2013

Baker, A.H., and Delles, C. (2013) Is microRNA-376c a biomarker or mediator of preeclampsia? Hypertension, 61 (4). pp. 767-769. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.111.00087)

Bradshaw, A.C., Coughlan, L., Miller, A.M., Nicklin, S.A., and Baker, A.H. (2013) Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses. Journal of Controlled Release, 164 (3). pp. 394-402. ISSN 0168-3659 (doi:10.1016/j.jconrel.2012.05.025)

Kane, N., and Baker, A. (2013) Pluripotent stem cell-derived endothelial cells for vascular disease therapy. International Drug Discovery . ISSN 2150-4792 (In Press)

McDonald, R.A. et al. (2013) miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation. European Heart Journal . ISSN 0195-668X (doi:10.1093/eurheartj/eht105) (In Press)

2012

Chick, H.E. et al. (2012) Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy, 23 (12). pp. 1247-1257. ISSN 1043-0342 (doi:10.1089/hum.2012.042)

Kaupisch, A., Kennedy, L., Stelmanis, V., Tye, B., Kane, N.M., Mountford, J.C., Courtney, A., and Baker, A.H. (2012) Derivation of vascular endothelial cells from human embryonic stem cells under GMP-compliant conditions: towards clinical studies in ischaemic disease. Journal of Cardiovascular Translational Research, 5 (5). pp. 605-617. ISSN 1937-5387 (doi:10.1007/s12265-012-9379-2)

Robertson, K.E., McDonald, R.A., Oldroyd, K.G., Nicklin, S.A., and Baker, A.H. (2012) Prevention of coronary in-stent restenosis and vein graft failure: Does vascular gene therapy have a role? Pharmacology and Therapeutics, 136 (1). pp. 23-34. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2012.07.002)

Robinson, H.C., and Baker, A.H. (2012) How do microRNAs affect vascular smooth muscle cell biology? Current Opinion in Lipidology, 23 (5). pp. 405-411. ISSN 0957-9672 (doi:10.1097/MOL.0b013e32835719a1)

Coughlan, L., Vallath, S., Gros, A., Giménez-Alejandre, M., Van Rooijen, N., Thomas, G.J., Baker, A.H., Cascalló, M., Alemany, R., and Hart, I.R. (2012) Combined fiber modifications both to target αvβ6 and detarget the coxsackievirus–adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5. Human Gene Therapy, 23 (9). pp. 960-979. ISSN 1043-0342 (doi:10.1089/hum.2011.218)

Baker, A.H. (2012) Spotlight: Andrew Baker, PhD, FAHA, FESC, FRSE: "A strategy of short-term genetic engineering prevented long-term pathological processes in the vein graft". Circulation, 125 (21). F121-F123. ISSN 0009-7322 (doi:10.1161/CIR.0b013e31825e771f )

White, K., Kane, N.M., Milligan, G., and Baker, A.H. (2012) The role of miRNA in stem cell pluripotency and commitment to the vascular endothelial lineage. Microcirculation, 19 (3). pp. 196-207. ISSN 1073-9688 (doi:10.1111/j.1549-8719.2012.00161.x)

Duffy, M.R., Parker, A.L., Bradshaw, A.C., and Baker, A.H. (2012) Manipulation of adenovirus interactions with host factors for gene therapy applications. Nanomedicine, 7 (2). pp. 271-288. ISSN 1743-5889 (doi:10.2217/nnm.11.186)

Alba, R., Bradshaw, A.C., Mestre-Francés, N., Verdier, J.-M., Henaff, D., and Baker, A.H. (2012) Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus). Gene Therapy, 19 (1). pp. 109-113. ISSN 0969-7128 (doi:10.1038/gt.2011.87)

Caruso, P. et al. (2012) A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circulation Research, 111 (3). pp. 290-300. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.112.267591)

Coughlan, L. et al. (2012) Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery. Molecular Therapy, 20 (12). pp. 2268-2281. ISSN 1525-0016 (doi:10.1038/mt.2012.162)

Coughlan, Lynda, Vallath, S., Gros, A., Giménez-Alejandre, M., Van Rooijen, N., Thomas, G.J., Baker, A.H., Cascalló, M., Alemany, R., and Hart, I.R. (2012) Combined fiber modifications both to target αvβ6 and detarget the coxsackievirus–adenovirus receptor improve virus toxicity profilesIn vivobut fail to improve antitumoral efficacy relative to adenovirus serotype 5. Human Gene Therapy, 23 (9). pp. 960-979. ISSN 1043-0342 (doi:10.1089/hum.2011.218)

Duffy, M.R., Kalkman, E., and Baker, A.H. (2012) Identification of a novel small molecule inhibitor of FX-mediated Ad5 gene transfer for gene therapy applications. Molecular Therapy, 20 (S1). S117-S117. ISSN 1525-0016 (doi:10.1038/mt.2012.86)

Kane, N.M. et al. (2012) Role of MicroRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. Stem Cells, 30 (4). pp. 643-654. ISSN 1066-5099 (doi:10.1002/stem.1026)

McDonald, R.A., Hata, A., MacLean, M.R., Morrell, N.W., and Baker, A.H. (2012) MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling. Cardiovascular Research, 93 (4). pp. 594-604. ISSN 0008-6363 (doi:10.1093/cvr/cvr299)

Morecroft, I., White, K., Caruso, P., Nilsen, M., Loughlin, L., Alba, R., Reynolds, P.N., Danilov, S.M., Baker, A.H., and MacLean, M.R. (2012) Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension. Molecular Therapy, 20 (8). pp. 1516-1528. ISSN 1525-0016 (doi:10.1038/mt.2012.70)

Rahim, A.A. et al. (2012) In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression. Gene Therapy, 19 (9). pp. 936-946. ISSN 0969-7128 (doi:10.1038/gt.2011.157)

2011

Ialenti, A. et al. (2011) Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries. Arteriosclerosis, Thrombosis and Vascular Biology, 31 (11). pp. 2448-2454. ISSN 1079-5642 (doi:10.1161/ATVBAHA.111.230078)

Duffy, M.R., Bradshaw, A.C., Parker, A.L., McVey, J.H., and Baker, A.H. (2011) A cluster of basic amino acids in the factor X serine protease mediate surface attachment of adenovirus/FX complexes. Journal of Virology, 85 (20). pp. 10914-10919. ISSN 0022-538X (doi:10.1128/JVI.05382-11)

Kane, N., Xiao, Q., Baker, A., Zhenling, L., Qingbo, X., and Emanueli, C. (2011) Pluripotent stem cell differentiation into vascular cells: a novel technology with promises for vascular re(generation). Pharmacology and Therapeutics, 129 (1). pp. 29-49. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2010.10.004)

Baker, A.H. (2011) MicroRNA 21 "Shapes" Vascular Smooth Muscle Behavior Through Regulating Tropomyosin 1. Arteriosclerosis, Thrombosis and Vascular Biology, 31 (9). pp. 1941-1942. ISSN 1079-5642 (doi:10.1161/ATVBAHA.111.231985)

Caporali, A. et al. (2011) Deregulation of microRNA-503 Contributes to Diabetes Mellitus-Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia. Circulation, 123 (3). pp. 282-291. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.110.952325)

Denby, L. et al. (2011) miR-21 and miR-214 are consistently modulated during renal injury in rodent models. American Journal of Pathology, 179 (2). pp. 661-672. ISSN 0002-9440 (doi:10.1016/j.ajpath.2011.04.021)

George, S. J., Wan, S., Hu, J., MacDonald, R., Johnson, J. L., and Baker, A.H. (2011) Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy. Circulation, 124 (11_sup). S135-S142. ISSN 0009-7322 (doi:10.1161/CIRCULATIONAHA.110.012732)

Howard, L., Kane, N.M., Milligan, G., and Baker, A.H. (2011) MicroRNAs regulating cell pluripotency and vascular differentiation. Vascular Pharmacology, 55 (4). pp. 69-78. ISSN 1537-1891 (doi:10.1016/j.vph.2011.08.002)

White, K., Loughlin, L., Maqbool, Z., Nilsen, M., McClure, J., Dempsie, Y., Baker, A.H., and MacLean, M.R. (2011) The serotonin transporter, gender and hypoxia: Microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. Physiological Genomics, 43 (8). pp. 417-437. ISSN 1094-8341 (doi:10.1152/physiolgenomics.00249.2010)

2010

Greig, J.A., Shirley, R., Graham, D., Denby, L., Dominiczak, A.F., Work, L.M., and Baker, A. (2010) Vascular-targeting anti-oxidant therapy in a model of hypertension and stroke. Journal of Cardiovascular Pharmacology, 56 (6). pp. 642-650. ISSN 0160-2446 (doi:10.1097/FJC.0b013e3181f8f19f)

Othman, M. et al. (2010) Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease. Blood, 116 (18). pp. 3645-3652. ISSN 0006-4971 (doi:10.1182/blood-2009-12-261131)

Othman, M. et al. (2010) Functional characterization of a 13 bp deletion (-1522_-1510del) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease. Blood, 116 (18). pp. 3645-3652. ISSN 0006-4971 (doi:10.1182/blood-2009-12-261131 )

Alba, R. et al. (2010) Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood, 14 (116). pp. 2656-2664. ISSN 0006-4971 (doi:10.1182/blood-2009-12-260026)

Burton, P. et al. (2010) Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells. Biochemical Society Transactions, 38 (4). pp. 1058-1061. ISSN 0300-5127 (doi:10.1042/BST0381058)

Kane, N.M., Meloni, M., Spencer, H.L., Craig, M.A., Strehl, R., Milligan, G., Houslay, M.D., Mountford, J.C., Emanueli, C., and Baker, A.H. (2010) Derivation of endothelial cells from human embryonic stem cells by directed differentiation: analysis of microRNA and angiogenesis in vitro and in vivo. Arteriosclerosis, Thrombosis and Vascular Biology, 30 (7). pp. 1389-1397. ISSN 1079-5642 (doi:10.1161/ATVBAHA.110.204800)

Caruso, P. et al. (2010) Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline. Arteriosclerosis, Thrombosis and Vascular Biology, 30 (4). pp. 716-723. ISSN 1079-5642 (doi:10.1161/ATVBAHA.109.202028)

Shin, S.Y., Kim, J.H., Baker, A.H., Lim, Y., and Lee, Y.H. (2010) Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor α. Molecular Cancer Research, 8 (4). pp. 507-519. ISSN 1541-7786 (doi:10.1158/1541-7786.MCR-09-0454)

Balestrieri, M. L. et al. (2010) Therapeutic angiogenesis in diabetic apolipoprotein E-deficient mice using bone marrow cells, functional hemangioblasts and metabolic intervention. Atherosclerosis, 209 (2). pp. 403-414. ISSN 0021-9150 (doi:10.1016/j.atherosclerosis.2009.10.022)

Bradshaw, A.C., Parker, A.L., Duffy, M.R., Coughlan, L., van Rooijen, N., Kahari, V.M., Nicklin, S.A., and Baker, A.H. (2010) Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X. PLoS Pathogens, 6 (10). e1001142. ISSN 1553-7366 (doi:10.1371/journal.ppat.1001142)

Burton, P. et al. (2010) Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells. Biochemical Journal, 432 (3). pp. 575-584. ISSN 0264-6021 (doi:10.1042/BJ20100726)

Coughlan, L., Alba, R., Parker, A.L., Bradshaw, A.C., Mcneish, I.A., Nicklin, S., and Baker, A. (2010) Tropism-modification strategies for targeted gene delivery using adenoviral vectors. Viruses, 2 (10). pp. 2290-2355. ISSN 1999-4915 (doi:10.3390/v2102290)

Greig, J.A., Shirley, R., Graham, D., Denby, L., Dominiczak, A.F., Work, L.M., and Baker, A.H. (2010) Vascular-Targeting Antioxidant Therapy in a Model of Hypertension and Stroke. Journal of Cardiovascular Pharmacology, 56 (6). pp. 642-650. ISSN 0160-2446 (doi:10.1097/FJC.0b013e3181f8f19f)

Kallio, J.P., Hopkins-Donaldson, S., Baker, A.H., and Kähäri, V.M. (2010) TIMP-3 promotes apoptosis in nonadherent small cell lung carcinoma cells lacking functional death receptor pathway. International Journal of Cancer, 128 (4). pp. 991-996. ISSN 00207136 (doi:10.1002/ijc.25404)

Kane, N.M. et al. (2010) Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors. Molecular Therapy, 18 (12). pp. 2139-2145. ISSN 1525-0016 (doi:10.1038/mt.2010.231)

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6 (10). e1001177. ISSN 1553-7390 (doi:10.1371/journal.pgen.1001177)

Shin, S.Y., Kim, J.H., Baker, A., Lim, Y., and Lee, Y. (2010) Transcription Factor Egr-1 Is Essential for Maximal Matrix Metalloproteinase-9 Transcription by Tumor Necrosis Factor alpha. Molecular Cancer Research, 8 (4). pp. 507-519. ISSN 1541-7786 (doi:10.1158/1541-7786.MCR-09-0454)

2009

Alba, R. et al. (2009) Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood, 114 (5). pp. 965-971. ISSN 0006-4971 (doi:10.1182/blood-2009-03-208835)

Terashima, T., Oka, K., Kritz, A.B., Kojima, H., Baker, A.H., and Chan, L. (2009) DRG-targeted helper-dependent adenoviruses mediate selective gene delivery for therapeutic rescue of sensory neuronopathies in mice. Journal of Clinical Investigation, 119 (7). pp. 2100-2112. ISSN 0021-9738 (doi:10.1172/JCI39038)

Nicol, C.G., Denby, L., Lopez-Franco, O., Masson, R., Halliday, C.A., Nicklin, S.A., Kritz, A., Work, L.M., and Baker, A.H. (2009) Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature. Febs Letters, 583 (12). pp. 2100-2107. ISSN 0014-5793 (doi:10.1016/j.febslet.2009.05.037)

Diaconu, I. et al. (2009) Serotype chimeric and fiber-mutated adenovirus Ad5/19p-HIT for targeting renal cancer and untargeting the liver. Human Gene Therapy, 20 (6). pp. 611-620. ISSN 1043-0342 (doi:10.1089/hum.2008.108)

Liu, Y., Wang, H.J., Yumul, R., Gao, W.T., Gambotto, A., Morita, T., Baker, A.H., Shayakhmetov, D., and Lieber, A. (2009) Transduction of liver metastases after intravenous injection of Ad5/35 or Ad35 vectors with and without factor X-binding protein pretreatment. Human Gene Therapy, 20 (6). pp. 621-629. ISSN 1043-0342 (doi:10.1089/hum.2008.142)

Parker, A.L., Waddington, S.N., Buckley, S.M.K., Custers, J., Havenga, M.J.E., van Rooijen, N., Goudsmit, J., Mcvey, J.H., Nicklin, S.A., and Baker, A.H. (2009) Effect of neutralizing sera on factor X-mediated adenovirus serotype 5 gene transfer. Journal of Virology, 83 (1). pp. 479-483. ISSN 0022-538X (doi:10.1128/JVI.01878-08)

Greig, J. et al. (2009) Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors. Molecular Therapy, 17 (10). pp. 1683-1691. ISSN 0006-4971 (doi:10.1038/mt.2009.152)

Greig, J.A. et al. (2009) Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors. Molecular Therapy, 17 (10). pp. 1683-1691. ISSN 1525-0016 (doi:10.1038/mt.2009.152)

Lenaerts, L, Mcvey, JH, Baker, AH, Denby, L, Nicklin, SA, Verbeken, E, and Naesens, L (2009) Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting. Journal of Gene Medicine, 11 (2). pp. 119-127. (doi:10.1002/jgm.1283)

Masson, R. et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension, 53 (4). pp. 694-700. ISSN 0194-911X (doi:10.1161/HYPERTENSIONAHA.108.122333)

2008

Parker, A.L., Nicklin, S.A., and Baker, A.H. (2008) Interactions of adenovirus vectors with blood: implications for intravascular gene therapy applications. Current Opinion in Molecular Therapeutics, 10 (5). pp. 439-448. ISSN 1464-8431

Graham, T, McIntosh, JB, Work, LM, Nathwani, A, and Baker, AH (2008) Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats. Genetic Vaccines and Therapy, 6 (1). p. 9. ISSN 1479-0556 (doi:10.1186/1479-0556-6-9)

White, K. et al. (2008) Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions. Gene Therapy, 15 (6). pp. 443-451. ISSN 0969-7128 (doi:10.1038/sj.gt.3303077)

Waddington, S. et al. (2008) Adenovirus serotype 5 hexon mediates liver gene transfer. Cell, 132 (3). pp. 397-409. ISSN 0092-8674 (doi:10.1016/j.cell.2008.01.016 )

Baker, AH (2008) Interaction of Ad5 with blood coagulation factor X mediates liver gene transfer. Human Gene Therapy, 19 (10). pp. 1072-1073. ISSN 1043-0342

Benest, A.V., Stone, O.A., Miller, W.H., Glover, C.P., Uney, J.B., Baker, A.H., Harper, S.J., and Bates, D.O. (2008) Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature. Arteriosclerosis, Thrombosis and Vascular Biology, 28 (8). pp. 1462-1468. ISSN 1079-5642 (doi:10.1161/ATVBAHA.108.169375 )

Buckley, SMK et al. (2008) Luciferin Detection After Intranasal Vector Delivery Is Improved by Intranasal Rather Than Intraperitoneal Luciferin Administration. Human Gene Therapy, 19 (10). pp. 1050-1056.

Flores-Munoz, M, Baker, AH, and Nicklin, SA (2008) Development of a gene transfer vector expressing angiotensin 1-7 and assessment of its effects on cardiac hypertrophy. Journal of Human Hypertension, 22 (10). p. 723. ISSN 0950-9240

Kane, N.M., McRae, S., Denning, C., and Baker, A.H. (2008) Viral and non-viral gene delivery and its role in pluripotent stem cell engineering. Drug Discovery Today: Technologies, 5 (4). e107-e115. (doi:10.1016/j.ddtec.2008.10.002)

Kritz Wilson, A.B., Yu, J., Wright, P.L., Wan, S., George, S.J., Halliday, C., Kang, N., Sessa, W.C., and Baker, A.H. (2008) In Vivo Modulation of Nogo-B Attenuates Neointima Formation. Molecular Therapy, 16 (11). pp. 1798-1804. ISSN 1525-0016 (doi:10.1038/mt.2008.188)

Miller, A.M., Xu, D., Asquith, D., Denby, L., Li, Y., Sattar, N., Baker, A.H., McInnes, I.B., and Liew, F.Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205 (2). pp. 339-346. ISSN 0022-1007 (doi:10.1084/jem.20071868 )

Nicklin, SA, and Baker, AH (2008) Efficient Vascular Endothelial Gene Transfer Following Intravenous Adenovirus Delivery. Molecular Therapy, 16 (12). pp. 1904-1905.

Parker, A, Parker, A, Mcvey, JH, Waddington, SN, Buckley, SMK, Francischetti, IMB, Monteiro, RQ, Nicklin, SA, and Baker, AH (2008) An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes. Human Gene Therapy, 19 (4). p. 34.

Wang, HJ et al. (2008) In Vitro and In Vivo Properties of Adenovirus Vectors with Increased Affinity to CD46. Journal of Virology, 82 (21). pp. 10567-10579. ISSN 0022-538X

2007

Waddington, S.N., Parker, A.L., Havenga, M., Nicklin, S.A., Buckley, S.M., McVey, J.H., and Baker, A.H. (2007) Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: Fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5. Journal of Virology, 81 (17). pp. 9568-9571. ISSN 0022-538X (doi:10.1128/JVI.00663-07)

Baker, AH, Mcvey, JH, Waddington, SN, Di Paolo, NC, and Shayakhmetov, DM (2007) The influence of blood on in vivo adenovirus bio-distribution and transduction. Molecular Therapy, 15 . pp. 1410-1416. (doi:10.1038/sj.mt.6300206)

Baker, AH, Nicklin, SA, and White, K (2007) Novel vectors for in vivo gene delivery to vascular tissue. Expert Opinion on Biological Therapy, 7 . pp. 809-821. (doi:10.1517/14712598.7.6.809)

Baker, AH et al. (2007) Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America, 104 . pp. 3597-3602. (doi:10.1073/pnas.0611112104)

Denby, L., Work, L.M., Von Seggern, D.J., Wu, E., Mcvey, J.H., Nicklin, S.A., and Baker, A.H. (2007) Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p. Molecular Therapy, 15 (9). pp. 1647-1654. ISSN 0006-4971 (doi:10.1038/sj.mt.6300214)

Kritz, AB, Nicol, CG, Dishart, KL, Nelson, R, Holbeck, S, Von Seggern, DJ, Work, LM, Mcvey, JH, Nicklin, SA, and Baker, AH (2007) Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop. Molecular Therapy, 15 . pp. 741-749. (doi:10.1038/sj.mt.6300094)

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115 (11). E326-E328.

Magnoni, S, Baker, A, Thomson, S, Jordan, G, George, SJ, Mccoll, BW, McCulloch, J, and Horsburgh, K (2007) Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and-2 in ischemic brain injury. Gene Therapy, 14 . pp. 621-625. (doi:10.1038/sj.gt.3302894)

Mccoll, BW, McGregor, AL, Wong, A, Harris, JD, Amalfitano, A, Magnoni, S, Baker, AH, Dickson, G, and Horsburgh, K (2007) APOE epsilon 3 gene transfer attenuates brain damage after experimental stroke. Journal of Cerebral Blood Flow and Metabolism, 27 . pp. 477-487. (doi:10.1038/sj.jcbfm.9600361)

Parker, AL, Mcvey, JH, Doctor, JH, Lopez-Franco, O, Waddington, SN, Havenga, MJE, Nicklin, SA, and Baker, AH (2007) Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D. Journal of Virology, 81 . pp. 3627-3631. ISSN 0022-538X (doi:10.1128/JVI.02786-06)

Sithu, SD, English, WR, Olson, P, Krubasik, D, Baker, AH, Murphy, G, and D'Souza, SE (2007) Membrane-type 1-matrix metalloproteinase regulates intracellular adhesion molecule-1 (ICAM-1)-mediated monocyte transmigration. Journal of Biological Chemistry, 282 . pp. 25010-25019. ISSN 0021-9258 (doi:10.1074/jbc.M611273200)

Smyth, A, Reid, HM, Baker, AH, and McGlynn, H (2007) Modifications of the radiosensitivity of a renal cancer cell line as a consequence of stable TIMP-1 overexpression. International Journal of Radiation Biology, 83 . pp. 13-25. (doi:10.1080/09553000600983136)

Toriseva, MJ, Ala-aho, R, Karvinen, J, Baker, AH, Marjomaki, VS, Heino, J, and Kahari, VM (2007) Collagenase-3 (MMP-13) enhances remodeling of three-dimensional collagen and promotes survival of human skin fibroblasts. Journal of Investigative Dermatology, 127 . pp. 49-59.

Van Roy, M, Wielockx, B, Baker, A, and Libert, C (2007) The use of tissue inhibitors of matrix metalloproteinases to increase the efficacy of a tumor necrosis factor/interferon gamma antitumor therapy. Cancer Gene Therapy, 14 . pp. 372-379. (doi:10.1038/sj.cgt.7701020)

Yoshida, S et al. (2007) Metalloproteinase inhibition has differential effects on alloimmunity, autoimmunity, and histopathology in the transplanted lung. Transplantation, 83 (6). pp. 799-808. ISSN 0041-1337 (doi:10.1097/01.tp.0000258600.05531.5d)

2006

Parker, A.L. et al. (2006) Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes in vitro and in vivo. Blood, 108 (8). pp. 2554-2561. ISSN 0006-4971 (doi:10.1182/blood-2006-04-008532 )

Baker, AH, Yim, APC, and Wan, S (2006) Opportunities for gene therapy in preventing vein graft failure after coronary artery bypass surgery. Diabetes Obesity and Metabolism, 8 . pp. 119-124. (doi:10.1111/j.1463-1326.2005.00494.x)

Finan, KM, Hodge, G, Reynolds, AM, Hodge, S, Holmes, MD, Baker, AH, and Reynolds, PN (2006) In vitro susceptibility to the pro-apoptotic effects of TIMP-3 gene delivery translates to greater in vivo efficacy versus gene delivery for TIMPs-1 or-2. Lung Cancer, 53 . pp. 273-284. (doi:10.1016/j.lungcan.2006.06.006)

George, SJ, Channon, KM, and Baker, AH (2006) Gene therapy and coronary artery bypass grafting: Current perspectives. Current Opinion in Molecular Therapeutics, 8 . pp. 288-294.

Heymans, S et al. (2006) Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis. Circulation, 114 . pp. 565-573. (doi:10.1161/CIRCULATIONAHA.105.591032)

Johnson, JL, Baker, AH, Oka, K, Chan, L, Newby, AC, Jackson, CL, and George, SJ (2006) Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2 - Involvement of macrophage migration and apoptosis. Circulation, 113 . pp. 2435-2444. (doi:10.1161/CIRCULATIONAHA.106.613281)

Kim, M, Bodenstine, TM, Sumerel, LA, Rivera, AA, Baker, AH, and Douglas, JT (2006) Tissue inhibitor of metalloproteinases-2 improves antitumor efficacy of a replicating adenovirus in vivo. Cancer Biology and Therapy, 5 . pp. 1647-1653.

Parker, AL et al. (2006) Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. Blood, 108 . pp. 2554-2561. (doi:10.1182/blood-2006-04-008532)

Perabo, L et al. (2006) Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism. Journal of Virology, 80 . pp. 7265-7269. ISSN 0022-538X (doi:10.1128/JVI.00076-06)

Work, L.M. et al. (2006) Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses. Molecular Therapy, 13 (4). pp. 683-693. (doi:10.1016/j.ymthe.2005.11.013)

de Nooijer, R., Verkleij, C.J.N., der Thusen, J.H., Jukema, J.W., van der Wall, E.E., van Berkel, T.J.C., Baker, A.H., and Biessen, E.A.L. (2006) Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis. Arteriosclerosis, Thrombosis and Vascular Biology, 26 . pp. 340-346. ISSN 1079-5642 (doi:10.1161/01.ATV.0000197795.56960.64)

2005

Akowuah, EF et al. (2005) Ultrasound-mediated delivery of TIMP-3 plasmid DNA into saphenous vein leads to increased lumen size in a porcine interposition graft model. Gene Therapy, 12 . pp. 1154-1157. (doi:10.1038/sj.gt.3302498)

Baker, AH, Kritz, A, Work, LM, Nicklin, SA, and Nicklin, A (2005) Cell-selective viral gene delivery vectors for the vasculature. Experimental Physiology, 90 . pp. 27-31. (doi:10.1113/expphysiol.2004.028126)

Baker, AH, Nemerow, GR, Nicklin, SA, and Wu, E (2005) The influence of adenovirus fiber structure and function on vector development for gene therapy. Molecular Therapy, 12 . pp. 384-393. (doi:10.1016/j.ymthe.2005.05.008)

Denby, L., Nicklin, S.A., and Baker, A.H. (2005) Adeno-associated virus (AAV)-7 and-8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation. Gene Therapy, 12 . pp. 1534-1538. ISSN 0969-7128 (doi:10.1038/sj.gt.3302564)

Heymans, S, Lupu, F, Terclavers, S, Vanwetswinkel, B, Herbert, JM, Baker, A, Collen, D, Carmeliet, P, and Moons, L (2005) Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice. American Journal of Pathology, 166 (1). pp. 15-25. ISSN 0002-9440

Lovelock, J.D., Baker, A.H., Gao, F., Dong, J.F., Bergeron, A.L., McPheat, W., Sivasubramanian, N., and Mann, D.L. (2005) Heterogeneous effects of tissue inhibitors of matrix metalloproteinases on cardiac fibroblasts. American Journal of Physiology: Heart and Circulatory Physiology, 288 . H461-H468. ISSN 0363-6135 (doi:10.1152/ajpheart.00402.2004)

Miller, W.H., Nicklin, S.A., Baker, A.H., and Dominiczak, A. (2005) Gene transfer and the cardiovascular system. In: Raizada, M.K., Paton, J.F.R., Kasparov, S. and Katovich, M.J. (eds.) Cardiovascular Genomics. Series: Contemporary cardiology . Humana Press, Totowa, NJ, USA, pp. 175-196. ISBN 9781588294005

Miller, WH, Brosnan, MJ, Graham, D, Nicol, CG, Morecroft, I, Channon, KM, Danilov, SM, Reynolds, PN, Baker, AH, and Dominiczak, AF (2005) Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats. Molecular Therapy, 12 . pp. 321-327. (doi:10.1016/j.ymthe.2005.02.025)

Parker, AL, Fisher, KD, Oupicky, D, Read, ML, Nicklin, SA, Baker, AH, and Seymour, LW (2005) Enhanced gene transfer activity of peptide-targeted gene-delivery vectors. Journal of Drug Targeting, 13 . pp. 39-51. (doi:10.1080/10611860400020449)

White, SJ, Simmonds, RE, Lane, DA, and Baker, AH (2005) Efficient isolation of peptide ligands for the endothelial cell protein C receptor (EPCR) using candidate receptor phage display biopanning. Peptides, 26 . pp. 1264-1269. (doi:10.1016/j.peptides.2005.01.015)

2004

Baker, AH (2004) Designing gene delivery vectors for cardiovascular gene therapy. Progress in Biophysics and Molecular Biology, 84 . pp. 279-299. (doi:10.1016/j.pbiomolbio.2003.11.006)

Denby, L., Work, L.M., Graham, D., Hsu, C., Von Seggern, D.J., Nicklin, S.A., and Baker, A.H. (2004) Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. Human Gene Therapy, 15 (11). pp. 1054-1064. ISSN 1043-0342

Elezkurtaj, S, Kopitz, C, Baker, AH, Perez-Canto, A, Arlt, MJE, Khokha, R, Gansbacher, B, Anton, M, Brand, K, and Kruger, A (2004) Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis. Journal of Gene Medicine, 6 . pp. 1228-1237. (doi:10.1002/jgm.637)

Magnoni, S, Baker, A, George, SJ, Duncan, WC, Kerr, LE, McCulloch, J, and Horsburgh, K (2004) Differential alterations in the expression and activity of matrix metalloproteinases 2 and 9 after transient cerebral ischemia in mice. Neurobiology of Disease, 17 . pp. 188-197. (doi:10.1016/j.nbd.2004.07.020)

Nicklin, SA, White, SJ, Nicol, CG, Von Seggern, DJ, and Baker, AH (2004) In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors. Journal of Gene Medicine, 6 . pp. 300-308. (doi:10.1002/jgm.526)

Nicol, CG, Graham, D, Miller, WH, White, SJ, Smith, TAG, Nicklin, SA, Stevenson, SC, and Baker, AH (2004) Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats. Molecular Therapy, 10 . pp. 344-354. (doi:10.1016/j.ymthe.2004.05.020)

Papadakis, ED, Nicklin, SA, Baker, AH, and White, SJ (2004) Promoters and control elements: Designing expression cassettes for gene therapy. Current Gene Therapy, 4 . pp. 89-113.

Wan, S, George, SJ, Nicklin, SA, Yim, APC, and Baker, AH (2004) Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein grafts. Molecular Therapy, 9 . pp. 689-698. (doi:10.1016/j.ymthe.2004.02.005)

White, SJ, Nicklin, SA, Buning, H, Brosnan, MJ, Leike, K, Papadakis, ED, Hallek, M, and Baker, AH (2004) Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors. Circulation, 109 . pp. 513-519. (doi:10.1161/01.CIR.0000109697.68832.5D)

Work, L.M., Nicol, C.G., Denby, L., and Baker, A.H. (2004) In vivo biopanning: a methodological approach to identifying novel targeting ligands for delivery of biological agents to the vasculature. In: Fennell, J.P. and Baker, A.H. (eds.) Hypertension: Methods and Protocols. Series: Methods in molecular medicine (108). Humana Press, Totowa, NJ, USA, pp. 395-413. ISBN 9781588293237

Work, LM, Nicklin, SA, Brain, NJR, Dishart, KL, Von Seggern, DJ, Hallek, M, Buning, H, and Baker, AH (2004) Development of efficient viral vectors selective for vascular smooth muscle cells. Molecular Therapy, 9 . pp. 198-208. (doi:10.1016/j.ymthe.2003.11.006)

Work, LM, Reynolds, P, and Baker, A (2004) Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector. Genetic Vaccines and Therapy, 2 (1). p. 14. (doi:10.1186/1479-0556-2-14)

Work, LM, Ritchie, N, Nicklin, SA, Reynolds, PN, and Baker, AH (2004) Dual targeting of gene delivery by genetic modification of adenovirus serotype 5 fibers and cell-selective transcriptional control. Gene Therapy, 11 . pp. 1296-1300. (doi:10.1038/sj.gt.3302292)

2003

Ahonen, M, Poukkula, M, Baker, AH, Kashiwagi, M, Nagase, H, Eriksson, JE, and Kahari, VM (2003) Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors. Oncogene, 22 . pp. 2121-2134. (doi:10.1038/sj.onc.1206292)

Baker, AH (2003) Targeting AAV vectors. Molecular Therapy, 7 (4). pp. 433-434.

Baker, AH, Denby, L, Dishart, KL, and Work, LM (2003) Gene therapy for cardiovascular disease. Journal of Biomedicine and Biotechnology . pp. 138-148.

Buning, H, Nicklin, SA, Perabo, L, Hallek, M, and Baker, AH (2003) AAV-based gene transfer. Current Opinion in Molecular Therapeutics, 5 . pp. 367-375.

Dishart, K.L. et al. (2003) Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy. Journal of Molecular and Cellular Cardiology, 35 (7). pp. 739-748. ISSN 0022-2828 (doi:10.1016/S0022-2828(03)00136-6)

Gruss, CJ et al. (2003) Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. Journal of Investigative Dermatology, 120 . pp. 683-692.

Lambert, V et al. (2003) MMP-2 and MMP-9 synergize in promoting choroidal neovascularization. FASEB Journal, 17 (13). 2290-+.

MacKenzie, CJ, Paul, A, Wilson, S, de Martin, R, Baker, AH, and Plevin, R (2003) Enhancement of lipopolysaccharide-stimulated JNK activity in rat aortic smooth muscle cells by pharmacological and adenovirusmediated inhibition of inhibitory kappa B kinase signalling. British Journal of Pharmacology, 139 . pp. 1041-1049. (doi:10.1038/sj.bjp.0705330)

Nicklin, S.A., and Baker, A.H. (2003) Development of targeted viral vectors for cardiovascular gene therapy. In: Setlow, J.K. (ed.) Genetic Engineering, Principles and Methods. Kluwer Academic, Dordrecht, The Netherlands, pp. 15-49. ISBN 9780306477768

Nicklin, SA, Dishart, KL, Buening, H, Reynolds, PN, Hallek, M, Nemerow, GR, Von Seggern, DJ, and Baker, AH (2003) Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors. Cancer Letters, 201 . pp. 165-173. (doi:10.1016/j.canlet.2003.07.003)

Qi, JH, Ebrahem, Q, Moore, N, Murphy, G, Claesson-Welsh, L, Bond, M, Baker, A, and Anand-Apte, B (2003) A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nature Medicine, 9 . pp. 407-415. (doi:10.1038/nm846)

Tan, HK, Heywood, D, Ralph, GS, Bienemann, A, Baker, AH, and Uney, JB (2003) Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons. Molecular and Cellular Neuroscience, 22 . pp. 98-106. (doi:10.1016/S1044-7431(02)00024-6)

Vieillard-Baron, A, Frisdal, E, Raffestin, B, Baker, AH, Eddahibi, S, Adnot, S, and D'Ortho, MP (2003) Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats. Human Gene Therapy, 14 . pp. 861-869.

Work, LM, Nicklin, SA, and Baker, AH (2003) Targeting Gene Therapy Vectors to the Vascular Endothelium. Current Atherosclerosis Reports, 5 (3). pp. 163-170.

de Nigris, F, Lerman, A, Ignarro, LJ, Williams-Ignarro, S, Sica, V, Baker, AH, Lerman, LO, Geng, YJ, and Napoli, C (2003) Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis. Trends in Molecular Medicine, 9 . pp. 351-359. (doi:10.1016/S1471-4914(03)00139-4)

2002

Ahonen, M, Ala-aho, R, Baker, AH, George, SJ, Grenman, R, Saarialho-Kere, U, and Kahari, VM (2002) Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3. Molecular Therapy, 5 . pp. 705-715. (doi:10.1106/mthe.2002.0606)

Ala-aho, R, Johansson, N, Baker, AH, and Kahari, VM (2002) Expression of collagenase-3 (MMP-13) enhances invasion of human fibrosarcoma HT-1080 cells. International Journal of Cancer, 97 . pp. 283-289. (doi:10.1002/ijc.1619)

Bainbridge, JWB, Mistry, A, De Alwis, M, Paleolog, E, Baker, A, Thrasher, AJ, and Ali, RR (2002) Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Therapy, 9 . pp. 320-326. (doi:10.1038/sj/gt/3301680)

Baker, AH (2002) Development and use of gene transfer for treatment of cardiovascular disease. Journal of Cardiac Surgery, 17 . pp. 543-548.

Baker, AH (2002) Gene therapy for bypass graft failure and restenosis. Pathophysiology of Haemostasis and Thrombosis, 32 . pp. 389-391.

Baker, AH, Edwards, DR, and Murphy, G (2002) Metalloproteinase inhibitors: biological actions and therapeutic opportunities. Journal of Cell Science, 115 . pp. 3719-3727. (doi:10.1242/jcs.00063)

Baker, AH, Nicklin, SA, White, SJ, and Work, LM (2002) Use of phage display to identify novel peptides for targeted gene therapy. Gene Therapy Methods, 346 . pp. 157-176.

Bauerschmitz, GJ, Nettelbeck, DM, Kanerva, A, Baker, AH, Hemminki, A, Reynolds, PN, and Curiel, DT (2002) The flt-1 promoter for transcriptional targeting of teratocarcinoma. Cancer Research, 62 . pp. 1271-1274.

Bond, M, Murphy, G, Bennett, MR, Newby, AC, and Baker, AH (2002) Tissue inhibitor of metalloproteinase-3 induces a Fas-associated death domain-dependent type II apoptotic pathway. Journal of Biological Chemistry, 277 . pp. 13787-13795. ISSN 0021-9258 (doi:10.1074/jbc.M111507200)

Fennell, JP, Brosnan, MJ, Frater, AJ, Hamilton, CA, Alexander, MY, Nicklin, SA, Heistad, DD, Baker, AH, and Dominiczak, AF (2002) Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension. Gene Therapy, 9 . pp. 110-117. (doi:10.1038/sj/gt/3301633)

Majid, MA, Smith, VA, Easty, DL, Baker, AH, and Newby, AC (2002) Adenovirus mediated gene delivery of tissue inhibitor of metalloproteinases-3 induces death in retinal pigment epithelial cells. British Journal of Ophthalmology, 86 (1). pp. 97-101.

Majid, MA, Smith, VA, Easty, DL, Baker, AH, and Newby, AC (2002) Sorsby's fundus dystrophy mutant tissue inhibitors of metalloproteinase-3 induce apoptosis of retinal pigment epithelial and MCF-7 cells. Febs Letters, 529 . pp. 281-285.

Nicklin, SA, and Baker, AH (2002) Tropism-Modified Adenoviral and Adeno-Associated Viral Vectors for Gene Therapy. Current Gene Therapy, 2 (3). pp. 273-293.

Turunen, MP et al. (2002) Peptide-retargeted adenovirus encoding a tissue inhibitor of metalloproteinase-1 decreases restenosis after intravascular gene transfer. Molecular Therapy, 6 . pp. 306-312. (doi:10.1006/mthe.2002.0668)

Van de Louw, A, Jean, D, Frisdal, E, Cerf, C, D'Ortho, MP, Baker, AH, Lafuma, C, Duvaldestin, P, Harf, A, and Delclaux, C (2002) Neutrophil proteinases in hydrochloric acid- and endotoxin-induced acute lung injury: Evaluation of interstitial protease activity by in situ zymography. Laboratory Investigation, 82 . pp. 133-145.

2001

Apparailly, F, Noel, D, Millet, V, Baker, AH, Lisignoli, G, Jacquet, C, Kaiser, MJ, Sany, J, and Jorgensen, C (2001) Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis. Arthritis and Rheumatism, 44 . pp. 1444-1454. ISSN 0004-3591

Bond, M, Chase, AJ, Baker, AH, and Newby, AC (2001) Inhibition of transcription factor NF-kappa B reduces matrix metalloproteinase-1,-3 and-9 production by vascular smooth muscle cells. Cardiovascular Research, 50 . pp. 556-565.

George, SJ, Angelini, GD, Capogrossi, MC, and Baker, AH (2001) Wild-type p53 gene transfer inhibits neointima formation in human saphenous vein by modulation of smooth muscle cell migration and induction of apoptosis. Gene Therapy, 8 (9). pp. 668-676.

Hu, Y.H., Baker, A.H., Zou, Y.P., Newby, A.C., and Xu, Q.B. (2001) Local gene transfer of tissue inhibitor of metalloproteinase-2 influences vein graft remodeling in a mouse model. Arteriosclerosis, Thrombosis and Vascular Biology, 21 (8). pp. 1275-1280. ISSN 1079-5642

Nicklin, SA, Buening, H, Dishart, KL, De Alwis, M, Girod, A, Hacker, U, Thrasher, AJ, Ali, RR, Hallek, M, and Baker, AH (2001) Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells. Molecular Therapy, 4 . pp. 174-181.

Nicklin, SA, Reynolds, PN, Brosnan, MJ, White, SJ, Curiel, DT, Dominiczak, AF, and Baker, AH (2001) Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endothelium. Hypertension, 38 . pp. 65-70.

Nicklin, SA, Von Seggern, DJ, Work, LM, Pek, DC, Dominiczak, AF, Nemerow, GR, and Baker, AH (2001) Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus. Molecular Therapy, 4 . pp. 534-542. (doi:10.1006/mthe.2001.0489)

Reynolds, PN, Nicklin, SA, Kaliberova, L, Boatman, BG, Grizzle, WE, Balyasnikova, IV, Baker, AH, Danilov, SM, and Curiel, DT (2001) Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo. Nature Biotechnology, 19 . pp. 838-842.

White, SJ, Nicklin, SA, Sawamura, T, and Baker, AH (2001) Identification of peptides that target the endothelial cell-specific LOX-1 receptor. Hypertension, 37 . pp. 449-455.

2000

Amour, A, Baker, AH, Bennett, MR, Bond, M, Knauper, V, Murphy, G, and Newby, AC (2000) Localization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus - Metalloproteinase inhibition is associated with proapoptotic activity. Journal of Biological Chemistry, 275 (52). pp. 41358-41363. ISSN 0021-9258