Institute of Cardiovascular and Medical Sciences

Dr Ole Kemi

  • Lecturer (Institute of Cardiovascular and Medical Sciences)

telephone: 01413305962
email: Ole.Kemi@glasgow.ac.uk


Cell biology and molecular physiology of the heart and muscle. We study the cardiac, skeletal, and vascular muscle under normal conditions, during pathological conditions such as myocardial infarction, heart failure, and cardiac myopathies, and after exercise training in both health and disease. This includes studying the cellular and molecular mechanistic events that underlie and translate into improved function and clinical outcome in health and disease, with the use of experimental exercise and disease models and biophysical, biochemical, molecular, physiology, and pharmacological methods.

Jump to: 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001
Number of items: 42.

2013

Kemi, O.J., Haram, P.M., Høydal, M.A., Wisløff, U., and Ellingsen, Ø. (2013) Exercise training and losartan improve endothelial function in heart failure rats by different mechanisms. Scandinavian Cardiovascular Journal . ISSN 1401-7431 (doi:10.3109/14017431.2012.754935)

2012

Kaurstad, G., Alves, M.N., Kemi, O.J., Rolim, N., Høydal, M.A., Wisløff, H., Stølen, T.O., and Wisløff, U. (2012) Chronic CaMKII inhibition blunts the cardiac contractile response to exercise training. European Journal of Applied Physiology, 112 (2). pp. 579-588. ISSN 1439-6319 (doi:10.1007/s00421-011-1994-0)

Kemi, O.J., MacQuaide, N., Hoydal, M.A., Ellingsen, O., Smith, G.L., and Wisloff, U. (2012) Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats. Journal of Cellular Physiology, 227 (1). pp. 20-26. ISSN 0021-9541 (doi:10.1002/jcp.22771)

2011

Koch, L.G. et al. (2011) Intrinsic aerobic capacity sets a divide for aging and longevity. Circulation Research, 109 (10). pp. 1162-1172. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.111.253807)

Helgerud, J., Rodas, G., Kemi, O.J., and Hoff, J. (2011) Strength and endurance in elite football players. International Journal of Sports Medicine, 32 (9). pp. 677-682. ISSN 0172-4622 (doi:10.1055/s-0031-1275742)

Kemi, O.J., Hoydal, M.A., MacQuaide, N., Haram, P.M., Koch, L.G., Britton, S.L., Ellingsen, O., Smith, G.L., and Wisloff, U. (2011) The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. Journal of Cellular Physiology, 226 (9). pp. 2235-2243. ISSN 0021-9541 (doi:10.1002/jcp.22559)

Kemi, O.J., Rognmo, O., Amundsen, B.H., Stordahl, S., Richardson, R.S., Helgerud, J., and Hoff, J. (2011) One-arm maximal strength training improves work economy and endurance capacity but not skeletal muscle blood flow. Journal of Sports Sciences, 29 (2). pp. 161-170. ISSN 0264-0414 (doi:10.1080/02640414.2010.529454)

2010

Kemi, O.J., and Wisløff, U. (2010) Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium. Acta Physiologica, 199 (4). pp. 425-439. ISSN 1748-1708 (doi:10.1111/j.1748-1716.2010.02132.x)

Menzies, P., Menzies, C., McIntyre, L., Paterson, P., Wilson, J., and Kemi, O.J. (2010) Blood lactate clearance during active recovery after an intense running bout depends on the intensity of the active recovery. Journal of Sports Sciences, 28 (9). pp. 975-982. ISSN 0264-0414 (doi:10.1080/02640414.2010.481721)

Smith, G., Reynolds, M., Burton, F.L., and Kemi, O.J. (2010) Confocal and multiphoton imaging of intracellular Ca2+. Methods in Cell Biology, 99 (10). pp. 255-261. ISSN 0091-679X (doi:10.1016/B978-0-12-374841-6.00009-8)

Wang, Y., Wisloff, U., and Kemi, O.J. (2010) Animal models in the study of exercise-induced cardiac hypertrophy. Physiological Research, 59 (5). pp. 633-644. ISSN 0862-8408

2009

Wisloff, U., Ellingsen, O., and Kemi, O.J. (2009) High-intensity interval training to maximize cardiac benefits of exercise training? Exercise and Sport Sciences Reviews, 37 (3). pp. 139-146. ISSN 0091-6331 (doi:10.1097/JES.0b013e3181aa65fc)

Kemi, O.J. (2009) Experimental evidence may inform the debate. Journal of Applied Physiology, 106 (1). p. 345. ISSN 8750-7587

Haram, P.M. et al. (2009) Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity. Cardiovascular Research, 81 (4). pp. 723-732. ISSN 0008-6363 (doi:10.1093/cvr/cvn332)

Stølen, T.O. et al. (2009) Interval training normalizes cCardiomyocyte function, diastolic Ca2+ control, and SR Ca2+ release synchronicity in a mouse model of diabetic cardiomyopathy. Circulation Research, 105 (6). pp. 527-536. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.109.199810)

2008

Bye, A., Hoydal, M.A., Catalucci, D., Langaas, M., Kemi, O.J., Beisvag, V., Koch, L.G., Britton, S.L., Ellingsen, O., and Wisloff, U. (2008) Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiological Genomics, 35 (3). pp. 213-221. ISSN 1094-8341 (doi:10.1152/physiolgenomics.90282.2008)

Kemi, O.J., Ellingsen, O., Smith, G.L., and Wisloff, U. (2008) Exercise-induced changes in calcium handling in left ventricular cardiomyocytes. Frontiers in Bioscience, 13 . pp. 356-368. ISSN 1093-9946 (doi:10.2741/2685)

Adamson, M., MacQuaide, N., Helgerud, J., Hoff, J., and Kemi, O.J. (2008) Unilateral arm strength training improves contralateral peak force and rate of force development. European Journal of Applied Physiology, 103 (5). pp. 553-559. ISSN 1439-6327 (doi:10.1007/s00421-008-0750-6)

Bye, A., Langaas, M., Høydal, M.A., Kemi, O.J., Heinrich, G., Koch, L.G., Britton, S.L., Najjar, S.M., Ellingsen, O., and Wisløff, U. (2008) Aerobic capacity-dependent differences in cardiac gene expression. Physiological Genomics, 33 . pp. 100-109. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00269.2007)

Kemi, O.J., Ceci, M., Condorelli, G., Smith, G.L., and Wisloff, U. (2008) Myocardial sarcoplasmic reticulurn Ca2+ ATPase function is increased by aerobic interval training. European Journal of Cardiovascular Prevention and Rehabilitation, 15 (2). pp. 145-148. ISSN 1741-8267 (doi:10.1097/HJR.0b013e3282efd4e0)

Kemi, O.J., Ceci, M., Wisloff, U., Grimaldi, S., Gallo, P., Smith, G.L., Condorelli, G., and Ellingsen, O. (2008) Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy. Journal of Cellular Physiology, 214 (2). pp. 316-321. ISSN 0021-9541 (doi:10.1002/jcp.21197)

Poole, D.C. et al. (2008) Exercise training does/does not induce vascular adaptations beyond the active muscle beds. Journal of Applied Physiology, 105 (3). pp. 1008-1010. ISSN 8750-7587 (doi:10.1152/japplphysiol.zdg-8158.pcpcomm.2008)

Schjerve, Inga E. et al. (2008) Both aerobic endurance and strength training programmes improve cardiovascular health in obese adults. Clinical Science, 115 (9). pp. 283-293. ISSN 0143-5221 (doi:10.1042/CS20070332)

Tjonna, A. E. et al. (2008) Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome: A Pilot Study. Circulation, 118 (4). pp. 346-354. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.108.772822)

2007

Kemi, O (2007) Temperature preconditioning: a cold-hearted answer to ischaemic-reperfusion injury ? Journal of Physiology, 585 (3). pp. 649-650. ISSN 0022-3751 (doi:10.1113/jphysiol.2007.146209)

Bye, A., Langaas, M., Hoydal, M.A., Kemi, O.J., Heinrich, G., Koch, L.G., Britton, S.L., Najjar, S.M., Ellingsen, O., and Wisloff, U. (2007) Aerobic capacity-dependent differences in cardiac gene expression. Physiological Genomics, 33 (1). pp. 100-109. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00269.2007)

Hoydal, MA, Wisloff, U, Kemi, OJ, Britton, SL, Koch, LG, Smith, GL, and Ellingsen, O (2007) Nitric oxide synthase type-1 modulates cardiomyocyte contractility and calcium handling: association with low intrinsic aerobic capacity. European Journal of Cardiovascular Prevention and Rehabilitation, 14 (2). pp. 319-325. ISSN 1741-8267

Kemi, O (2007) Adaptation of endothelium to exercise training: Insights from experimental studies. Frontiers in Bioscience, 13 (ISS 1). pp. 336-346. (doi:10.2741/2683)

Kemi, O (2007) Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training. European Journal of Cardiovascular Prevention and Rehabilitation, 14 (6). pp. 753-760. ISSN 1741-8267

Kemi, OJ, Ellingsen, O, Ceci, M, Grimaldi, S, Smith, GL, Condorelli, G, and Wisloff, U (2007) Aerobic interval training enhances cardiomyocyte contractility and Ca2+ cycling by phosphorylation of CaMKII and Thr-17 of phospholamban. Journal of Molecular and Cellular Cardiology, 43 (3). pp. 354-361. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2007.06.013)

Kemi, OJ, Hoydal, MA, Haram, PM, Garnier, A, Fortin, D, Ventura-Clapier, R, and Ellingsen, O (2007) Exercise training restores aerobic capacity and energy transfer systems in heart failure treated with losartan. Cardiovascular Research, 76 . pp. 91-99. (doi:10.1016/j.cardiores.2007.06.008)

2006

Kemi, O (2006) Time-course of endothelial adaptation following acute and regular exercise. European Journal of Cardiovascular Prevention and Rehabilitation, 13 (4). pp. 585-591. (doi:10.1097/01.hjr.0000198920.57685.)

Kemi, OJ, Arbo, I, Hoydal, MA, Loennechen, JP, Wisloff, U, Smith, GL, and Ellingsen, O (2006) Reduced pH and contractility in failing rat cardiomyocytes. Acta Physiologica, 188 (3-4). pp. 185-193. ISSN 1748-1708 (doi:10.1111/j.1748-1716.2006.01621.x)

2005

Kemi, O (2005) Effective training for patients with intermittent claudication. Scandinavian Cardiovascular Journal, 39 (4). pp. 244-249. (doi:10.1080/14017430510035844)

Kemi, O (2005) Moderate vs. high exercise intensity: Differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function. Cardiovascular Research, 67 (1). pp. 161-172. (doi:10.1016/j.cardiores.2005.03.010)

Kemi, O (2005) Strength and endurance differences between elite and junior elite ice hockey players. The importance of allometric scaling. International Journal of Sports Medicine, 26 (7). pp. 537-541. (doi:10.1055/s-2004-821328)

Kemi, O (2005) Trans-sodium crocetinate does not affect oxygen uptake in rats during treadmill running. Scandinavian Journal of Clinical and Laboratory Investigation, 65 (7). pp. 577-584. (doi:10.1080/00291950500228121)

2004

Kemi, O (2004) Aerobic fitness is associated with cardiomyocyte contractile capacity and endothelial function in exercise training and detraining. Circulation, 109 (23). pp. 2897-2904. (doi:10.1161/01.CIR.0000129308.04757.)

2003

Kemi, O (2003) Soccer specific testing of maximal oxygen uptake. Journal of Sports Medicine and Physical Fitness, 43 (2). pp. 139-144.

2002

Kemi, O (2002) Intensity-controlled treadmill running in mice: cardiac and skeletal muscle hypertrophy. Journal of Applied Physiology, 93 (4). pp. 1301-1309. (doi:10.1152/japplphysiol.00231.2002)

Kemi, O (2002) Soccer specific aerobic endurance training. British Journal of Sports Medicine, 36 (3). pp. 218-221. (doi:10.1136/bjsm.36.3.218)

2001

Kemi, O. (2001) Intensity-controlled treadmill running in rats: VO2max and cardiac hypertrophy. American Journal of Physiology: Heart and Circulatory Physiology, 280 (3). H1301-H1310. ISSN 0363-6135

This list was generated on Thu May 2 10:11:09 2013 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Cardiac CaMK in heart failure and exercise training
    British Heart Foundation
    2010 - 2013
     
  • Cellular basis for alternating T-wave morphology in isolated rabbit hearts
    British Heart Foundation
    2009 - 2012
     

Grant Advisory Board

  • 2006 - ongoing: European Association for Cardiovascular Prevention and Rehabilitation - Nucleus member of the Basic Science Committee

Invited International Presentations

  • 2011: Trondheim, Norway - KG Jebsen Center of Excellence
  • 2011: Paris, France - European Society of Cardiology
  • 2010: Stockholm, Sweden - ESC 2010, European Society of Cardiology Symposium Chair
  • 2010: Manchester, UK - 'Physiology 2010' - The Physiological Society
  • 2010: Trondheim, Norway - Norwegian University of Science and Technology
  • 2010: Prague, Czech Republic - Europrevent 2010, European Society of Cardiology Symposium Chair
  • 2010: Glasgow, UK - British Association of Sport and Exercise Sciences
  • 2009: Leeds, UK - University of Leeds
  • 2009: Barcelona, Spain - ESC 2009, European Society of Cardiology
  • 2008: Paris, France - EuroPrevent 2008, The European Society of Cardiology
  • 2008: Cambridge, UK - Physiology 2008, The Physiological Society
  • 2008: Cambridge, UK - Physiology 2008, The Physiological Society Symposium Chair and Organiser
  • 2008: Trondheim, Norway - Exercise in Medicine, The Norwegian University of Science and Technology Symposium Chair
  • 2008: Trondheim, Norway - Exercise in Medicine, The Norwegian University of Science and Technology
  • 2008: Munich, Germany - ESC 2008, European Society of Cardiology
  • 2008: Manchester, UK - The Physiological Society
  • 2007: Glasgow, Scotland - University of Strathclyde
  • 2007: Glasgow, Scotland - Life Sciences
  • 2007: Baltimore, MD, USA - The Biophysical Society Platform Session Chair
  • 2007: Madrid, Spain - EuroPrevent 2007, European Society of Cardiology
  • 2007: Vienna, Austria - European Society of Cardiology Symposium Chair
  • 2006: Leeds, UK - Northern Cardiovascular Research Group Meeting
  • 2006: San Diego, USA - University of California
  • 2006: Trondheim, Norway - Exercise in Medicine, The Norwegian University of Science and Technology.
  • 2005: Boston, USA - Beth Israel Deaconess Medical Center, Harvard Medical School
  • 2004: Trondheim, Norway - Cellular Biology of Exercise Training, The Norwegian University of Science and Technology
  • 2003: Oslo, Norway - Nordic Pediatric Cardiology Meeting

Prizes, Awards and Distinctions

  • 2010: Fellow of the European Society of Cardiology
  • 2009: New Investigator Award of the American College of Sports Medicine
  • 2008: Fellow of The Higher Education Academy, UK.
  • 2006: International Research Award, Biophysical Society, Baltimore, USA.
  • 2002: International Student Award, American College of Sports Medicine, St. Louis, USA.
  • 2002: Short-listed Nycomed Pharma Award, Norwegian Medical Association, Trondheim, Norway.

Professional Learned Society

  • 2006 - ongoing: Physiological Society - Member
  • 2006 - ongoing: Biophysical Society
  • 2005 - ongoing: Federation of European Biochemical Societies (FEBS)
  • 2003 - ongoing: American Association for the Advancement of Science
  • 2002 - ongoing: European Society of Cardiology - Fellow
  • 2002 - ongoing: American Physiological Society
  • 2000 - ongoing: Norwegian Society of Cardiology
  • 1999 - ongoing: American College of Sports Medicine

Research Fellowship

  • 2001 - 2005: Norwegian University of Science and Technology, Trondheim, Norway, University Research Fellowship
  • 2001 - 2003: John Hopkins University, Instructor