Institute of Cardiovascular and Medical Sciences

Dr Dilys Freeman

Dr Dilys Freeman
  • Senior Lecturer (Institute of Cardiovascular and Medical Sciences)

telephone: 01412112785
email: Dilys.Freeman@glasgow.ac.uk


After studying Biochemistry at the University of Edinburgh Dr Dilys Freeman undertook her PhD in industry at Glaxo Group Research in Middlesex. Postdoctoral positions in Glasgow and the University of Texas Southwestern Medical Center at Dallas were followed by her first academic appointment in Biological Science at the University of Durham. Dr Dilys Freeman joined the University of Glasgow in 1999.

Dr Freeman's early research was in the field of cardiovascular disease in particular lipid and lipoprotein metabolism. She studied cholesteryl ester transfer protein and its role in high density lipoprotein metabolism as well as the genetic regulation of plasma high density lipoprotein and low density lipoprotein levels. Dilys has been involved in the analysis of the West of Scotland Coronary Prevention Study (WOSCOPS), in particular the influence of inflammation, statins and genetics on the aetiology of type 2 diabetes.

Recent research is in the field of metabolism in pregnancy and its vascular complications such as preeclampsia and growth restriction. Again the focus is on lipid and carbohydrate metabolism, inflammation and the influence of genetic markers in obese pregnancy and on the development of adverse pregnancy outcome. The link between pregnancy complications and future maternal cardiovascular disease is an important part of this research. The metabolic cross-talk between mother and baby and its regulation by the placenta is a new area of interest with long term disease implications for the offspring.

Research:

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List all by: Type | Date

Jump to: 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001
Number of items: 52.

2013

Meyer, B.J., Stewart, F.M., Brown, E.A., Cooney, J., Nilsson, S., Olivecrona, G., Ramsay, J.E., Griffin, B.A., Caslake, M.J., and Freeman, D.J. (2013) Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester. Journal of Clinical Endocrinology and Metabolism, 98 (2). pp. 643-652. ISSN 0021-972X (doi:10.1210/jc.2012-3481)

Hodson, L., Neville, M., Chong, M.F.-F., Rogers, I., Huda, S.S., Freeman, D.J., Frayn, K.N., and Fielding, B.A. (2013) Micro-techniques for analysis of human adipose tissue fatty acid composition in dietary studies. Nutrition, Metabolism and Cardiovascular Diseases . ISSN 0939-4753 (doi:10.1016/j.numecd.2012.11.003) (In Press)

2012

Mackenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D., Freeman, D.J., Dominiczak, A.F., McBride, M.W., and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119 (13). pp. 1564-1571. ISSN 1470-0328 (doi:10.1111/1471-0528.12016)

Carty, D.M., Anderson, L.A., Freeman, D.J., Welsh, P.I., Brennand, J.E., Dominiczak, A.F., and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30 (5). pp. 954-959. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328352573b)

Bernini, F. et al. (2012) European lipoprotein club: report of the 34th ELC annual conference, Tutzing, 5–8 September 2011. Atherosclerosis, 221 (1). pp. 287-293. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2011.12.002)

Mackay, V.A. et al. (2012) Preeclampsia is associated with compromized maternal synthesis of long chain polyunsaturated fatty acids leading to offspring deficiency. Hypertension, 60 (4). pp. 1078-1085. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.112.197897)

Sattar, N., and Freeman, D.J. (2012) Potential mechanisms contributing to gestational diabetes and pre-eclampsia in the obese woman. In: Gillman, M.W. and Poston, L. (eds.) Maternal Obesity. Series: Cambridge medicine . Cambridge University Press, Cambridge, UK, pp. 45-55. ISBN 978107003965

Sattar, N., and Freeman, D.J. (2012) Potential mechanisms contributing to gestational diabetes and preeclampsia in the obese woman. In: Gillman, M.W. and Poston, L. (eds.) Maternal Obesity. Cambridge University Press . ISBN 9781107003965

2011

Bernini, F., Fisher, R., Freeman, D.J., Groen, A., Kalopissis, A., Malle, E., Mulder, M., Niemeier, A., Parini, P., and Hansen, A.T. (2011) Report of the 33rd Annual Conference of the European Lipoprotein Club, Tutzing, 6–9 September 2010. Atherosclerosis, 215 (1). pp. 249-255. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2010.12.002)

Freeman, D. et al. (2011) Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). BMC Geriatrics, 11 (8). ISSN 1471-2318 (doi:10.1186/1471-2318-11-8)

2010

Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375 (9716). pp. 735-742. ISSN 0140-6736 (doi:10.1016/S0140-6736(09)61965-6)

Fisher, R. et al. (2010) European Lipoprotein Club: Report of the 32nd ELC Annual Conference, Tutzing, 7–10 September 2009. Atherosclerosis, 210 (2). pp. 680-686. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2009.12.038)

Freeman, D.J. (2010) Effects of maternal obesity on fetal growth and body composition: implications for programming and future health. Seminars in Fetal and Neonatal Medicine, 15 (2). pp. 113-118. ISSN 1744-165X (doi:10.1016/j.siny.2009.09.001 Univ Glasgow, Western Infirm, Fac Med, Glasgow G11 6NT, Lanark, Scotland.)

Freeman, D.J., and Sattar, N. (2010) The effect of pregnancy on energy metabolism, body composition and endothelial function. In: Tsatsoulis, A., Wyckoff, J. and Brown, F.M. (eds.) Diabetes in Women. Series: Contemporary diabetes . Humana Press Inc., pp. 207-222. ISBN 9781603272506

Jarvie, E., Hauguel‑de‑Mouzon, S., Nelson, S.M., Sattar, N., Catalano, P.M., and Freeman, D.J. (2010) Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring. Clinical Science, 119 (3). pp. 123-129. ISSN 0143-5221 (doi:10.1042/CS20090640)

Madigan, J. et al. (2010) Chemokine Scavenger D6 Is Expressed by Trophoblasts and Aids the Survival of Mouse Embryos Transferred into Allogeneic Recipients. Journal of Immunology, 184 (6). pp. 3202-3212. ISSN 0022-1767 (doi:10.4049/jimmunol.0902118)

Nelson, S. M., Stewart, F., Fleming, R., and Freeman, D. J. (2010) Longitudinal assessment of antimullerian hormone during pregnancy-relationship with maternal adiposity, insulin, and adiponectin. Fertility and Sterility, 93 (4). pp. 1356-1358. ISSN 0015-0282 (doi:10.1016/j.fertnstert.2009.07.1676)

Sofat, R. et al. (2010) Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation, 121 (1). pp. 52-62. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.109.865444)

2009

Bernini, F. et al. (2009) European Lipoprotein Club: Report of the 31st ELC Annual Conference, Tutzing, 8–11 September 20. Atherosclerosis, 205 (1). pp. 41-47. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2008.12.003)

Huda, S.S., Freeman, D.J., and Nelson, S.M. (2009) Short and long term strategies for the management of hypertensive disorders of pregnancy. Expert Review of Cardiovascular Therapy, 7 (12). pp. 1581-1594. ISSN 1477-9072 (doi:10.1586/erc.09.147)

Huda, SS, Sattar, NA, and Freeman, D (2009) Lipoprotein metabolism and vascular complications in pregnancy. Clinical Lipidology, 4 (1). pp. 91-102.

Kanagalingam, M.G., Nelson, S., Freeman, D., Ferrell, W.R., Cherry, L.M., Lowe, G.D.O., Greer, I.A., and Sattar, N.A. (2009) Vascular dysfunction and alteration of novel and classic cardiovascular risk factors in mothers of growth restricted offspring. Atherosclerosis, 205 (1). pp. 244-250. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2008.10.006)

Nelson, S, Freeman, D, Sattar, NA, and Lindsay, RS (2009) Erythrocytosis in offspring of mothers with Type 1 diabetes-are factors other than insulin critical determinants? Diabetic Medicine, 26 (9). pp. 887-892. ISSN 0742-3071 (doi:10.1111/j.1464-5491.2009.02797.x )

Sattar, NA et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52 (2). pp. 235-239.

2008

Maclntyre, A., Brouilette, S.W., Lamb, K., Radhakrishnan, K., McGlynn, L.M., Chee, M.M., Parkinson, E.K., Freeman, D., Madhok, R., and Shiels, P.G. (2008) Association of increased telomere lengths in limited scleroderma, with a lack of age-related telomere erosion. Annals of the Rheumatic Diseases, 67 (12). pp. 1780-1782. ISSN 0003-4967 (doi:10.1136/ard.2007.086652)

Sattar, N. et al. (2008) Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. Lancet, 371 (9628). pp. 1927-1935. ISSN 0140-6736 (doi:10.1016/S0140-6736(08)60602-9)

Freeman, D, Tham, K, Brown, EA, Rumley, A, Lowe, GD, and Greer, I (2008) Placental corticotrophin-releasing hormone RNA and microparticles in maternal plasma are not measures of placental shedding of debris: reply to a rebuttal. Journal of Thrombosis and Haemostasis, 6 (10). pp. 1838-1839.

Freeman, D, Tham, K, Brown, EA, Rumley, A, Lowe, GD, and Greer, IA (2008) Fetal corticotrophin-releasing hormone mRNA, but not phosphatidylserine-exposing microparticles, in maternal plasma are associated with factor VII activity in pre-eclampsia. Journal of Thrombosis and Haemostasis, 6 (3). pp. 421-427. ISSN 1538-7933 (doi:10.1111/j.1538-7836.2007.02882.x)

Hofker, M. et al. (2008) European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3–6 Septem. Atherosclerosis, 197 (1). pp. 471-479. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2007.12.022)

Meyer, Barbara, and Freeman, D (2008) Role of omega-3 polyunsaturated fatty acids in pregnancy: need for increasing awareness among women. Agro Food Industry Hi-Tech, 19 (4). pp. 17-19.

Nelson, S., Freeman, D.J., Sattar, N., and Lindsay, R.S. (2008) Role of adiponectin in matching of fetal and placental weight in mothers with type 1 diabetes. Diabetes Care, 31 (6). pp. 1123-1125. ISSN 1935-5548 (doi:10.2337/dc07-2195)

2007

Stewart, F.M., Freeman, D.J., Ramsay, J.E., Greer, I.A., Caslake, M., and Ferrell, W.R. (2007) Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers. Journal of Clinical Endocrinology and Metabolism, 92 (3). pp. 969-975. ISSN 0021-972X (doi:10.1210/jc.2006-2083)

Freeman, D (2007) Genetic factors in vascular disease. In: Greer, I.A., Ginsberg, J. and Forbes, C.D. (eds.) Women's Vascular Health. Hodder Arnold, London, pp. 52-60. ISBN 100340809973

Nelson, S., Freeman, D., Lindsay, R.S., and Sattar, N. (2007) Preeclampsia and screening for cardiovascular disease. BMJ Rapid Response .

Nelson, S.M., Freeman, D.J., Sattar, N., Johnstone, F.D., and Lindsay, R.S. (2007) IGF-1 and leptin associate with fetal HDL cholesterol at birth: Examination in offspring of mothers with type 1 diabetes. Diabetes, 56 . pp. 2705-2709. ISSN 0012-1797 (doi:10.2337/db07-0585)

Nelson, SM, Sattar, N, Freeman, DJ, Walker, JD, and Lindsay, RS (2007) Inflammation and endothelial activation is evident at birth in offspring of mothers with type 1 diabetes. Diabetes, 56 . pp. 2697-2704. (doi:10.2337/db07-0662)

Stewart, F, Rodie, VA, Ramsay, JE, Greer, IA, Freeman, DJ, and Meyer, Barbara (2007) Longitudinal assessment of erythrocyte fatty acid composition throughout pregnancy and post partum. Lipids, 42 . pp. 335-344. (doi:10.1007/s11745-006-3005-5)

2006

Freeman, D (2006) Update on gestational hypertension. Women's Health, 2 (5). pp. 695-698.

2005

Boekholdt, SM et al. (2005) Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment - Individual patient meta-analysis of 13,677 subjects. Circulation, 111 . pp. 278-287. (doi:10.1161/01.CIR.0000153341.46271.40)

Rodie, VA, Young, A, Jordan, F, Sattar, N, Greer, IA, and Freeman, DJ (2005) Human placental peroxisome proliferator-activated receptor delta and gamma expression in healthy pregnancy and in preeclampsia and intrauterine growth restriction. Journal of the Society For Gynecologic Investigation, 12 . pp. 320-329. (doi:10.1016/j.jsgi.2005.03.004)

2004

Freeman, DJ, McManus, F, Brown, EA, Cherry, L, Norrie, J, Ramsay, JE, Clark, P, Walker, ID, Sattar, N, and Greer, IA (2004) Short- and long-term changes in plasma inflammatory markers associated with preeclampsia. Hypertension, 44 . pp. 708-714. (doi:10.1161/01.HYP.0000143849.67254.ca)

Rodie, VA, Caslake, MJ, Stewart, F, Sattar, N, Ramsay, JE, Greer, IA, and Freeman, DJ (2004) Fetal cord plasma lipoprotein status in uncomplicated human pregnancies and in pregnancies complicated by pre-eclampsia and intrauterine growth restriction. Atherosclerosis, 176 . pp. 181-187. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2004.04.026)

Rodie, VA, Freeman, DJ, Sattar, N, and Greer, IA (2004) Pre-eclampsia and cardiovascular disease: metabolic syndrome of pregnancy? Atherosclerosis, 175 . pp. 189-202. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2004.01.038)

Shepherd, J et al. (2004) CHD and diabetes reversing the trend. Doctor, Supple . pp. 1-8.

2003

Clark, P, Freeman, DJ, Streja, E, Sattar, N, Walker, ID, and Greer, IA (2003) The G-to-T point mutation in codon 34 of the factor XIII gene and the risk of pre-eclampsia. Blood Coagulation and Fibrinolysis, 14 . pp. 155-157. ISSN 0957-5235 (doi:10.1097/01.mbc.0000046189.72384.5a)

Freeman, DJ, Samani, NJ, Wilson, V, McMahon, AD, Braund, PS, Cheng, S, Caslake, MJ, Packard, CJ, and Gaffney, D (2003) A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. European Heart Journal, 24 . pp. 1833-1842. (doi:10.1016/j.ehj.2003.07.001)

Shepherd, AJ et al. (2003) Stroke prevention in primary care. Doctor, Supple . pp. 1-8.

Shepherd, J et al. (2003) Obesity, metabolic syndrome and cardiovascular risk. Doctor, Supple . pp. 1-8.

2002

Freeman, D.J., Norrie, J., Caslake, M.J., Gaw, A., Ford, I., Lowe, G.D.O., O'Reilly, D. St. J,, Packard, C.J., and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51 (5). pp. 1596-1600. ISSN 0012-1797 (doi:10.2337/diabetes.51.5.1596)

Freeman, D.J., Norrie, J., Caslake, M.J., Gaw, A., Ford, I., Lowe, G.D.O., O'Reilly, D.S., Packard, C.J., and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51 (5). pp. 1596-1600. ISSN 0012-1797

Shepherd , J.S. et al. (2002) Pragmatic coronary prevention, identifying patients at high risk of coronary heart disease. British Journal of Cardiology, 9 (4). S1-S15. ISSN 0969-6113

2001

Freeman, DJ et al. (2001) Pravastatin and the development of diabetes mellitus - Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. Circulation, 103 (3). pp. 357-362. ISSN 0009-7322

This list was generated on Tue Oct 1 11:58:32 2013 BST.
Jump to: Article | Book Section
Number of items: 52.

Article

Meyer, B.J., Stewart, F.M., Brown, E.A., Cooney, J., Nilsson, S., Olivecrona, G., Ramsay, J.E., Griffin, B.A., Caslake, M.J., and Freeman, D.J. (2013) Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester. Journal of Clinical Endocrinology and Metabolism, 98 (2). pp. 643-652. ISSN 0021-972X (doi:10.1210/jc.2012-3481)

Hodson, L., Neville, M., Chong, M.F.-F., Rogers, I., Huda, S.S., Freeman, D.J., Frayn, K.N., and Fielding, B.A. (2013) Micro-techniques for analysis of human adipose tissue fatty acid composition in dietary studies. Nutrition, Metabolism and Cardiovascular Diseases . ISSN 0939-4753 (doi:10.1016/j.numecd.2012.11.003) (In Press)

Mackenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D., Freeman, D.J., Dominiczak, A.F., McBride, M.W., and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119 (13). pp. 1564-1571. ISSN 1470-0328 (doi:10.1111/1471-0528.12016)

Carty, D.M., Anderson, L.A., Freeman, D.J., Welsh, P.I., Brennand, J.E., Dominiczak, A.F., and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30 (5). pp. 954-959. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328352573b)

Bernini, F. et al. (2012) European lipoprotein club: report of the 34th ELC annual conference, Tutzing, 5–8 September 2011. Atherosclerosis, 221 (1). pp. 287-293. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2011.12.002)

Mackay, V.A. et al. (2012) Preeclampsia is associated with compromized maternal synthesis of long chain polyunsaturated fatty acids leading to offspring deficiency. Hypertension, 60 (4). pp. 1078-1085. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.112.197897)

Bernini, F., Fisher, R., Freeman, D.J., Groen, A., Kalopissis, A., Malle, E., Mulder, M., Niemeier, A., Parini, P., and Hansen, A.T. (2011) Report of the 33rd Annual Conference of the European Lipoprotein Club, Tutzing, 6–9 September 2010. Atherosclerosis, 215 (1). pp. 249-255. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2010.12.002)

Freeman, D. et al. (2011) Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). BMC Geriatrics, 11 (8). ISSN 1471-2318 (doi:10.1186/1471-2318-11-8)

Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375 (9716). pp. 735-742. ISSN 0140-6736 (doi:10.1016/S0140-6736(09)61965-6)

Fisher, R. et al. (2010) European Lipoprotein Club: Report of the 32nd ELC Annual Conference, Tutzing, 7–10 September 2009. Atherosclerosis, 210 (2). pp. 680-686. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2009.12.038)

Freeman, D.J. (2010) Effects of maternal obesity on fetal growth and body composition: implications for programming and future health. Seminars in Fetal and Neonatal Medicine, 15 (2). pp. 113-118. ISSN 1744-165X (doi:10.1016/j.siny.2009.09.001 Univ Glasgow, Western Infirm, Fac Med, Glasgow G11 6NT, Lanark, Scotland.)

Jarvie, E., Hauguel‑de‑Mouzon, S., Nelson, S.M., Sattar, N., Catalano, P.M., and Freeman, D.J. (2010) Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring. Clinical Science, 119 (3). pp. 123-129. ISSN 0143-5221 (doi:10.1042/CS20090640)

Madigan, J. et al. (2010) Chemokine Scavenger D6 Is Expressed by Trophoblasts and Aids the Survival of Mouse Embryos Transferred into Allogeneic Recipients. Journal of Immunology, 184 (6). pp. 3202-3212. ISSN 0022-1767 (doi:10.4049/jimmunol.0902118)

Nelson, S. M., Stewart, F., Fleming, R., and Freeman, D. J. (2010) Longitudinal assessment of antimullerian hormone during pregnancy-relationship with maternal adiposity, insulin, and adiponectin. Fertility and Sterility, 93 (4). pp. 1356-1358. ISSN 0015-0282 (doi:10.1016/j.fertnstert.2009.07.1676)

Sofat, R. et al. (2010) Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation, 121 (1). pp. 52-62. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.109.865444)

Bernini, F. et al. (2009) European Lipoprotein Club: Report of the 31st ELC Annual Conference, Tutzing, 8–11 September 20. Atherosclerosis, 205 (1). pp. 41-47. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2008.12.003)

Huda, S.S., Freeman, D.J., and Nelson, S.M. (2009) Short and long term strategies for the management of hypertensive disorders of pregnancy. Expert Review of Cardiovascular Therapy, 7 (12). pp. 1581-1594. ISSN 1477-9072 (doi:10.1586/erc.09.147)

Huda, SS, Sattar, NA, and Freeman, D (2009) Lipoprotein metabolism and vascular complications in pregnancy. Clinical Lipidology, 4 (1). pp. 91-102.

Kanagalingam, M.G., Nelson, S., Freeman, D., Ferrell, W.R., Cherry, L.M., Lowe, G.D.O., Greer, I.A., and Sattar, N.A. (2009) Vascular dysfunction and alteration of novel and classic cardiovascular risk factors in mothers of growth restricted offspring. Atherosclerosis, 205 (1). pp. 244-250. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2008.10.006)

Nelson, S, Freeman, D, Sattar, NA, and Lindsay, RS (2009) Erythrocytosis in offspring of mothers with Type 1 diabetes-are factors other than insulin critical determinants? Diabetic Medicine, 26 (9). pp. 887-892. ISSN 0742-3071 (doi:10.1111/j.1464-5491.2009.02797.x )

Sattar, NA et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52 (2). pp. 235-239.

Maclntyre, A., Brouilette, S.W., Lamb, K., Radhakrishnan, K., McGlynn, L.M., Chee, M.M., Parkinson, E.K., Freeman, D., Madhok, R., and Shiels, P.G. (2008) Association of increased telomere lengths in limited scleroderma, with a lack of age-related telomere erosion. Annals of the Rheumatic Diseases, 67 (12). pp. 1780-1782. ISSN 0003-4967 (doi:10.1136/ard.2007.086652)

Sattar, N. et al. (2008) Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. Lancet, 371 (9628). pp. 1927-1935. ISSN 0140-6736 (doi:10.1016/S0140-6736(08)60602-9)

Freeman, D, Tham, K, Brown, EA, Rumley, A, Lowe, GD, and Greer, I (2008) Placental corticotrophin-releasing hormone RNA and microparticles in maternal plasma are not measures of placental shedding of debris: reply to a rebuttal. Journal of Thrombosis and Haemostasis, 6 (10). pp. 1838-1839.

Freeman, D, Tham, K, Brown, EA, Rumley, A, Lowe, GD, and Greer, IA (2008) Fetal corticotrophin-releasing hormone mRNA, but not phosphatidylserine-exposing microparticles, in maternal plasma are associated with factor VII activity in pre-eclampsia. Journal of Thrombosis and Haemostasis, 6 (3). pp. 421-427. ISSN 1538-7933 (doi:10.1111/j.1538-7836.2007.02882.x)

Hofker, M. et al. (2008) European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3–6 Septem. Atherosclerosis, 197 (1). pp. 471-479. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2007.12.022)

Meyer, Barbara, and Freeman, D (2008) Role of omega-3 polyunsaturated fatty acids in pregnancy: need for increasing awareness among women. Agro Food Industry Hi-Tech, 19 (4). pp. 17-19.

Nelson, S., Freeman, D.J., Sattar, N., and Lindsay, R.S. (2008) Role of adiponectin in matching of fetal and placental weight in mothers with type 1 diabetes. Diabetes Care, 31 (6). pp. 1123-1125. ISSN 1935-5548 (doi:10.2337/dc07-2195)

Stewart, F.M., Freeman, D.J., Ramsay, J.E., Greer, I.A., Caslake, M., and Ferrell, W.R. (2007) Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers. Journal of Clinical Endocrinology and Metabolism, 92 (3). pp. 969-975. ISSN 0021-972X (doi:10.1210/jc.2006-2083)

Nelson, S., Freeman, D., Lindsay, R.S., and Sattar, N. (2007) Preeclampsia and screening for cardiovascular disease. BMJ Rapid Response .

Nelson, S.M., Freeman, D.J., Sattar, N., Johnstone, F.D., and Lindsay, R.S. (2007) IGF-1 and leptin associate with fetal HDL cholesterol at birth: Examination in offspring of mothers with type 1 diabetes. Diabetes, 56 . pp. 2705-2709. ISSN 0012-1797 (doi:10.2337/db07-0585)

Nelson, SM, Sattar, N, Freeman, DJ, Walker, JD, and Lindsay, RS (2007) Inflammation and endothelial activation is evident at birth in offspring of mothers with type 1 diabetes. Diabetes, 56 . pp. 2697-2704. (doi:10.2337/db07-0662)

Stewart, F, Rodie, VA, Ramsay, JE, Greer, IA, Freeman, DJ, and Meyer, Barbara (2007) Longitudinal assessment of erythrocyte fatty acid composition throughout pregnancy and post partum. Lipids, 42 . pp. 335-344. (doi:10.1007/s11745-006-3005-5)

Freeman, D (2006) Update on gestational hypertension. Women's Health, 2 (5). pp. 695-698.

Boekholdt, SM et al. (2005) Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment - Individual patient meta-analysis of 13,677 subjects. Circulation, 111 . pp. 278-287. (doi:10.1161/01.CIR.0000153341.46271.40)

Rodie, VA, Young, A, Jordan, F, Sattar, N, Greer, IA, and Freeman, DJ (2005) Human placental peroxisome proliferator-activated receptor delta and gamma expression in healthy pregnancy and in preeclampsia and intrauterine growth restriction. Journal of the Society For Gynecologic Investigation, 12 . pp. 320-329. (doi:10.1016/j.jsgi.2005.03.004)

Freeman, DJ, McManus, F, Brown, EA, Cherry, L, Norrie, J, Ramsay, JE, Clark, P, Walker, ID, Sattar, N, and Greer, IA (2004) Short- and long-term changes in plasma inflammatory markers associated with preeclampsia. Hypertension, 44 . pp. 708-714. (doi:10.1161/01.HYP.0000143849.67254.ca)

Rodie, VA, Caslake, MJ, Stewart, F, Sattar, N, Ramsay, JE, Greer, IA, and Freeman, DJ (2004) Fetal cord plasma lipoprotein status in uncomplicated human pregnancies and in pregnancies complicated by pre-eclampsia and intrauterine growth restriction. Atherosclerosis, 176 . pp. 181-187. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2004.04.026)

Rodie, VA, Freeman, DJ, Sattar, N, and Greer, IA (2004) Pre-eclampsia and cardiovascular disease: metabolic syndrome of pregnancy? Atherosclerosis, 175 . pp. 189-202. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2004.01.038)

Shepherd, J et al. (2004) CHD and diabetes reversing the trend. Doctor, Supple . pp. 1-8.

Clark, P, Freeman, DJ, Streja, E, Sattar, N, Walker, ID, and Greer, IA (2003) The G-to-T point mutation in codon 34 of the factor XIII gene and the risk of pre-eclampsia. Blood Coagulation and Fibrinolysis, 14 . pp. 155-157. ISSN 0957-5235 (doi:10.1097/01.mbc.0000046189.72384.5a)

Freeman, DJ, Samani, NJ, Wilson, V, McMahon, AD, Braund, PS, Cheng, S, Caslake, MJ, Packard, CJ, and Gaffney, D (2003) A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. European Heart Journal, 24 . pp. 1833-1842. (doi:10.1016/j.ehj.2003.07.001)

Shepherd, AJ et al. (2003) Stroke prevention in primary care. Doctor, Supple . pp. 1-8.

Shepherd, J et al. (2003) Obesity, metabolic syndrome and cardiovascular risk. Doctor, Supple . pp. 1-8.

Freeman, D.J., Norrie, J., Caslake, M.J., Gaw, A., Ford, I., Lowe, G.D.O., O'Reilly, D. St. J,, Packard, C.J., and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51 (5). pp. 1596-1600. ISSN 0012-1797 (doi:10.2337/diabetes.51.5.1596)

Freeman, D.J., Norrie, J., Caslake, M.J., Gaw, A., Ford, I., Lowe, G.D.O., O'Reilly, D.S., Packard, C.J., and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51 (5). pp. 1596-1600. ISSN 0012-1797

Shepherd , J.S. et al. (2002) Pragmatic coronary prevention, identifying patients at high risk of coronary heart disease. British Journal of Cardiology, 9 (4). S1-S15. ISSN 0969-6113

Freeman, DJ et al. (2001) Pravastatin and the development of diabetes mellitus - Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. Circulation, 103 (3). pp. 357-362. ISSN 0009-7322

Book Section

Sattar, N., and Freeman, D.J. (2012) Potential mechanisms contributing to gestational diabetes and pre-eclampsia in the obese woman. In: Gillman, M.W. and Poston, L. (eds.) Maternal Obesity. Series: Cambridge medicine . Cambridge University Press, Cambridge, UK, pp. 45-55. ISBN 978107003965

Sattar, N., and Freeman, D.J. (2012) Potential mechanisms contributing to gestational diabetes and preeclampsia in the obese woman. In: Gillman, M.W. and Poston, L. (eds.) Maternal Obesity. Cambridge University Press . ISBN 9781107003965

Freeman, D.J., and Sattar, N. (2010) The effect of pregnancy on energy metabolism, body composition and endothelial function. In: Tsatsoulis, A., Wyckoff, J. and Brown, F.M. (eds.) Diabetes in Women. Series: Contemporary diabetes . Humana Press Inc., pp. 207-222. ISBN 9781603272506

Freeman, D (2007) Genetic factors in vascular disease. In: Greer, I.A., Ginsberg, J. and Forbes, C.D. (eds.) Women's Vascular Health. Hodder Arnold, London, pp. 52-60. ISBN 100340809973

This list was generated on Tue Oct 1 11:58:32 2013 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Study visit to Australia - Early Pregnancy Study
    Harold Hyam Wingate Foundation
    2010 - 2010
     
  • Early pregnancy mobilisation of fatty acids
    Carnegie UK Trust
    2010 - 2011
     
  • Maternal lipotoxic response in obese pregnancy
    Wellbeing of Women
    2010 - 2012
     
  • The intrauterine environment and differences in adiposity and insulin resistance between South Asian and European populations
    British Heart Foundation
    2009 - 2011
     
  • Early pregnancy metabolic and inflammatory changes and their relationship to successful pregnancy
    Wellbeing of Women
    2007 - 2010
     
  • International exchange visit to Australia September 2005
    Royal Society of Edinburgh
    2005 - 2005
     
  • Risk factors for the development of incident thrombotic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Chest, Heart & Stroke, Scotland
    2005 - 2006
     
  • An investigation of the role of the chemokine receptor D6 in placental dysfunction
    Scottish Hospital Endowments Research Trust
    2005 - 2007
     
  • Adipocyte lipolysis as a candidate pathway in the pathogenesis of pre-eclampsia
    British Heart Foundation
    2004 - 2008
     
  • Maternal and fetal dyslipidaemia in polycystic ovarian syndrome pregnancy
    The Future Forum
    2004 - 2005
     
  • Longitudinal assessment of vascular function throughout pregnancy and the puerperium - relationship of maternal body fat distribution to...
    British Medical Association
    2003 - 2006
     
  • Does low birth weight pregnancy signal markedly increased maternal cardiovascular risk
    Chest, Heart & Stroke, Scotland
    2003 - 2004
     
  • Lipocortin 1 - modulation of molecular mechanisms of inflammation in atherosclerosis
    British Heart Foundation
    2003 - 2005
     
  • Is there a link between inflammation and insulin resistance in pre-eclampsia?
    Scottish Executive Health Department
    2003 - 2004
     

Editorial Board

  • 2000 - 2007: Atherosclerosis - Associate Editor
  • - ongoing: Clinical Science - Editorial Board and Associate Editor

Invited International Presentations

  • 2011: American Diabetes Association - Keynote speaker
  • 2011: Australian Diabetes in Pregnancy Society (ADIPS) - Keynote speaker
  • 2011: New Zealand Maternal Fetal Medicine Network - Keynote speaker
  • 2010: International Association of the Diabetes and Pregnancy Study Groups (IADPSG) - Keynote speaker
  • 2008: International Society for the Study of Hypertension in Pregnancy (ISSHP) - Keynote speaker

Professional Learned Society

  • 2008 - ongoing: University of Wollongong, Australia - Visiting Senior Fellow
  • 2007 - 2011: European Lipoprotein Club - Treasurer