2013

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow & Metabolism . ISSN 0271-678X (doi:10.1038/jcbfm.2013.14) (In Press)

2012

Reid, E., Graham, D., Lopez-Gonzalez, M.R., Holmes, W.M., Macrae, I.M., and McCabe, C. (2012) Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. Journal of Cerebral Blood Flow & Metabolism, 32 (9). pp. 1765-1777. ISSN 0271-678X (doi:10.1038/jcbfm.2012.69)

Flores, M., Work, L.M., Douglas, K., Denby, L., Dominiczak, A.F., Graham, D., and Nicklin, S.A. (2012) Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension, 59 (2). pp. 300-307. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.177485)

Flores-Munoz, M., Work, L.M., Douglas, K., Denby, L., Dominiczak, A.F., Graham, D., and Nicklin, S.A. (2012) Angiotensin (1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension, 59 (2). pp. 300-3007. ISSN 0194-911X

Xu, H. et al. (2012) Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension. Cardiovascular Research, 96 (3). pp. 552-560. ISSN 0008-6363 (doi:10.1093/cvr/cvs273)

2011

Bailey, E.L., Wardlaw, J.M., Graham, D., Dominiczak, A.F., Sudlow, C.L.M., and Smith, C. (2011) Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathology and Applied Neurobiology, 37 (7). pp. 711-726. ISSN 0305-1846 (doi:10.1111/j.1365-2990.2011.01170.x)

Yogi, A., Callera, G.E., Aranha, A.B., Antunes, T.T., Graham, D., McBride, M., Dominiczak, A., and Touyz, R.M. (2011) Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells: Upregulation in Hypertension. Hypertension, 57 (4). pp. 809-819. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.110.162719)

2010

Greig, J.A., Shirley, R., Graham, D., Denby, L., Dominiczak, A.F., Work, L.M., and Baker, A. (2010) Vascular-targeting anti-oxidant therapy in a model of hypertension and stroke. Journal of Cardiovascular Pharmacology, 56 (6). pp. 642-650. ISSN 0160-2446 (doi:10.1097/FJC.0b013e3181f8f19f)

Delles, C., McBride, M.W., Graham, D., Padmanabhan, S., and Dominiczak, A.F. (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1802 (12). pp. 1299-1308. ISSN 0925-4439 (doi:10.1016/j.bbadis.2009.12.006)

Graham, D., Koh-Tan, H. H. C., and Dominiczak, A. F. (2010) Reduced renal glutathione S-transferase mu type 1 expression in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 28 (3). p. 634. ISSN 0263-6352 (doi:10.1097/HJH.0b013e328336902d)

Greig, J.A., Shirley, R., Graham, D., Denby, L., Dominiczak, A.F., Work, L.M., and Baker, A.H. (2010) Vascular-Targeting Antioxidant Therapy in a Model of Hypertension and Stroke. Journal of Cardiovascular Pharmacology, 56 (6). pp. 642-650. ISSN 0160-2446 (doi:10.1097/FJC.0b013e3181f8f19f)

Hopcroft, L.E.M., McBride, M.W., Harris, K.J., Sampson, A.K., McClure, J.D., Graham, D., Young, G., Holyoake, T.L., Girolami, M.A., and Dominiczak, A.F. (2010) Predictive response-relevant clustering of expression data provides insights into disease processes. Nucleic Acids Research, 38 (20). pp. 6831-6840. ISSN 0305-1048 (doi:10.1093/nar/gkq550)

McBride, M., Hopcroft, L., Harris, K., McClure, J., Graham, D., Girolami, M., and Dominiczak, M. (2010) Insights into Salt-Sensitive Hypertension Using Response-Relevant Clustering. In: 20th Annual Meeting of the European Society of Hypertension, 18-21 June, Oslo, Norway.

McCabe, C., Gallagher, L., Macrae, I.M., Gsell, W., Graham, D., and Dominiczak, A.F. (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41 (4). E198-E199. ISSN 0039-2499 (doi:10.1161/STROKEAHA.109.575704)

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6 (10). e1001177. ISSN 1553-7390 (doi:10.1371/journal.pgen.1001177)

2009

McCabe, C., Gallagher, L., Gsell, W., Graham, D., Dominiczak, A.F., and Macrae, I.M. (2009) Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke, 40 (12). pp. 3864-3868. ISSN 0039-2499 (doi:10.1161/STROKEAHA.109.559021)

Graham, D., Huynh, N.N., Hamilton, C.A., Beattie, E.C., Smith, R.A.J., Cocheme, H.M., Murphy, M.P., and Dominiczak, A.F. (2009) Mitochondria-targeted antioxidant MitoQ(10) improves endothelial function and attenuates cardiac hypertrophy. Hypertension, 54 (2). 322-U233. ISSN 0194-911X (doi:10.1161/​HYPERTENSIONAHA.109.130351)

Johannesson, M et al. (2009) A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: The NIH heterogeneous stock. Genome Research, 19 (1). pp. 150-158. ISSN 1088-9051 (doi:10.1101/gr.081497.108 )

Koh-Tan, HC, Graham, D, Hamilton, CA, Nicoll, G, Fields, L, McBride, MW, Young, BC, Young, B, and Dominiczak, AF (2009) Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of Hypertension, 27 (8). pp. 1575-1584. ISSN 0263-6352 (doi:10.1097/HJH.0b013e32832cc5a1 )

Masson, R. et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension, 53 (4). pp. 694-700. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.108.122333)

Xu, A., Chamberlain, J., Francis, S., Brookes, Z., Shaw, G., Graham, D., Alp, N.J., Dower, S., and Crossman, D.C. (2009) Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PLoS ONE, 4 (4). e5073. ISSN 1932-6203 (doi:10.1371/journal.pone.0005073)

2008

Miller, WH, Graham, D, Douglas, K, MacKenzie, RM, and Dominiczak, AF (2008) Metabolic phenotypes in SHRSP and chromosome 2 congenic strains. Journal of Human Hypertension, 22 (10). pp. 736-737. ISSN 0950-9240

Miller, WH, Graham, D, Douglas, K, Mackenzie, R, Huynh, N, and Dominiczak, AF (2008) Characterisation of metabolic phenotypes in the SHRSP using chromosome 2 congenic strains. Journal of Hypertension, 26 (Suppl.). S340-S341. ISSN 0263-6352

Tian, T., McBride, M.W., Graham, D., Touyz, R., and Dominiczak, A.F. (2008) A systems biology approach for the sphingosine-1-phosphate signal transduction in vascular smooth muscle cell. Journal of Hypertension, 26 (Suppl.). S148-S148. ISSN 0263-6352

Tonyz, R, Aranha, A, Yogi, A, Graham, D, McBride, MW, Callera, G, Montezano, A, Coimbra, T, and Dominiczak, AF (2008) Increased vascular sphingosine-1-phosphate signaling in SHRSP is due to post-receptor mechanisms. Journal of Hypertension, 26 (Suppl.). S329-S329. ISSN 0263-6352

2007

Graham, D. et al. (2007) Candidate genes that determine response to salt in the stroke-prone spontaneously hypertensive rat - Congenic analysis. Hypertension, 50 . pp. 1134-1141. (doi:10.1161/HYPERTENSIONAHA.107.095349)

2004

McBride, M.W., Charchar, F.J., Graham, D., Miller, W.H., Strahorn, P., Carr, F.J., and Dominiczak, A.F. (2004) Functional genomics in rodent models of hypertension. Journal of Physiology, 554 . pp. 56-63. ISSN 0022-3751 (doi:10.1113/jphysiol.2003.049361)

Denby, L., Work, L.M., Graham, D., Hsu, C., Von Seggern, D.J., Nicklin, S.A., and Baker, A.H. (2004) Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. Human Gene Therapy, 15 (11). pp. 1054-1064. ISSN 1043-0342