Dr Marie-Ann Ewart

  • University Teacher (Centre for Neuroscience)

telephone: 01413307400
email: Marie-Ann.Ewart@glasgow.ac.uk

Research interests

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • The role of AMP-activated protein kinase in adipocyte glucose transport and insulin signalling - utilising a knockout mouse model
    Diabetes UK
    2012 - 2013
     
  • The sensitive assessment of the activity of cellular signalling pathways regulating insulin action and the cardiovascular complications of diabetes
    Diabetes UK
    2011 - 2014
     
  • Involvement of AMPK in calcium regulation in atherosclerotic blood vessels.
    British Heart Foundation
    2011 - 2014
     

Publications

List by: Type | Date

Jump to: 2014 | 2012 | 2011 | 2008 | 2007 | 2006 | 2005 | 2004 | 2002
Number of items: 18.

2014

Farmer, D. G.S., Ewart, M.-A., Mair, K. M., and Kennedy, S. (2014) Soluble receptor for advanced glycation end products (sRAGE) attenuates haemodynamic changes to chronic hypoxia in the mouse. Pulmonary Pharmacology and Therapeutics, 29 (1). pp. 7-14. ISSN 1094-5539 (doi:10.1016/j.pupt.2014.01.002)

Ewart, M.-A., Kennedy, S., MacMillan, D., Raja, A. L.N., Watt, I. M., and Currie, S. (2014) Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis. Atherosclerosis, 234 (1). pp. 154-161. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2014.02.014)

Almabrouk, T.A.M., Ewart, M.-A., Salt, I.P., and Kennedy, S. (2014) Perivascular fat, AMP-activated protein kinase and vascular diseases. British Journal of Pharmacology, 171 (3). pp. 595-617. ISSN 0007-1188 (doi:10.1111/bph.12479)

2012

Ewart, M.-A., and Kennedy, S. (2012) Diabetic cardiovascular disease AMP-activated protein kinase (AMPK) as a therapeutic target. Cardiovascular and Hematological Agents in Medicinal Chemistry, 10 (3). pp. 190-211. ISSN 1871-5257 (doi:10.2174/187152512802651015 )

Watt, J., Ewart, M.-A., Greig, F. H., Oldroyd, K. G., Wadsworth, R. M., and Kennedy, S. (2012) The effect of reactive oxygen species on whole blood aggregation and the endothelial cell-platelet interaction in patients with coronary heart disease. Thrombosis Research, 130 (2). pp. 210-215. ISSN 0049-3848 (doi:10.1016/j.thromres.2012.03.024)

Watt, J., Ewart, M.-A., Greig, F.H., Oldroyd, K.G., Wadsworth, R.M., and Kennedy, S. (2012) The effect of reactive oxygen species on whole blood aggregation and the enothelial cell-platelet interaction in patients with coronary heart disease. Thrombosis Research, 130 (2). pp. 210-215. ISSN 0049-3848 (doi:10.1016/j.thromres.2012.03.024)

2011

Ewart, M.-A., and Kennedy, S. (2011) AMPK and vasculoprotection. Pharmacology and Therapeutics, 131 (2). pp. 242-253. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2010.11.002)

Reihill, J., Ewart, M.-A., and Salt, I.P. (2011) The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells. Vascular Cell, 3 (1). p. 9. ISSN 2045-824X (doi:10.1186/2045-824X-3-9)

2008

Currie, S., Rainbow, R.D., Ewart, M.-A., Kitson, S., Pliego, E.H., Kane, K.A., and McCarron, J.G. (2008) IP(3)R-mediated Ca(2+) release is modulated by anandamide in isolated cardiac nuclei. Journal of Molecular and Cellular Cardiology, 45 (6). pp. 804-811. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2008.07.005)

Ewart, M.-A., Kohlhaas, C.F., and Salt, I.P. (2008) Inhibition of tumor necrosis factor α–stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase. Arteriosclerosis, Thrombosis and Vascular Biology, 28 (12). pp. 2255-2257. ISSN 1079-5642 (doi:10.1161/ATVBAHA.108.175919)

Boyle, J. G., Logan, P. J., Ewart, M.-A., Reihill, J. A., Ritchie, S. A., Connell, J. M.C., Cleland, S. J., and Salt, I. P. (2008) Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase. Journal of Biological Chemistry, 283 (17). pp. 11210-11217. ISSN 0021-9258 (doi:10.1074/jbc.M710048200)

2007

Reihill, J.A., Ewart, M.-A., Hardie, D.G., and Salt, I. (2007) AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production. Biochemical and Biophysical Research Communications, 354 (4). pp. 1084-1088. ISSN 0006-291X (doi:10.1016/j.bbrc.2007.01.110)

2006

Anitei, M., Ifrim, M., Ewart, M.-A., Cowan, A.E., Carson, J.H., Bansal, R., and Pfeiffer, S.E. (2006) A role for Sec8 in oligodendrocyte morphological differentiation. Journal of Cell Science, 119 (5). pp. 807-818. ISSN 0021-9533 (doi:10.1242/​jcs.02785)

Clarke, M., Ewart, M.A., Santy, L.C., Prekeris, R., and Gould, G.W. (2006) ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway. Biochemical and Biophysical Research Communications, 342 . pp. 1361-1367. ISSN 0006-291X (doi:10.1016/j.bbrc.2006.02.102)

2005

Ewart, M.-A., Clarke, M., Kane, S., Chamberlain, L.H., and Gould, G.W. (2005) Evidence for a role of the exocyst in insulin-stimulated Glut4 trafficking in 3T3-L1 adipocytes. Journal of Biological Chemistry, 280 . pp. 3812-3816. ISSN 0021-9258 (doi:10.1074/jbc.M409928200)

Tsuboi, T., Ravier, M.A., Xie, H., Ewart, M.-A., Gould, G.W., Baldwin, S.A., and Rutter, G.A. (2005) Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis. Journal of Biological Chemistry, 280 (27). pp. 25565-25570. ISSN 0021-9258 (doi:10.1074/jbc.M501674200)

2004

Ritchie, S., Ewart, M., Perry, C., Connell, J., and Salt, I. (2004) The role of insulin and the adipocytokines in regulation of vascular endothelial function. Clinical Science, 107 (6). pp. 519-532. ISSN 0143-5221 (doi:10.1042/CS20040190)

2002

Ewart, M., Ozanne, B., and Cushley, W. (2002) The CD23a and CD23b proximal promoters display different sensitivities to exogenous stimuli in B lymphocytes. Genes and Immunity, 3 (3). pp. 158-164. ISSN 1466-4879 (doi:10.1038/sj/gene/6363848)

This list was generated on Fri Oct 24 10:29:44 2014 BST.
Jump to: Article
Number of items: 18.

Article

Farmer, D. G.S., Ewart, M.-A., Mair, K. M., and Kennedy, S. (2014) Soluble receptor for advanced glycation end products (sRAGE) attenuates haemodynamic changes to chronic hypoxia in the mouse. Pulmonary Pharmacology and Therapeutics, 29 (1). pp. 7-14. ISSN 1094-5539 (doi:10.1016/j.pupt.2014.01.002)

Ewart, M.-A., Kennedy, S., MacMillan, D., Raja, A. L.N., Watt, I. M., and Currie, S. (2014) Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis. Atherosclerosis, 234 (1). pp. 154-161. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2014.02.014)

Almabrouk, T.A.M., Ewart, M.-A., Salt, I.P., and Kennedy, S. (2014) Perivascular fat, AMP-activated protein kinase and vascular diseases. British Journal of Pharmacology, 171 (3). pp. 595-617. ISSN 0007-1188 (doi:10.1111/bph.12479)

Ewart, M.-A., and Kennedy, S. (2012) Diabetic cardiovascular disease AMP-activated protein kinase (AMPK) as a therapeutic target. Cardiovascular and Hematological Agents in Medicinal Chemistry, 10 (3). pp. 190-211. ISSN 1871-5257 (doi:10.2174/187152512802651015 )

Watt, J., Ewart, M.-A., Greig, F. H., Oldroyd, K. G., Wadsworth, R. M., and Kennedy, S. (2012) The effect of reactive oxygen species on whole blood aggregation and the endothelial cell-platelet interaction in patients with coronary heart disease. Thrombosis Research, 130 (2). pp. 210-215. ISSN 0049-3848 (doi:10.1016/j.thromres.2012.03.024)

Watt, J., Ewart, M.-A., Greig, F.H., Oldroyd, K.G., Wadsworth, R.M., and Kennedy, S. (2012) The effect of reactive oxygen species on whole blood aggregation and the enothelial cell-platelet interaction in patients with coronary heart disease. Thrombosis Research, 130 (2). pp. 210-215. ISSN 0049-3848 (doi:10.1016/j.thromres.2012.03.024)

Ewart, M.-A., and Kennedy, S. (2011) AMPK and vasculoprotection. Pharmacology and Therapeutics, 131 (2). pp. 242-253. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2010.11.002)

Reihill, J., Ewart, M.-A., and Salt, I.P. (2011) The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells. Vascular Cell, 3 (1). p. 9. ISSN 2045-824X (doi:10.1186/2045-824X-3-9)

Currie, S., Rainbow, R.D., Ewart, M.-A., Kitson, S., Pliego, E.H., Kane, K.A., and McCarron, J.G. (2008) IP(3)R-mediated Ca(2+) release is modulated by anandamide in isolated cardiac nuclei. Journal of Molecular and Cellular Cardiology, 45 (6). pp. 804-811. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2008.07.005)

Ewart, M.-A., Kohlhaas, C.F., and Salt, I.P. (2008) Inhibition of tumor necrosis factor α–stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase. Arteriosclerosis, Thrombosis and Vascular Biology, 28 (12). pp. 2255-2257. ISSN 1079-5642 (doi:10.1161/ATVBAHA.108.175919)

Boyle, J. G., Logan, P. J., Ewart, M.-A., Reihill, J. A., Ritchie, S. A., Connell, J. M.C., Cleland, S. J., and Salt, I. P. (2008) Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase. Journal of Biological Chemistry, 283 (17). pp. 11210-11217. ISSN 0021-9258 (doi:10.1074/jbc.M710048200)

Reihill, J.A., Ewart, M.-A., Hardie, D.G., and Salt, I. (2007) AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production. Biochemical and Biophysical Research Communications, 354 (4). pp. 1084-1088. ISSN 0006-291X (doi:10.1016/j.bbrc.2007.01.110)

Anitei, M., Ifrim, M., Ewart, M.-A., Cowan, A.E., Carson, J.H., Bansal, R., and Pfeiffer, S.E. (2006) A role for Sec8 in oligodendrocyte morphological differentiation. Journal of Cell Science, 119 (5). pp. 807-818. ISSN 0021-9533 (doi:10.1242/​jcs.02785)

Clarke, M., Ewart, M.A., Santy, L.C., Prekeris, R., and Gould, G.W. (2006) ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway. Biochemical and Biophysical Research Communications, 342 . pp. 1361-1367. ISSN 0006-291X (doi:10.1016/j.bbrc.2006.02.102)

Ewart, M.-A., Clarke, M., Kane, S., Chamberlain, L.H., and Gould, G.W. (2005) Evidence for a role of the exocyst in insulin-stimulated Glut4 trafficking in 3T3-L1 adipocytes. Journal of Biological Chemistry, 280 . pp. 3812-3816. ISSN 0021-9258 (doi:10.1074/jbc.M409928200)

Tsuboi, T., Ravier, M.A., Xie, H., Ewart, M.-A., Gould, G.W., Baldwin, S.A., and Rutter, G.A. (2005) Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis. Journal of Biological Chemistry, 280 (27). pp. 25565-25570. ISSN 0021-9258 (doi:10.1074/jbc.M501674200)

Ritchie, S., Ewart, M., Perry, C., Connell, J., and Salt, I. (2004) The role of insulin and the adipocytokines in regulation of vascular endothelial function. Clinical Science, 107 (6). pp. 519-532. ISSN 0143-5221 (doi:10.1042/CS20040190)

Ewart, M., Ozanne, B., and Cushley, W. (2002) The CD23a and CD23b proximal promoters display different sensitivities to exogenous stimuli in B lymphocytes. Genes and Immunity, 3 (3). pp. 158-164. ISSN 1466-4879 (doi:10.1038/sj/gene/6363848)

This list was generated on Fri Oct 24 10:29:44 2014 BST.