Dr Francis Burton
- Research Technologist (Institute of Cardiovascular and Medical Sciences)
telephone: 01413306598
email: Francis.Burton@glasgow.ac.uk
Role of Contraction-Excitation Feedback in Ventricular Arrythmogenesis*
Article
Kelly, A., Ghouri, I.A., Kemi, O.J., Bishop, M., Bernus, O., Fenton, F.H., Myles, R.C., Burton, F.L., and Smith, G.L. (2013) Sub-epicardial action potential characteristics are a function of depth and activation sequence in isolated rabbit hearts. Circulation: Arrhythmia and Electrophysiology, 6 (4). pp. 809-817. ISSN 1941-3149 (doi:10.1161/CIRCEP.113.000334)
Kettlewell, S., Burton, F.L., Smith, G.L., and Workman, A.J. (2013) Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarisations and fibrillation. Cardiovascular Research, 99 (1). pp. 215-224. ISSN 0008-6363 (doi:10.1093/cvr/cvt087)
Di Diego, J.M., Sicouri, S., Myles, R.C., Burton, FL., Smith, G.L., and Antzelevitch, C. (2013) Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations. Journal of Molecular and Cellular Cardiology, 54 . pp. 53-64. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2012.10.017)
Kelly, A., Ghouri, I.A., Kemi, O.J., Bishop, M.J., Bernus, O., Fenton, F.H., Myles, R.C., Burton, F.L., and Smith, G.L. (2013) Subepicardial action potential characteristics are a function of depth and activation sequence in isolated rabbit hearts. Circulation: Arrhythmia and Electrophysiology, 6 (4). pp. 809-817. ISSN 1941-3149 (doi:10.1161/CIRCEP.113.000334)
Kettlewell, S., Burton, F.L., Smith, G.L., and Workman, A.J. (2013) Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarizations, and fibrillation. Cardiovascular Research, 99 (1). pp. 215-224. ISSN 0008-6363 (doi:10.1093/cvr/cvt087)
Cheng, H., Smith, G.L., Orchard, C.H., Hancox, J.C., and Burton, F.L. (2012) Inhibition of sarcoplasmic reticulum Ca2+-ATPase decreases atrioventricular node-paced heart rate in rabbits. Experimental Physiology, 97 (10). pp. 1131-1139. ISSN 0958-0670 (doi:10.1113/expphysiol.2012.065110)
Myles, R., Burton, F.L., Cobbe, S., and Smith, G.L. (2011) Alternans of action potential duration and amplitude in rabbits with left ventricular dysfunction following myocardial infarction. Journal of Molecular and Cellular Cardiology, 50 (3). pp. 510-512. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2010.11.019 )
Burton, F.L., Malkova, D., Caslake, M.J., and Gill, J.M.R. (2010) Substrate metabolism, appetite and feeding behaviour under low and high energy turnover conditions in overweight women. British Journal of Nutrition, 104 (8). pp. 1249-1259. ISSN 0007-1145 (doi:10.1017/S0007114510002023)
Myles, R.C., Bernus, O., Burton, F.L., Cobbe, S.M., and Smith, G.L. (2010) The effect of activation sequence on transmural patterns of repolarization and action potential duration in rabbit ventricular myocardium. American Journal of Physiology: Heart and Circulatory Physiology, 289 (8). H1812-H1822. ISSN 0363-6135 (doi:10.1152/ajpheart.00518.2010)
Smith, G., Reynolds, M., Burton, F.L., and Kemi, O.J. (2010) Confocal and multiphoton imaging of intracellular Ca2+. Methods in Cell Biology, 99 (10). pp. 255-261. ISSN 0091-679X (doi:10.1016/B978-0-12-374841-6.00009-8)
Burton, F.L., Malkova, D., Caslake, M.J., and Gill, J.M.R. (2008) Energy replacement attenuates the effects of prior moderate exercise on postprandial metabolism in overweight/obese men. International Journal of Obesity, 32 (3). pp. 481-489. ISSN 0307-0565 (doi:10.1038/sj.ijo.0803754)
Lang, N.N., Myles, R.C., Burton, F.L., Hall, D.P., Chin, Y.Z., Boon, N.A., and Newby, D.E. (2008) The vascular effects of rotigaptide in vivo in man. Biochemical Pharmacology, 76 (10). pp. 1194-1200. ISSN 0006-2952 (doi:10.1016/j.bcp.2008.08.022 )
Myles, R.C., Burton, F.L., Cobbe, S.M., and Smith, G.L. (2008) The link between repolarisation alternans and ventricular arrhythmia: Does the cellular phenomenon extend to the clinical problem? Journal of Molecular and Cellular Cardiology, 45 (1). pp. 1-10. ISSN 0022-2828 (doi:10.1016/j.yjmcc.2008.03.024)
Caldwell, J, Burton, FL, Smith, GL, and Cobbe, SM (2007) Heterogeneity of ventricular fibrillation dominant frequency during global ischemia in isolated rabbit hearts. Journal of Cardiovascular Electrophysiology, 18 (8). pp. 854-861. ISSN 1540-8167 (doi:10.1111/j.1540-8167.2007.00867.x)
Walker, NL, Burton, FL, Kettlewell, S, Smith, GL, and Cobbe, SM (2007) Mapping of epicardial activation in a rabbit model of chronic myocardial infarction: Response to atrial, endocardial, and epicardial pacing. Journal of Cardiovascular Electrophysiology, 18 (8). pp. 862-868. ISSN 1540-8167 (doi:10.1111/j.1540-8167.2007.00858.x)
Kohl, P, Camelliti, P, Burton, FL, and Smith, GL (2005) Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation. Journal of Electrocardiology, 38 (4). pp. 45-50. ISSN 0022-0736 (doi:10.1016/j.jelectrocard.2005.06.096)
Kettlewell, S, Walker, NL, Cobbe, SM, Burton, FL, and Smith, GL (2004) The electrophysiological and mechanical effects of 2,3-butane-dione monoxime and cytochalasin-D in the Langendorff perfused rabbit heart. Experimental Physiology, 89 (2). pp. 163-172. ISSN 0958-0670 (doi:10.1113/expphysiol.2003.026732)
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Cellular basis for alternating T-wave morphology in isolated rabbit hearts
British Heart Foundation
2009 - 2012
- Atrial remodelling of calcium handling and electrophysiology in heart failure.
British Heart Foundation
2009 - 2013
- Atrioventricular nodal function in a rabbit model of chronic heart failure
British Heart Foundation
2005 - 2007
- Factors affecting the success of defibrillation in ischaemia
British Heart Foundation
2004 - 2007
