Isakson, B., and Locke, D. (2009) Chapter 2 biological and biophysical properties of vascular connexin channels. International Review of Cell and Molecular Biology, 278 . pp. 69-118. ISSN 1937-6448 (doi:10.1016/S1937-6448(09)78002-5)
Book Section
Billaud, M., Johnstone, S.J., Heberlein, K., Straub, A., and Isakson, B. (2013) The effect of oxidative stress on connexins in the vasculature. In: Oviedo-Orta, E., Kwak, B.R. and Evans, W.H. (eds.) Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology. Taylor & Francis, Boca Raton, FL, USA. ISBN 9781439862575
