Dr Robert Mcdonald

  • Lecturer (Institute of Cardiovascular and Medical Sciences)

Research interests

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Role of non-coding RNA in vascular pathology
    British Heart Foundation
    2015 - 2019
     
  • VascmiR: miRNA in pathological vascular remodelling
    European Research Council
    2014 - 2019
     

Publications

List by: Type | Date

Jump to: 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2003
Number of items: 13.

2014

White, K. et al. (2014) Endothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3 axis. Hypertension, 64 (1). pp. 185-194. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.03037)

2013

McDonald, R. A. et al. (2013) miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation. European Heart Journal, 34 (22). pp. 1636-1643. ISSN 0195-668X (doi:10.1093/eurheartj/eht105)

White, K. M., Alba, R., Parker, A. L., Wright, A. F., Bradshaw, A. C., Delles, C., McDonald, R. A., and Baker, A. H. (2013) Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile. Journal of Cardiothoracic Surgery, 8 (183). ISSN 1749-8090 (doi:10.1186/1749-8090-8-183)

2012

Chick, H.E. et al. (2012) Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy, 23 (12). pp. 1247-1257. ISSN 1043-0342 (doi:10.1089/hum.2012.042)

Robertson, K.E., McDonald, R.A., Oldroyd, K.G., Nicklin, S.A., and Baker, A.H. (2012) Prevention of coronary in-stent restenosis and vein graft failure: Does vascular gene therapy have a role? Pharmacology and Therapeutics, 136 (1). pp. 23-34. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2012.07.002)

Caruso, P. et al. (2012) A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circulation Research, 111 (3). pp. 290-300. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.112.267591)

McDonald, R. A., Hata, A., MacLean, M. R., Morrell, N. W., and Baker, A. H. (2012) MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling. Cardiovascular Research, 93 (4). pp. 594-604. ISSN 0008-6363 (doi:10.1093/cvr/cvr299)

2011

George, S. J., Wan, S., Hu, J., McDonald, R.A., Johnson, J. L., and Baker, A.H. (2011) Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy. Circulation, 124 (11_sup). S135-S142. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.110.012732)

2010

Alba, R. et al. (2010) Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood, 14 (116). pp. 2656-2664. ISSN 0006-4971 (doi:10.1182/blood-2009-12-260026)

McDonald, R.A., Pyne, S., Pyne, N.J., Grant, A., Wainwright, C.L., and Wadsworth, R.M. (2010) The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia. British Journal of Pharmacology, 159 (3). pp. 543-553. ISSN 0007-1188 (doi:10.1111/J.1476-5381.2009.00533.x)

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6 (10). e1001177. ISSN 1553-7390 (doi:10.1371/journal.pgen.1001177)

2008

Checkland, K., Harrison, S., McDonald, R., Grant, S., Campbell, S., and Guthrie, B. (2008) Biomedicine, holism and general medical practice: responses to the 2004 general practitioner contract. Sociology of Health and Illness, 30 (5). pp. 788-803. ISSN 0141-9889 (doi:10.1111/j.1467-9566.2008.01081.x)

2003

Lloyd-Williams, F. et al. (2003) Why are patients in clinical trials of heart failure not like those we see in everyday practice? Journal of Clinical Epidemiology, 56 (12). pp. 1157-1162.

This list was generated on Thu Dec 18 00:42:35 2014 GMT.
Jump to: Articles
Number of items: 13.

Articles

White, K. et al. (2014) Endothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3 axis. Hypertension, 64 (1). pp. 185-194. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.113.03037)

McDonald, R. A. et al. (2013) miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation. European Heart Journal, 34 (22). pp. 1636-1643. ISSN 0195-668X (doi:10.1093/eurheartj/eht105)

White, K. M., Alba, R., Parker, A. L., Wright, A. F., Bradshaw, A. C., Delles, C., McDonald, R. A., and Baker, A. H. (2013) Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile. Journal of Cardiothoracic Surgery, 8 (183). ISSN 1749-8090 (doi:10.1186/1749-8090-8-183)

Chick, H.E. et al. (2012) Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy, 23 (12). pp. 1247-1257. ISSN 1043-0342 (doi:10.1089/hum.2012.042)

Robertson, K.E., McDonald, R.A., Oldroyd, K.G., Nicklin, S.A., and Baker, A.H. (2012) Prevention of coronary in-stent restenosis and vein graft failure: Does vascular gene therapy have a role? Pharmacology and Therapeutics, 136 (1). pp. 23-34. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2012.07.002)

Caruso, P. et al. (2012) A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circulation Research, 111 (3). pp. 290-300. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.112.267591)

McDonald, R. A., Hata, A., MacLean, M. R., Morrell, N. W., and Baker, A. H. (2012) MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling. Cardiovascular Research, 93 (4). pp. 594-604. ISSN 0008-6363 (doi:10.1093/cvr/cvr299)

George, S. J., Wan, S., Hu, J., McDonald, R.A., Johnson, J. L., and Baker, A.H. (2011) Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy. Circulation, 124 (11_sup). S135-S142. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.110.012732)

Alba, R. et al. (2010) Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood, 14 (116). pp. 2656-2664. ISSN 0006-4971 (doi:10.1182/blood-2009-12-260026)

McDonald, R.A., Pyne, S., Pyne, N.J., Grant, A., Wainwright, C.L., and Wadsworth, R.M. (2010) The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia. British Journal of Pharmacology, 159 (3). pp. 543-553. ISSN 0007-1188 (doi:10.1111/J.1476-5381.2009.00533.x)

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6 (10). e1001177. ISSN 1553-7390 (doi:10.1371/journal.pgen.1001177)

Checkland, K., Harrison, S., McDonald, R., Grant, S., Campbell, S., and Guthrie, B. (2008) Biomedicine, holism and general medical practice: responses to the 2004 general practitioner contract. Sociology of Health and Illness, 30 (5). pp. 788-803. ISSN 0141-9889 (doi:10.1111/j.1467-9566.2008.01081.x)

Lloyd-Williams, F. et al. (2003) Why are patients in clinical trials of heart failure not like those we see in everyday practice? Journal of Clinical Epidemiology, 56 (12). pp. 1157-1162.

This list was generated on Thu Dec 18 00:42:35 2014 GMT.