Diabetes, Renal, Endocrine & Metabolic Disease (DREAM)

Our Theme 

This theme is currently led by Prof John Petrie (Diabetic Medicine) and Prof Naveed Sattar (Metabolic Medicine) with Dr Jason Gill providing leadership in the field of exercise and metabolism. 

As a group of established Principal Investigators and emerging young researchers, we encourage and foster collaborations within the Institute of Cardiovascular and Medical Sciences, within the University of Glasgow,  nationally and internationally. 

Our Aims

(i) better understand the mechanisms of cardiovascular and metabolic diseases affecting people with the conditions covered by our clinical specialties (i.e. diabetes, renal disease, endocrine conditions), and the implications for the wider population - including groups defined by ethnicity, gender and deprivation;

(ii) understand the pathways and processes linking obesity and physical inactivity to cardiovascular and metabolic diseases in order to develop better strategies to prevent and treat obesity, and alleviate its metabolic and vascular complications; 

(iii) use this knowledge both to develop new cardiovascular therapies and target existing ones more effectively.

Our Expertise

The collective expertise within the DREAM theme spans a full range from molecular and biomarker/ “-omic” techniques through clinical investigation to population-level epidemiology, clinical trials and cardiovascular endpoint adjudication.  We are leading in establishing disease-specific bioresources linked with routinely-acquired anonymised data from the National Health Service in Scotland.

Our Research

Particular areas of interest include regulation of carbohydrate and lipid metabolism, novel biomarkers, steroid action and the mechanisms underlying vascular disease associated with metabolic disorders.