2013

Brown, K.M. et al. (2013) Phosphodiesterase-8A binds to and regulates Raf-1 kinase. Proceedings of the National Academy of Sciences of the United States of America . ISSN 0027-8424 (doi:10.1073/pnas.1303004110) (In Press)

2011

Le Moan, N., Houslay, D.M., Christian, F., Houslay, M.D., and Akassoglou, K. (2011) Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α. Molecular Cell, 44 (3). pp. 476-490. ISSN 1097-2765 (doi:10.1016/j.molcel.2011.08.033)

Christian, F. et al. (2011) Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. Journal of Biological Chemistry, 286 (11). pp. 9079-9096. ISSN 0021-9258 (doi:10.1074/jbc.M110.160614)

Day, J.P. et al. (2011) Elucidation of a Structural Basis for the Inhibitor-Driven, p62 (SQSTM1)-Dependent Intracellular Redistribution of cAMP Phosphodiesterase-4A4 (PDE4A4). Journal of Medicinal Chemistry, 54 (9). pp. 3331-3347. ISSN 0022-2623 (doi:10.1021/jm200070e)

Edwards, H.V., Christian, F., and Baillie, G.S. (2011) cAMP: Novel concepts in compartmentalised signalling. Seminars in Cell and Developmental Biology . ISSN 1084-9521 (doi:10.1016/j.semcdb.2011.09.005)

Sin, Y.Y., Edwards, H.V., Li, X., Day, J.P., Christian, F., Dunlop, A.J., Adams, D.R., Zaccolo, M., Houslay, M.D., and Baillie, G.S. (2011) Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes. Journal of Molecular and Cellular Cardiology, 50 (5). pp. 872-883. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2011.02.006)

2010

Christian, F., Anthony, D.F., Vadrevu, S., Riddell, T., Day, J.P., McLeod, R., Adams, D.R., Baillie, G.S., and Houslay, M.D. (2010) p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways. Cellular Signalling, 22 (10). pp. 1576-1596. ISSN 0898-6568 (doi:10.1016/j.cellsig.2010.06.003)

Houslay, M.D., and Christian, F. (2010) p62 (SQSTM1) forms part of a novel, reversible aggregate containing a specific conformer of the cAMP degrading phosphodiesterase, PDE4A4. Autophagy, 6 (8). pp. 1198-1200. ISSN 1554-8627 (doi:10.4161/auto.6.8.13479)