Dr Patrick Mark

  • Clinical Senior Lecturer (Institute of Cardiovascular and Medical Sciences)

telephone: 3308218
email: Patrick.Mark@glasgow.ac.uk


I am a Clinical Senior Lecturer and Honorary Consultant Nephrologist at the Glasgow Renal and Transplant Unit based at the Western Infirmary Glasgow. I graduated in Medicine in 1999 (MB ChB Honours 1996; Brunton Medal for first in year) and was awarded a PhD in 2008 (Bellahouston Medal for outstanding thesis by medical graduate).  

I was a British Heart Foundation Junior Clinical Fellow for the duration of my PhD thesis.  Following clinical training in Medicine and Nephrology combined with a Clinical Lecturer post; I was appointed as Clinical Senior Lecturer in 2011.  My major research interest is the cardiovascular complications of chronic kidney disease (CKD).  Current research themes and techniques are used to explore this field include:

  • Use of MRI studies to explore cardiac and renal dysfunction in hypertension and CKD
  • Epidemiological studies into early CKD and diabetes.  I am the UK lead for Syskid-PROVALID, a large EU study of risk factors for kidney disease in diabetes
  • Studies of dysregulation of the renin-angiotensin-aldosterone system in CKD
  • Clinical studies of oxidative stress in CKD
  • I am also the lead for the West of Scotland Academic Foundation Year program and am local principal investigator or co-investigator for a number of pharmaceutical and academic clinical studies (e.g. GLOMY, BEACON, GAMBIT, WTCC3 etc) 
Jump to: 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004
Number of items: 42.

2012

Freel, E.M., Mark, P.B., Weir, R.A.P., McQuarrie, E.P., Allan, K., Dargie, H.J., McClure, J.D., Jardine, A.G., Davies, E., and Connell, J.M.C. (2012) Demonstration of blood pressure-independent noninfarct myocardial fibrosis in primary aldosteronism: a cardiac magnetic resonance imaging study. Circulation: Cardiovascular Imaging, 5 (6). pp. 740-747. ISSN 1941-9651 (doi:10.1161/CIRCIMAGING.112.974576)

McQuarrie, E.P., Freel, E.M., Mark, P.B., Fraser, R., Patel, R.K., Dargie, H.G., Connell, J.M.C., and Jardine, A.G. (2012) Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease. Clinical Science, 123 (5). pp. 285-294. ISSN 0143-5221 (doi:10.1042/CS20120015)

Patel, R.K., Mark, P.B., Macnaught, G., Stevens, K.K., McQuarrie, E.P., Steedman, T., Gillis, K., Dargie, H.J., and Jardine, A.G. (2012) Altered relative concentrations of high-energy phosphates in patients with uraemic cardiomyopathy measured by magnetic resonance spectroscopy. Nephrology, Dialysis, Transplantation, 27 (6). pp. 2446-2451. ISSN 0931-0509 (doi:10.1093/ndt/gfr688)

2011

McQuarrie, E.P., Patel, R.K., Mark, P.B., Delles, C., Connell, J., Dargie, H.J., Steedman, T., and Jardine, A.G. (2011) Association between proteinuria and left ventricular mass index: a cardiac MRI study in patients with chronic kidney disease. Nephrology, Dialysis, Transplantation, 26 (3). pp. 933-938. ISSN 0931-0509 (doi:10.1093/ndt/gfq418)

Patel, R.K., Mark, P.B., Halliday, C., Steedman, T., Dargie, H. J., Cobbe, S.M., and Jardine, A.G. (2011) Microvolt T-Wave Alternans in End-Stage Renal Disease Patients--Associations with Uremic Cardiomyopathy. Clinical Journal of the American Society of Nephrology, 6 (3). pp. 519-527. ISSN 1555-9041 (doi:10.2215/CJN.06370710)

Stevens, K.K., McQuarrie, E.P., Sands, W., Hillyard, D.Z., Patel, R.K., Mark, P.B., and Jardine, A.G. (2011) Fibroblast growth factor 23 predicts left ventricular mass and induces cell adhesion molecule formation. International Journal of Nephrology, 2011 (297070). pp. 1-6. ISSN 2090-2158 (doi:10.4061/2011/297070)

2010

Collidge, T., Thomson, P., Mark, P., Willinek, W., and Roditi, G. (2010) Is this really a true case of NSF following Gadovist exposure alone? Nephrology, Dialysis, Transplantation, 25 (4). pp. 1352-1353. ISSN 0931-0509 (doi:10.1093/ndt/gfq014)

Mark, P. B., Patel, R. K., and Jardine, A. G. (2010) Screening for Coronary Artery Disease Before Renal Transplantation-Rational or Rationing? Transplantation, 89 (7). pp. 807-808. ISSN 0041-1337 (doi:10.1097/TP.0b013e3181cca6b6)

Patel, R.K., Jardine, A.G.M., Mark, P.B., Cunningham, A.F., Steedman, T., Powell, J.R., McQuarrie, E.P., Stevenson, K.K., Dargie, H.J., and Jardine, A.G. (2010) Association of left atrial volume with mortality among esrd patients with left ventricular hypertrophy referred for kidney transplant. American Journal of Kidney Diseases, 55 (6). pp. 1088-1096. ISSN 0272-6386 (doi:10.1053/j.ajkd.2009.12.033)

Thomson, P. C., Collidge, T. A., Mark, P.B., Traynor, J.P., Jardine, A.G., Morris, S. T. W., Simpson, K., and Roditi, G. H. (2010) Correction to the Relative Risk Calculation for Gadolinium-enhanced MR Imaging and Nephrogenic Systemic Fibrosis Response. Radiology, 255 (1). p. 308. ISSN 0033-8419

2009

Mark, P., Mccrea, I.V., Baxter, G.M., and McMillan, M. (2009) Hydronephrosis in a pregnant renal transplant patient. Transplantation Proceedings, 41 (9). pp. 3962-3963. ISSN 0041-1345 (doi:10.1016/j.transproceed.2009.05.031)

Patel, RK, Oliver, S, Mark, P, Powell, JR, McQuarrie, EP, Traynor, JP, Dargie, H, and Jardine, AG (2009) Determinants of Left Ventricular Mass and Hypertrophy in Hemodialysis Patients Assessed by Cardiac Magnetic Resonance Imaging. Clinical Journal of the American Society of Nephrology, 4 (9). pp. 1477-1483. ISSN 1555-9041 (doi:10.2215/CJN.03350509)

Weir, R. A.P., Chong, K. S., Dalzell, J. R., Petrie, C. J., Murphy, C. A., Steedman, T., Mark, P.B., McDonagh, T. A., Dargie, H. J., and McMurray, J. J.V. (2009) Plasma apelin concentration is depressed following acute myocardial infarction in man. European Journal of Heart Failure, 11 (6). pp. 551-558. ISSN 1388-9842 (doi:10.1093/eurjhf/hfp043)

Weir, R.A.P., Mark, P.B., Petrie, C.J., Clements, S., Steedman, T., Ford, I., Ng, L.L., Squire, I.B., Wagner, G.S., and McMurray, J.J.V. (2009) Left ventricular remodeling after acute myocardial infarction: Does eplerenone have an effect? American Heart Journal, 157 (6). pp. 1088-1096. ISSN 0002-8703 (doi:10.1016/j.ahj.2009.04.001)

2008

Patel, RK, Mark, P, Johnston, N, McGeoch, R, Lindsay, M, Dargie, H, and Jardine, AG (2008) Cardiovascular screening of potential renal transplant recipients provides no survival benefit. American Journal of Transplantation, 8 (s2). pp. 597-598. ISSN 1600-6135 (doi:10.1111/j.1600-6143.2008.02255.x)

Edward, M., Quinn, J.A., Mukherjee, S., Jensen, M.B., Jardine, A.G., Mark, P., and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214 (5). pp. 584-593. ISSN 0022-3417 (doi:10.1002/path.2311)

Doyle, A, Mark, PB, Johnston, N, Foster, J, Connell, J, Dargie, H, Jardine, A, and Padmanabhan, N (2008) Aortic stiffness and diastolic flow abnormalities in end-stage renal disease assessed by magnetic resonance imaging. Nephron Clinical Practice, 109 (1). C1-C8. ISSN 1660-2110 (doi:10.1159/000130170)

Mark, P, Doyle, A, Blyth, KG, Patel, RK, Weir, RAP, Steedman, T, Foster, JE, Dargie, H, and Jardine, AG (2008) Vascular function assessed with cardiovascular magnetic resonance predicts survival in patients with advanced chronic kidney disease. Journal of Cardiovascular Magnetic Resonance, 10 (39). ISSN 1097-6647 (doi:10.1186/1532-429X-10-39 )

Patel, RK, Mark, P, Johnston, N, McGregor, E, Dargie, H, and Jardine, AG (2008) Renal Transplantation Is Not Associated with Regression of Left Ventricular Hypertrophy: A Magnetic Resonance Study. Clinical Journal of the American Society of Nephrology, 3 (6). pp. 1807-1811. ISSN 1555-9041 (doi:10.2215/CJN.01400308)

Petrie, CJ, Mark, P, and Weir, RAP (2008) Broken pump or leaky filter? Renal dysfunction in heart failure a contemporary review. International Journal of Cardiology, 128 (2). pp. 154-165.

2007

Blyth, KG, Dargie, HJ, Foster, JE, Groenning, BA, Mark, PB, Martin, TN, Morton, JJ, Peacock, AJ, and Steedman, T (2007) NT-proBNP can be used to detect right ventricular systolic dysfunction in pulmonary hypertension. European Respiratory Journal, 29 . pp. 737-744. (doi:10.1183/09031936.00095606)

Collidge, TA, Jardine, AG, Mark, P, Morris, STW, Roditi, GH, Simpson, K, Thomson, PC, and Traynor, JP (2007) Gadolinium-enhanced MR imaging and nephrogenic systemic fibrosis: Retrospective study of a renal replacement therapy cohort. Radiology, 245 (1). pp. 168-175.

Collidge, TA, Mark, P, Thomson, PC, and Traynor, JP (2007) Imaging peripheral disease - Ga dolinium contrast may be risky in kidney disease. British Medical Journal, 334 (7608). pp. 1335-1336. ISSN 0959-535X

Hillyard, DZ, Nutt, CD, Thomson, J, McDonald, KJ, Wan, RK, Cameron, AJM, Mark, PB, and Jardine, AG (2007) Statins inhibit NK cell cytotoxicity by membrane raft depletion rather than inhibition of isoprenylation. Atherosclerosis, 191 . pp. 319-325. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2006.05.037)

Jardine, AG, Mark, P, and Patel, RK (2007) Are we overestimating left ventricular abnormalities in end-stage renal disease? Nephrology, Dialysis, Transplantation, 22 (7). pp. 1815-1819. ISSN 0931-0509

Jardine, AG, Mark, PB, and Petrie, CJ (2007) Diagnostic, prognostic, and therapeutic implications of brain natriuretic peptide in dialysis and nondialysis-dependent chronic renal failure. Seminars in Dialysis, 20 . pp. 40-49.

Wan, RK, Mark, PB, and Jardine, AG (2007) The cholesterol paradox is flawed; Cholesterol must be lowered in dialysis patients. Seminars in Dialysis, 20 . pp. 504-509. (doi:10.1111/j.1525-139X.2007.00359.x)

Zimmerli, LU, Mark, PB, Steedman, T, Foster, JE, Berg, GA, Dargie, HJ, Jardine, AG, Delles, C, and Dominiczak, AF (2007) Vascular function in patients with end-stage renal disease and/or coronary artery disease: A cardiac magnetic resonance imaging study. Kidney International, 71 . pp. 68-73. ISSN 0085-2538 (doi:10.1038/sj.ki.5002024)

2006

Blyth, KG, Dargie, HJ, Foster, JE, Groenning, BA, Jardine, AG, Johnston, N, Mark, PB, Martin, TN, and Steedman, T (2006) Redefinition of uremic cardiomyopathy by contrast-enhanced cardiac magnetic resonance imaging. Kidney International, 69 . pp. 1839-1845. ISSN 0085-2538 (doi:10.1038/sj.ki.5000249)

Jardine, AG, and Mark, P (2006) Cardiovascular magnetic resonance imaging has much to offer in the assessment of renal transplant recipients. American Journal of Transplantation, 6 (8). pp. 1975-1976. ISSN 1600-6135

Jardine, AG, Mark, P, and Wan, RK (2006) Cardiovascular disease management in renal transplant recipients: More or less treatment? Transplantation, 82 (6). pp. 737-738.

Mark, P, and Wan, RK (2006) Infected right atrial thrombus associated with a tunneled hemodialysis catheter. Kidney International, 69 (9). p. 1489. ISSN 0085-2538

Mark, PB, Stewart, GA, Gansevoort, RT, Petrie, CJ, McDonagh, TA, Dargie, H, Rodger, RSC, and Jardine, AG (2006) Diagnostic potential of circulating natriuretic peptides in chronic kidney disease. Nephrology, Dialysis, Transplantation, 21 . pp. 402-410. ISSN 0931-0509 (doi:10.1093/ndt/gfi187)

2005

Stewart, GA, Gansevoort, RT, Mark, PB, Rooney, E, McDonagh, TA, Dargie, H, Stuart, R, Rodger, C, and Jardine, AG (2005) Electrocardiographic abnormalities and uremic cardiomyopathy. Kidney International, 67 (1). pp. 217-226. ISSN 0085-2538 (doi:10.1111/j.1523-1755.2005.00072.x)

Blyth, KG, Dargie, HJ, Foster, JE, Groenning, BA, Mark, PB, Martin, TN, and Peacock, AJ (2005) Contrast enhanced-cardiovascular magnetic resonance imaging in patients with pulmonary hypertension. European Heart Journal, 26 . pp. 1993-1999. (doi:10.1093/eurheartj/ehi328)

Dargie, HJ, Mark, PB, and Petrie, CJ (2005) Cardiomyopathy in Becker muscular dystrophy - does regional fibrosis mimic infarction? Journal of Cardiovascular Magnetic Resonance, 7 . pp. 823-825. (doi:10.1080/10976640500295540)

Geddes, CC, Jardine, AG, Mark, PB, Rodger, RSC, Stewart, GA, Tan, CC, and Tutone, VK (2005) Hypertension, antihypertensive agents and outcomes following renal transplantation. Clinical Transplantation, 19 . pp. 181-192. (doi:10.1111/j.1399-0012.2004.00315.x)

Jardine, AG, Mark, PB, Mohammed, AS, Morris, STW, and Murphy, K (2005) Endothelial dysfunction in renal transplant recipients. Transplantation Proceedings, 37 . pp. 3805-3807. (doi:10.1016/j.transproceed.2005.09.116)

Mark, PB, Mazonakis, E, Rodger, RSC, Shapiro, D, and Spooner, RJ (2005) Pseudohypocalaemia in an elderly patient with advanced renal failure and renovascular disease. Nephrology, Dialysis, Transplantation, 20 . pp. 1499-1500. ISSN 0931-0509 (doi:10.1093/ndt/gfh836)

Mohamed, AS, Thomson, J, McDonald, KJ, Hillyard, DZ, Mark, PB, Elliott, HL, and Jardine, AG (2005) Circulating endothelial cells in renal transplant recipients. Transplantation Proceedings, 37 . pp. 2387-2390. (doi:10.1016/j.transproceed.2005.03.126)

2004

Buist, LJ, Deardon, D, Geddes, CC, Jardine, AG, Mark, PB, Revanur, V, Traynor, J, and Tutone, VK (2004) Random blood glucose measurements and survival in nondiabetic renal transplant recipients. Transplantation Proceedings, 36 . pp. 3006-3011. (doi:10.1016/j.transproceed.2004.10.067)

Cowan, M, Dargie, HJ, Foster, JE, Jardine, AG, Johnston, N, Mark, PB, Rodger, RSC, and Stewart, GA (2004) Determinants of hypertension and left ventricular function in end stage renal failure: a pilot study using cardiovascular magnetic resonance imaging. Clinical Physiology and Functional Imaging, 24 . pp. 387-393.

This list was generated on Thu May 2 11:01:11 2013 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Rapid diagnosis of acute kidney injury (AKT) following cardiac surgery using novel biomarkers - NGAL and urinary proteomics as biomarkers of acute kidney injury
    Tenovus-Scotland
    2012 - 2013