Dr Liane Mcglynn

  • Research Associate (Clinical Trials Research)

telephone: 01413306686
email: Liane.McGlynn@glasgow.ac.uk

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Endocytic Trafficking and Response to Therapy in HER2+ve Breast Cancer
    NHS Endowment Funds
    2014 - 2015
     
  • The role of telomere dynamics and epigenetic status in breast cancer
    NHS Greater Glasgow & Clyde West Research Endowment Fund
    2010 - 2010
     

Publications

List by: Type | Date

Jump to: 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005
Number of items: 28.

2014

McGlynn, L.M. et al. (2014) SIRT2: Tumour suppressor or tumour promoter in operable breast cancer? European Journal of Cancer, 50(2), pp. 290-301. (doi:10.1016/j.ejca.2013.10.005) (PMID:24183459)

2013

Rutherford, C. et al. (2013) Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1. Cell Death and Disease, 4(11), e927. (doi:10.1038/cddis.2013.455)

McGlynn, L.M., Tovey, S., Bartlett, J.M.S., Doughty, J., Cooke, T.G., and Edwards, J. (2013) Interactions between MAP kinase and oestrogen receptor in human breast cancer. European Journal of Cancer, 49(6), pp. 1176-1186. (doi:10.1016/j.ejca.2012.11.020)

McGlynn, L.M., Eller, K., MacDonald, A.I., MacIntyre, A., Russell, D., Koppelstaetter, C., Davies, R., and Shiels, P.G. (2013) Pathfinder cells provide a novel therapeutic intervention for acute kidney injury. Rejuvenation Research, 16(1), pp. 11-20. (doi:10.1089/rej.2012.1350)

Gingell-Littlejohn, M., McGuinness, D., McGlynn, L.M., Kingsmore, D., Stevenson, K.S., Koppelstaetter, C., Clancy, M.J., and Shiels, P. (2013) Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria. PLoS ONE, 8(7), e68133. (doi:10.1371/journal.pone.0068133)

Pathai, S. et al. (2013) Accelerated biological aging in HIV-infected individuals in South Africa: a case–control study. AIDS, 27(15), pp. 2375-2384. (doi:10.1097/QAD.0b013e328363bf7f)

Roxburgh, C.S., Richards, C.H., MacDonald, A.I., Powell, A.G., McGlynn, L.M., McMillan, D.C., Horgan, P.G., Edwards, J., and Shiels, P.G. (2013) The in situ local immune response, tumour senescence and proliferation in colorectal cancer. British Journal of Cancer, 109(8), pp. 2207-2216. (doi:10.1038/bjc.2013.556)

2012

Sebastián, C. et al. (2012) The histone deacetylase SIRT6 is a novel tumor suppressor that controls cancer metabolism. Cell, 151(6), pp. 1185-1199. (doi:10.1016/j.cell.2012.10.047)

Sebastián, C. et al. (2012) The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell, 151(6), pp. 1185-1199. (doi:10.1016/j.cell.2012.10.047)

Robertson, T., Batty, G.D., Der, G., Green, M.J., McGlynn, L.M., McIntyre, A., Shiels, P.G., and Benzeval, M. (2012) Is telomere length socially patterned? Evidence from the West of Scotland Twenty-07 study. PLoS ONE, 7(7), e41805. (doi:10.1371/journal.pone.0041805)

McGuinness, D. et al. (2012) Socio-economic status is associated with epigenetic differences in the pSoBid cohort. International Journal of Epidemiology, 41(1), pp. 151-160. (doi:10.1093/ije/dyr215)

Der, G., Batty, G.D., Benzeval, M., Deary, I.J., Green, M.J., McGlynn, L., McIntyre, A., Robertson, T., and Shiels, P.G. (2012) Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland? PLoS ONE, 7(9), e45166. (doi:10.1371/journal.pone.0045166)

Gardani, M., McMillan, T., Shiels, P., McGlynn, L., and Stewart, E. (2012) An investigation of biological ageing processes following head injury. In: International Brain Injury Association's Ninth World Congress on Brain Injury, Edinburgh, UK, 21-25 Mar 2012, pp. 309-799. (doi:10.3109/02699052.2012.660091)

2011

Maxwell, F., McGlynn, L.M., Muir, H.C., Talwar, D., Benzeval, M., Robertson, T., Roxburgh, C.S., McMillan, D., Horgan, P.G., and Shiels, P. (2011) Telomere attrition and decreased Fetuin A levels indicate accelerated biological ageing and are implicated in the pathogenesis of colorectal cancer. Clinical Cancer Research, 17(17), pp. 5573-5581. (doi:10.1158/1078-0432.CCR-10-3271)

Shiels, P.G. et al. (2011) Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort. PLoS ONE, 6(7), e22521. (doi:10.1371/journal.pone.0022521)

Stevenson, K. et al. (2011) Pancreatic derived pathfinder cells enable regeneration of critically damaged adult pancreatic tissue and completely reverse streptozotocin induced diabetes. Rejuvenation Research, 14(2), pp. 163-171. (doi:10.1089/rej.2010.1099)

2010

Watson, C., Long, J.S., Orange, C., Tannahill, C.L., Mallon, E., McGlynn, L.M., Pyne, S., Pyne, N.J., and Edwards, J. (2010) High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients. American Journal of Pathology, 177(5), pp. 2205-2215. (doi:10.2353/ajpath.2010.100220)

2009

Stevenson, K.S., McGlynn, L.M., Hodge, M., McLinden, H., George, W.D., Davies, R.W., and Shiels, P.G. (2009) Isolation, characterization, and differentiation of Thy1.1-sorted pancreatic adult progenitor cell populations. Stem Cells and Development, 18(10), pp. 1389-1398. (doi:10.1089/scd.2008.0301)

Stevenson, K.S., McGlynn, L.M., and Shiels, P.G. (2009) Stem cells: outstanding potential and outstanding questions. Scottish Medical Journal, 54(4), pp. 35-37. (doi:10.1258/rsmsmj.54.4.35 )

McGlynn, L.M., Kirkegaard, T., Edwards, J., Tovey, S., Cameron, D., Twelves, C., Bartlett, J.M.S., and Cooke, T.G. (2009) Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients. Clinical Cancer Research, 15(4), pp. 1487-1495. (doi:10.1158/1078-0432.CCR-07-4967)

McGlynn, L.M., Stevenson, K., Lamb, K., Zino, S., Brown, M., Prina, A., Kingsmore, D., and Shiels, P.G. (2009) Cellular senescence in pre-transplant renal biopsies predicts postoperative organ function. Aging Cell, 8(1), pp. 45-51. (doi:10.1111/j.1474-9726.2008.00447.x)

Brown, S.B.F., Mallon, E.A., Edwards, J., Campbell, F.M., McGlynn, L.M., Elsberger, B., and Cooke, T.G. (2009) Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997. British Journal of Cancer, 100(5), pp. 807-810. (doi:10.1038/sj.bjc.6604934)

2008

Maclntyre, A., Brouilette, S.W., Lamb, K., Radhakrishnan, K., McGlynn, L.M., Chee, M.M., Parkinson, E.K., Freeman, D., Madhok, R., and Shiels, P.G. (2008) Association of increased telomere lengths in limited scleroderma, with a lack of age-related telomere erosion. Annals of the Rheumatic Diseases, 67(12), pp. 1780-1782. (doi:10.1136/ard.2007.086652)

Traynor, P., McGlynn, L.M., Mukherjee, R., Grimsley, S.L.S., Bartlett, J.M.S., and Edwards, J. (2008) An increase in N-Ras expression is associated with development of hormone refractory prostate cancer in a subset of patients. Disease Markers, 24(3), pp. 157-165.

2007

Kirkegaard, T., McGlynn, L.M., Campbell, F.M., Muller, S., Tovey, S.M., Dunne, B., Nielsen, K.V., Cooke, T.G., and Bartlett, J.M. (2007) Amplified in breast cancer 1 in human epidermal growth factor receptor - positive tumors of tamoxifen-treated breast cancer patients. Clinical Cancer Research, 13(5), pp. 1405-1411. (doi:10.1158/1078-0432.CCR-06-1933)

Tam, L., McGlynn, L.M., Traynor, P., Mukherjee, R., Bartlett, J.M.S., and Edwards, J. (2007) Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. British Journal of Cancer, 97(3), pp. 378-383. (doi:10.1038/sj.bjc.6603871)

2006

Kirkegaard, T., Edwards, J., Tovey, S., McGlynn, L.M., Krishna, S.N., Mukherjee, R., Tam, L., Munro, A.F., Dunne, B., and Bartlett, J.M. (2006) Observer variation in immunohistochemical analysis of protein expression, time for a change? Histopathology, 48(7), pp. 787-794. (doi:10.1111/j.1365-2559.2006.02412.x)

2005

Kirkegaard, T., Witton, C.J., McGlynn, L.M., Tovey, S.M., Dunne, B., Lyon , A., and Bartlett, J.M. (2005) AKT activation predicts outcome in breast cancer patients treated with tamoxifen. Journal of Pathology, 207(2), pp. 139-146. (doi:10.1002/path.1829)

This list was generated on Sat Jul 4 06:02:12 2015 BST.
Number of items: 28.

Articles

McGlynn, L.M. et al. (2014) SIRT2: Tumour suppressor or tumour promoter in operable breast cancer? European Journal of Cancer, 50(2), pp. 290-301. (doi:10.1016/j.ejca.2013.10.005) (PMID:24183459)

Rutherford, C. et al. (2013) Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1. Cell Death and Disease, 4(11), e927. (doi:10.1038/cddis.2013.455)

McGlynn, L.M., Tovey, S., Bartlett, J.M.S., Doughty, J., Cooke, T.G., and Edwards, J. (2013) Interactions between MAP kinase and oestrogen receptor in human breast cancer. European Journal of Cancer, 49(6), pp. 1176-1186. (doi:10.1016/j.ejca.2012.11.020)

McGlynn, L.M., Eller, K., MacDonald, A.I., MacIntyre, A., Russell, D., Koppelstaetter, C., Davies, R., and Shiels, P.G. (2013) Pathfinder cells provide a novel therapeutic intervention for acute kidney injury. Rejuvenation Research, 16(1), pp. 11-20. (doi:10.1089/rej.2012.1350)

Gingell-Littlejohn, M., McGuinness, D., McGlynn, L.M., Kingsmore, D., Stevenson, K.S., Koppelstaetter, C., Clancy, M.J., and Shiels, P. (2013) Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria. PLoS ONE, 8(7), e68133. (doi:10.1371/journal.pone.0068133)

Pathai, S. et al. (2013) Accelerated biological aging in HIV-infected individuals in South Africa: a case–control study. AIDS, 27(15), pp. 2375-2384. (doi:10.1097/QAD.0b013e328363bf7f)

Roxburgh, C.S., Richards, C.H., MacDonald, A.I., Powell, A.G., McGlynn, L.M., McMillan, D.C., Horgan, P.G., Edwards, J., and Shiels, P.G. (2013) The in situ local immune response, tumour senescence and proliferation in colorectal cancer. British Journal of Cancer, 109(8), pp. 2207-2216. (doi:10.1038/bjc.2013.556)

Sebastián, C. et al. (2012) The histone deacetylase SIRT6 is a novel tumor suppressor that controls cancer metabolism. Cell, 151(6), pp. 1185-1199. (doi:10.1016/j.cell.2012.10.047)

Sebastián, C. et al. (2012) The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell, 151(6), pp. 1185-1199. (doi:10.1016/j.cell.2012.10.047)

Robertson, T., Batty, G.D., Der, G., Green, M.J., McGlynn, L.M., McIntyre, A., Shiels, P.G., and Benzeval, M. (2012) Is telomere length socially patterned? Evidence from the West of Scotland Twenty-07 study. PLoS ONE, 7(7), e41805. (doi:10.1371/journal.pone.0041805)

McGuinness, D. et al. (2012) Socio-economic status is associated with epigenetic differences in the pSoBid cohort. International Journal of Epidemiology, 41(1), pp. 151-160. (doi:10.1093/ije/dyr215)

Der, G., Batty, G.D., Benzeval, M., Deary, I.J., Green, M.J., McGlynn, L., McIntyre, A., Robertson, T., and Shiels, P.G. (2012) Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland? PLoS ONE, 7(9), e45166. (doi:10.1371/journal.pone.0045166)

Maxwell, F., McGlynn, L.M., Muir, H.C., Talwar, D., Benzeval, M., Robertson, T., Roxburgh, C.S., McMillan, D., Horgan, P.G., and Shiels, P. (2011) Telomere attrition and decreased Fetuin A levels indicate accelerated biological ageing and are implicated in the pathogenesis of colorectal cancer. Clinical Cancer Research, 17(17), pp. 5573-5581. (doi:10.1158/1078-0432.CCR-10-3271)

Shiels, P.G. et al. (2011) Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort. PLoS ONE, 6(7), e22521. (doi:10.1371/journal.pone.0022521)

Stevenson, K. et al. (2011) Pancreatic derived pathfinder cells enable regeneration of critically damaged adult pancreatic tissue and completely reverse streptozotocin induced diabetes. Rejuvenation Research, 14(2), pp. 163-171. (doi:10.1089/rej.2010.1099)

Watson, C., Long, J.S., Orange, C., Tannahill, C.L., Mallon, E., McGlynn, L.M., Pyne, S., Pyne, N.J., and Edwards, J. (2010) High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients. American Journal of Pathology, 177(5), pp. 2205-2215. (doi:10.2353/ajpath.2010.100220)

Stevenson, K.S., McGlynn, L.M., Hodge, M., McLinden, H., George, W.D., Davies, R.W., and Shiels, P.G. (2009) Isolation, characterization, and differentiation of Thy1.1-sorted pancreatic adult progenitor cell populations. Stem Cells and Development, 18(10), pp. 1389-1398. (doi:10.1089/scd.2008.0301)

Stevenson, K.S., McGlynn, L.M., and Shiels, P.G. (2009) Stem cells: outstanding potential and outstanding questions. Scottish Medical Journal, 54(4), pp. 35-37. (doi:10.1258/rsmsmj.54.4.35 )

McGlynn, L.M., Kirkegaard, T., Edwards, J., Tovey, S., Cameron, D., Twelves, C., Bartlett, J.M.S., and Cooke, T.G. (2009) Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients. Clinical Cancer Research, 15(4), pp. 1487-1495. (doi:10.1158/1078-0432.CCR-07-4967)

McGlynn, L.M., Stevenson, K., Lamb, K., Zino, S., Brown, M., Prina, A., Kingsmore, D., and Shiels, P.G. (2009) Cellular senescence in pre-transplant renal biopsies predicts postoperative organ function. Aging Cell, 8(1), pp. 45-51. (doi:10.1111/j.1474-9726.2008.00447.x)

Brown, S.B.F., Mallon, E.A., Edwards, J., Campbell, F.M., McGlynn, L.M., Elsberger, B., and Cooke, T.G. (2009) Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997. British Journal of Cancer, 100(5), pp. 807-810. (doi:10.1038/sj.bjc.6604934)

Maclntyre, A., Brouilette, S.W., Lamb, K., Radhakrishnan, K., McGlynn, L.M., Chee, M.M., Parkinson, E.K., Freeman, D., Madhok, R., and Shiels, P.G. (2008) Association of increased telomere lengths in limited scleroderma, with a lack of age-related telomere erosion. Annals of the Rheumatic Diseases, 67(12), pp. 1780-1782. (doi:10.1136/ard.2007.086652)

Traynor, P., McGlynn, L.M., Mukherjee, R., Grimsley, S.L.S., Bartlett, J.M.S., and Edwards, J. (2008) An increase in N-Ras expression is associated with development of hormone refractory prostate cancer in a subset of patients. Disease Markers, 24(3), pp. 157-165.

Kirkegaard, T., McGlynn, L.M., Campbell, F.M., Muller, S., Tovey, S.M., Dunne, B., Nielsen, K.V., Cooke, T.G., and Bartlett, J.M. (2007) Amplified in breast cancer 1 in human epidermal growth factor receptor - positive tumors of tamoxifen-treated breast cancer patients. Clinical Cancer Research, 13(5), pp. 1405-1411. (doi:10.1158/1078-0432.CCR-06-1933)

Tam, L., McGlynn, L.M., Traynor, P., Mukherjee, R., Bartlett, J.M.S., and Edwards, J. (2007) Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer. British Journal of Cancer, 97(3), pp. 378-383. (doi:10.1038/sj.bjc.6603871)

Kirkegaard, T., Edwards, J., Tovey, S., McGlynn, L.M., Krishna, S.N., Mukherjee, R., Tam, L., Munro, A.F., Dunne, B., and Bartlett, J.M. (2006) Observer variation in immunohistochemical analysis of protein expression, time for a change? Histopathology, 48(7), pp. 787-794. (doi:10.1111/j.1365-2559.2006.02412.x)

Kirkegaard, T., Witton, C.J., McGlynn, L.M., Tovey, S.M., Dunne, B., Lyon , A., and Bartlett, J.M. (2005) AKT activation predicts outcome in breast cancer patients treated with tamoxifen. Journal of Pathology, 207(2), pp. 139-146. (doi:10.1002/path.1829)

Conference Proceedings

Gardani, M., McMillan, T., Shiels, P., McGlynn, L., and Stewart, E. (2012) An investigation of biological ageing processes following head injury. In: International Brain Injury Association's Ninth World Congress on Brain Injury, Edinburgh, UK, 21-25 Mar 2012, pp. 309-799. (doi:10.3109/02699052.2012.660091)

This list was generated on Sat Jul 4 06:02:12 2015 BST.