- Senior Lecturer (Institute of Cardiovascular and Medical Sciences)
- Associate Academic (School of Veterinary Medicine)
Dr. Christopher Loughrey is a veterinary surgeon and principal investigator within the Glasgow Cardiovascular Research Centre. His laboratory utilises a wide range of experimental techniques to investigate heart function at the level of the molecule, cell, organ and whole animal. This integrative approach provides the opportunity to study abnormal alterations of gene and protein expression/function and in turn how these changes influence whole heart function during cardiac disease. Dr. Loughrey’s laboratory has practical expertise in a number of methodologies including: confocal microscopy, single cell electrophysiology, fluorescence measurements/imaging, Western blotting, PCR, whole heart techniques (Langendorff perfusion and working heart preparations) and in vivo cardiovascular measurements/micro-surgery (e.g. intra-ventricular pressure-volume measurements, electrocardiography and a mouse model of myocardial infarction). These techniques are used in a number of projects which are on-going within the laboratory which aim to inform the development of therapeutic strategies to treat cardiac disease in animals and humans.