Professor Gwyn Gould

  • Professor of Cell Biology (Institute of Molecular Cell and Systems Biology)

telephone: 01413305263
email: Gwyn.Gould@glasgow.ac.uk

Research interests

The role of membrane traffic in cytokinesis. SNARE protein function and regulation. Regulated membrane traffic in adipocytes.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Control of GLUT4 sorting by Syntaxin 16 and mVps45 in adipocytes
    Diabetes UK
    2014 - 2016
     
  • Commonwealth Fellowship
    Commonwealth Scholarship Commission in the UK
    2012 - 2012
     
  • How does tyrosine phosphorylation of SNARE proteins control GLUT4 vesicle fusion with the plasma membrane?
    Diabetes UK
    2012 - 2015
     
  • Role of ubiquitination as a transient modification in regulated protein trafficking
    Medical Research Council
    2012 - 2015
     
  • The sensitive assessment of the activity of cellular signalling pathways regulating insulin action and the cardiovascular complications of diabetes
    Diabetes UK
    2011 - 2014
     
  • Investigation of the role of Syntaxin 16 and mVps45 in cytokinesis
    Cancer Research UK
    2011 - 2014
     
  • How does Syntaxin 16 control Glut4 sorting?
    Diabetes Research & Wellness Foundation
    2011 - 2012
     
  • How does mVps45 regulate Glut4 sorting in adipocytes
    Diabetes UK
    2010 - 2012
     
  • Phosphoryaltion of FIP3 and its consequence for cytokinesis
    Cancer Research UK
    2009 - 2012
     
  • Regulation and role of the Exocyst complex in cytokinesis.
    Cancer Research UK
    2009 - 2011
     
  • Tyrosine phosphorylation of Munc18c in insulin action
    Diabetes Research & Wellness Foundation
    2009 - 2009
     
  • Translational analysis of the role of synaptotagmins in the adipocyte, and their relationship to insulin action
    Scottish Executive Health Department
    2008 - 2010
     
  • The role of mvps45 in Glut4 trafficking in adipocytes
    Diabetes UK
    2007 - 2007
     
  • Functional analysis of Munc18c/Syntaxin4 interactions
    BBSRC
    2005 - 2008
     
  • The role of Rab 11-FIP3 and Rab 11-FIP4 in cytokinesis
    BBSRC
    2005 - 2009
     
  • The role of arfophilins in cytokinesis
    Wellcome Trust
    2004 - 2007
     
  • Functional analysis of the adipocyte secreted proteome
    BBSRC
    2004 - 2007
     
  • Compartmentalisation of insulin signalling in human adipocytes - role of raft associated structures
    Scottish Executive Health Department
    2003 - 2007
     
  • The role of synaptotagmins in GLUT4 translocation in the adipocyte
    Diabetes Research & Wellness Foundation
    2003 - 2006
     
  • The role of synaptotoagmins in GLUT4 translocation in the adipocyte Dr S Miller
    MRC
    2003 - 2006
     
  • Subcellular compartmentalisation analysis by confocal microscopy
    BBSRC
    2003 - 2007
     
  • Lipid rafts and the spatial control of exocytosis
    BBSRC
    2002 - 2005
     
  • Role of Arf5 and Arf6 in regulated membrane trafficking in adipose cells
    BBSRC
    2000 - 2005
     

Additional information

Editorial Board

  • 2005 - 2010: Biochemical Journal
  • 2004 - 2010: Endocrinology
  • 1995 - 1998: Biochemica et Biophysica Acta
  • 1992 - 1997: Biochemical Journal

Grant Advisory Board

  • 2009 - ongoing: Qatar Medical Research Foundation
  • 2004 - 2004: Scottish Executive - Director of Chief Scientists Office Sub-Committee to Review Translational Diabetes Research in Scotland
  • 2002 - 2003: Scottish Executive - Chief Scientists Office Committee to Review Needs of Diabetes Research in Scotland
  • 2002 - 2002: BBSRC - Chair, Sequencing Needs Review Panel
  • 2001 - 2004: BBSRC - Strategy Board
  • 1999 - 1999: Diabetes UK - Studentship & Fellowship Committee
  • 1999 - 2004: BBSRC - Biochemistry & Cell Biology Committee Member, Chairman 2001-04

Invited International Presentations

  • 2010: Oxford, UK - Co-organiser, ?Cell Organization through the Cell Cycle.? British Society of Cell Biology satellite meeting.
  • 2009: Vienna, Austria - Invited Speaker, European Association for the Study of Diabetes Conference,
  • 2009: Glasgow, UK - Invited Speaker, CR-UK Beaton Meetin ?Vesicle Trafficking in Cancer?
  • 2009: Colorado, USA - Invited speaker, FASEB 8th Glucose Transporter Biology,
  • 2009: Oxford, UK - Invited speaker ?Cell Organization through the Cell Cycle.? British Society of Cell Biology satellite meeting.
  • 2008: Edinburgh, UK - Co-organiser, ?Mechanics and Control of Cytokinesis meeting?
  • 2007: Il Ciocco, Italy - FASEB Summer Research Conference on Arf GTPases
  • 2007: Colorado, USA - FASEB Summer Research Conference on Glucose Transporter Biology
  • 2005: Biosciences 2005 - Keynote Speaker
  • 2004: Vermont, USA. - American Society for Cell Biology Satellite Symposium, Cytokinesis
  • 2003: Glasgow Cell Biology Inaugural Meeting
  • 2003: Glasgow, UK. - Society for Experimental Biology
  • 2002: San Francisco, USA. - American Society for Cell Biology
  • 2002: Heidelberg, Germany. - EMBL Predoctoral Student Symposium
  • 2001: Colorado, USA. - FASEB Meeting, Glucose transporter biology.
  • 2001: American Diabetes Association
  • 2001: Diabetes UK

Professional Learned Society

  • 2005 - ongoing: Biochemical Society - Member
  • 2005 - ongoing: American Endocrine Society - Member
  • 2004 - ongoing: American Society of Biochemistry and Molecular Biology - Member
  • 2002 - ongoing: British Cell Biology Society - Regular Member
  • 1999 - ongoing: American Society of Cell Biology - Regular Member
  • 1998 - ongoing: Lister Institute of Preventive Medicine
  • 1992 - ongoing: American Diabetes Association

Research Fellowship

  • 2004 - 2007: Wellcome Trust Research Leave Fellowship
  • 1992 - 1998: Lister Institute Fellowship

Publications

List by: Type | Date

Jump to: 2014 | 2013 | 2012 | 2011 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000
Number of items: 48.

2014

Bhutta, M. S., Roy, B., Gould, G. W., and McInerny, C. J. (2014) A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe. PLoS ONE, 9 (10). e111789. ISSN 1932-6203 (doi:10.1371/journal.pone.0111789)

Kioumourtzoglou, D., Gould, G. W., and Bryant, N. J. (2014) Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism. Molecular and Cellular Biology, 34 (7). pp. 1271-1279. ISSN 0270-7306 (doi:10.1128/MCB.01203-13)

Kioumourtzoglou, D., Sadler, J. B.A., Black, H. L., Berends, R., Wellburn, C., Bryant, N. J., and Gould, G. W. (2014) Studies of the regulated assembly of SNARE complexes in adipocytes. Biochemical Society Transactions, 42 (5). pp. 1396-1400. ISSN 0300-5127 (doi:10.1042/BST20140114)

2013

Neto, H., Kaupisch, A., Collins, L.L., and Gould, G.W. (2013) Syntaxin 16 is a master recruitment factor for cytokinesis. Molecular Biology of the Cell, 24 (23). pp. 3663-3674. ISSN 1059-1524 (doi:10.1091/mbc.E13-06-0302)

Roccisana, J., Sadler, J.B.A., Bryant, N.J., and Gould, G.W. (2013) Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45. Molecular Biology of the Cell, 24 (15). pp. 2389-97. ISSN 1059-1524 (doi:10.1091/mbc.E13-01-0011)

Sadler, J.B., Bryant, N.J., Gould, G.W., and Welburn, C.R. (2013) Posttranslational modifications of GLUT4 affect its subcellular localization and translocation. International Journal of Molecular Sciences, 14 (5). pp. 9963-9978. ISSN 1422-0067 (doi:10.3390/ijms14059963)

2012

Cunningham, M. R., McIntosh, K. A., Pediani, J. D., Robben, J., Cooke, A. E., Nilsson, M., Gould, G. W., Mundell, S., Milligan, G., and Plevin, R. (2012) Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4). Journal of Biological Chemistry, 287 (20). pp. 16656-16669. ISSN 0021-9258 (doi:10.1074/jbc.M111.315911)

Collins, L.L., Simon, G., Matheson, J., Wu, C., Miller, M.C., Otani, T., Yu, X., Hayashi, S., Prekeris, R., and Gould, G.W. (2012) Rab11-FIP3 is a cell cycle-regulated phosphoprotein. BMC Cell Biology, 13 (1). p. 4. ISSN 1471-2121 (doi:10.1186/1471-2121-13-4)

2011

Aran, V., Bryant, N.J., and Gould, G.W. (2011) Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4. BMC Biochemistry, 12 (19). (doi:10.1186/1471-2091-12-19)

Bryant, N.J., and Gould, G.W. (2011) SNARE proteins underpin insulin-regulated GLUT4 traffic. Traffic, 12 (6). pp. 657-664. ISSN 1398-9219 (doi:10.1111/j.1600-0854.2011.01163.x)

Gould, G.W. (2011) IKK : A Kinase at the Intersection of Signaling and Membrane Traffic. Science Signaling, 4 (177). pe30. ISSN 1945-0877 (doi:10.1126/scisignal.2002186)

Neto, H., Collins, L.L., and Gould, G.W. (2011) Vesicle trafficking and membrane remodelling in cytokinesis. Biochemical Journal, 437 (1). pp. 13-24. ISSN 0264-6021 (doi:10.1042/BJ20110153)

Neto, H., and Gould, G.W. (2011) The regulation of abscission by multi-protein complexes. Journal of Cell Science, 124 (19). pp. 3199-3207. ISSN 0021-9533 (doi:10.1242/jcs.083949)

2009

Gould, G.W., and Lippincott-Schwartz, J. (2009) New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nature Reviews Molecular Cell Biology, 10 (4). pp. 287-292. ISSN 1471-0072 (doi:10.1038/nrm2652)

Aran-Ponte, V., Brandie, F.M., Boyd, A.R., Kantidakis, T., Rideout, E.J., Kelly, S.M., Gould, G.W., and Bryant, N.J. (2009) Characterization of two distinct binding modes between syntaxin 4 and Munc18c. Biochemical Journal, 419 (Pt3 ). pp. 655-660. ISSN 0264-6021 (doi:10.1042/BJ20082293)

2008

Simon, G.C., Schonteich, E., Wu, C.C., Piekny, A., Ekiert, D., Yu, X., Gould, G.W., Glotzer, M., and Prekeris, R. (2008) Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis. EMBO Journal, 27 (13). pp. 1791-1803. ISSN 0261-4189 (doi:10.1038/emboj.2008.112)

Brandie, F.M., Aran-Ponte, V., Verma, A., McNew, J.A., Bryant, N.J., and Gould, G.W. (2008) Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c In Vitro. PLoS ONE, 3 (12). e4074. ISSN 1932-6203 (doi:10.1371/journal.pone.0004074)

Prekeris, R., and Gould, G.W. (2008) Breaking up is hard to do - membrane traffic in cytokinesis. Journal of Cell Science, 121 (10). pp. 1569-1576. ISSN 0021-9533 (doi:10.1242/jcs.018770)

2007

Yu, X., Prekeris, R., and Gould, G. (2007) Role of endosomal Rab GTPases in cytokinesis. European Journal of Cell Biology, 86 . pp. 25-35. (doi:10.1016/j.ejcb.2006.10.002)

2006

Choudhury, A., Marks, D., Proctor, K., Gould, G., and Pagano, R. (2006) Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface. Nature Cell Biology, 8 . 317-U6. (doi:10.1038/ncb1380)

Clarke, M., Ewart, M.A., Santy, L.C., Prekeris, R., and Gould, G.W. (2006) ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway. Biochemical and Biophysical Research Communications, 342 . pp. 1361-1367. ISSN 0006-291X (doi:10.1016/j.bbrc.2006.02.102)

Proctor, K., Miller, S., Bryant, N., and Gould, G. (2006) Syntaxin 16 controls the intracellular sequestration of GLUT4 in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications, 347 . pp. 433-438. ISSN 0006-291X (doi:10.1016/j.bbrc.2006.06.135)

2005

Collison, M., James, D., Graham, D., Holman, G., Connell, J., Dominiczak, A.F., Gould, G., and Salt, I. (2005) Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats. Diabetologia, 48 (3). pp. 539-546. ISSN 0012-186X (doi:10.1007/s00125-005-1674-x)

Ewart, M.-A., Clarke, M., Kane, S., Chamberlain, L.H., and Gould, G.W. (2005) Evidence for a role of the exocyst in insulin-stimulated Glut4 trafficking in 3T3-L1 adipocytes. Journal of Biological Chemistry, 280 . pp. 3812-3816. ISSN 0021-9258 (doi:10.1074/jbc.M409928200)

Fielding, A.B., Schonteich, E., Matheson, J., Wilson, G., Yu, X.Z., Hickson, G.R.X., Srivastava, S., Baldwin, S.A., Prekeris, R., and Gould, G.W. (2005) Rab11-FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis. EMBO Journal, 24 . pp. 3389-3399. ISSN 0261-4189 (doi:10.1038/sj.emboj.7600803)

Matheson, J., Yu, X., Fielding, A., and Gould, G. (2005) Membrane traffic in cytokinesis. Biochemical Society Transactions, 33 . pp. 1290-1294.

McGettigan, J. et al. (2005) Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection. Insect Biochemistry and Molecular Biology, 35 . pp. 741-754. (doi:10.1016/j.ibmb.2005.02.017)

Salaun, C., Gould, G., and Chamberlain, L. (2005) Lipid raft association of SNARE proteins regulates exocytosis in PC12 cells. Journal of Biological Chemistry, 280 . pp. 19449-19453. ISSN 0021-9258 (doi:10.1074/jbc.M501923200)

Salaun, C., Gould, G., and Chamberlain, L. (2005) The SNARE proteins SNAP-25 and SNAP-23 display different affinities for lipid rafts in PC12 cells - Regulation by distinct cysteine-rich domains. Journal of Biological Chemistry, 280 . pp. 1236-1240. ISSN 0021-9258 (doi:10.1074/jbc.M410674200)

Tsuboi, T., Ravier, M.A., Xie, H., Ewart, M.-A., Gould, G.W., Baldwin, S.A., and Rutter, G.A. (2005) Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis. Journal of Biological Chemistry, 280 (27). pp. 25565-25570. ISSN 0021-9258 (doi:10.1074/jbc.M501674200)

Wilson, G., Fielding, A., Simon, G., Yu, X., Andrews, P., Hames, R., Frey, A., Peden, A., Gould, G., and Prekeris, R. (2005) The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Molecular Biology of the Cell, 16 . pp. 849-860.

2004

Litherland, G., Hajduch, E., Gould, G., and Hundal, H. (2004) Fructose transport and metabolism in adipose tissue of Zucker rats: Diminished GLUT5 activity during obesity and insulin resistance. Molecular and Cellular Biochemistry, 261 . pp. 23-33.

2003

Hickson, G., Matheson, J., Riggs, B., Maier, V., Fielding, A., Prekeris, R., Sullivan, W., Barr, F., and Gould, G. (2003) Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout. Molecular Biology of the Cell, 14 . pp. 2908-2920. (doi:10.1091/mbc.E03-03-0160)

Morrow, V., Foufelle, F., Connell, J., Petrie, J., Gould, G., and Salt, I. (2003) Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells. Journal of Biological Chemistry, 278 (34). pp. 31629-31639. ISSN 0021-9258 (doi:10.1074/jbc.M212831200)

Perera, H., Clarke, M., Morris, N., Hong, W., Chamberlain, L., and Gould, G. (2003) Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes. Molecular Biology of the Cell, 14 . pp. 2946-2958. (doi:10.1091/mbc.E02-11-0722)

Perry, C., Palmer, T., Cleland, S., Morton, I., Salt, I., Petrie, J., Gould, G., and Connell, J. (2003) Decreased insulin sensitivity during dietary sodium restriction is not mediated by effects of angiotensin II on insulin action. Clinical Science, 105 (2). pp. 187-194. ISSN 0143-5221 (doi:10.1042/CS20020320)

Riggs, B., Rothwell, W., Mische, S., Hickson, G., Matheson, J., Hays, T., Gould, G., and Sullivan, W. (2003) Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and RAb11. Journal of Cell Biology, 163 . pp. 143-154. (doi:10.1083/jcb.200305115)

2002

Chamberlain, L., and Gould, G. (2002) The vesicle- and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes. Journal of Biological Chemistry, 277 . pp. 49750-49754. ISSN 0021-9258 (doi:10.1074/jbc.M206936200)

Kelly, C.J.G., Lyall, H., Petrie, J.R., Gould, G.W., Connell, J.M.C., Rumley, A., Lowe, G.D.O., and Sattar, N. (2002) A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism, 87 (7). pp. 3287-3290. ISSN 0021-972X (doi:10.1210/jc.87.7.3287)

Kelly, C., Speirs, A., Gould, G., Petrie, J., Lyall, H., and Connell, J. (2002) Altered vascular function in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 87 (2). pp. 742-746. ISSN 0021-972X (doi:10.1210/jc.87.2.742)

2001

Chamberlain, L., Burgoyne, R., and Gould, G. (2001) SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis. Proceedings of the National Academy of Sciences of the United States of America, 98 (10). pp. 5619-5624. ISSN 0027-8424 (doi: 10.1073/pnas.091502398)

Chamberlain, L., Graham, M., Kane, S., Jackson, J., Maier, V., Burgoyne, R., and Gould, G. (2001) The synaptic vesicle protein, cysteine-string protein, is associated with the plasma membrane in 3T3-L1 adipocytes and interacts with syntaxin 4. Journal of Cell Science, 114 . pp. 445-455.

James, D.J., Cairns, F., Salt, I.P., Murphy, G.J., Dominiczak, A.F., Connell, J.M.C., and Gould, G.W. (2001) Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin. Diabetes, 50 (9). pp. 2148-2156. ISSN 0012-1797 (doi:10.2337/diabetes.50.9.2148 )

Kelly, C., Lyall, H., Petrie, J., Gould, G., Connell, J., and Sattar, N. (2001) Low grade chronic inflammation in women with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism, 86 (6). pp. 2453-2455. ISSN 0021-972X (doi:10.1210/jc.86.6.2453)

MacKenzie, C.J., Wakefield, J.M., Cairns, F., Dominiczak, A.F., and Gould, G.W. (2001) Regulation of glucose transport in aortic smooth muscle cells by cAMP and cGMP. Biochemical Journal, 353 . pp. 513-519. ISSN 0264-6021

Petrie, J., Collison, M., Connell, J., Gould, G., and Dominiczak, A. (2001) CD36 deficiency and insulin resistance. Lancet, 358 (9277). pp. 242-243. ISSN 0140-6736 (doi:10.1016/S0140-6736(01)05428-9)

2000

Collison, M., Campbell, I., Salt, I., Dominiczak, A., Connell, J., Lyall, H., and Gould, G. (2000) Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins. Diabetologia, 43 (11). pp. 1374-1380. ISSN 0012-186X (doi:10.1007/s001250051541)

Salt, I., Connell, J., and Gould, G. (2000) 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes, 49 (10). pp. 1649-1656. ISSN 0012-1797 (doi:10.2337/diabetes.49.10.1649)

This list was generated on Sat Nov 22 23:58:58 2014 GMT.
Jump to: Articles
Number of items: 48.

Articles

Bhutta, M. S., Roy, B., Gould, G. W., and McInerny, C. J. (2014) A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe. PLoS ONE, 9 (10). e111789. ISSN 1932-6203 (doi:10.1371/journal.pone.0111789)

Kioumourtzoglou, D., Gould, G. W., and Bryant, N. J. (2014) Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism. Molecular and Cellular Biology, 34 (7). pp. 1271-1279. ISSN 0270-7306 (doi:10.1128/MCB.01203-13)

Kioumourtzoglou, D., Sadler, J. B.A., Black, H. L., Berends, R., Wellburn, C., Bryant, N. J., and Gould, G. W. (2014) Studies of the regulated assembly of SNARE complexes in adipocytes. Biochemical Society Transactions, 42 (5). pp. 1396-1400. ISSN 0300-5127 (doi:10.1042/BST20140114)

Neto, H., Kaupisch, A., Collins, L.L., and Gould, G.W. (2013) Syntaxin 16 is a master recruitment factor for cytokinesis. Molecular Biology of the Cell, 24 (23). pp. 3663-3674. ISSN 1059-1524 (doi:10.1091/mbc.E13-06-0302)

Roccisana, J., Sadler, J.B.A., Bryant, N.J., and Gould, G.W. (2013) Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45. Molecular Biology of the Cell, 24 (15). pp. 2389-97. ISSN 1059-1524 (doi:10.1091/mbc.E13-01-0011)

Sadler, J.B., Bryant, N.J., Gould, G.W., and Welburn, C.R. (2013) Posttranslational modifications of GLUT4 affect its subcellular localization and translocation. International Journal of Molecular Sciences, 14 (5). pp. 9963-9978. ISSN 1422-0067 (doi:10.3390/ijms14059963)

Cunningham, M. R., McIntosh, K. A., Pediani, J. D., Robben, J., Cooke, A. E., Nilsson, M., Gould, G. W., Mundell, S., Milligan, G., and Plevin, R. (2012) Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4). Journal of Biological Chemistry, 287 (20). pp. 16656-16669. ISSN 0021-9258 (doi:10.1074/jbc.M111.315911)

Collins, L.L., Simon, G., Matheson, J., Wu, C., Miller, M.C., Otani, T., Yu, X., Hayashi, S., Prekeris, R., and Gould, G.W. (2012) Rab11-FIP3 is a cell cycle-regulated phosphoprotein. BMC Cell Biology, 13 (1). p. 4. ISSN 1471-2121 (doi:10.1186/1471-2121-13-4)

Aran, V., Bryant, N.J., and Gould, G.W. (2011) Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4. BMC Biochemistry, 12 (19). (doi:10.1186/1471-2091-12-19)

Bryant, N.J., and Gould, G.W. (2011) SNARE proteins underpin insulin-regulated GLUT4 traffic. Traffic, 12 (6). pp. 657-664. ISSN 1398-9219 (doi:10.1111/j.1600-0854.2011.01163.x)

Gould, G.W. (2011) IKK : A Kinase at the Intersection of Signaling and Membrane Traffic. Science Signaling, 4 (177). pe30. ISSN 1945-0877 (doi:10.1126/scisignal.2002186)

Neto, H., Collins, L.L., and Gould, G.W. (2011) Vesicle trafficking and membrane remodelling in cytokinesis. Biochemical Journal, 437 (1). pp. 13-24. ISSN 0264-6021 (doi:10.1042/BJ20110153)

Neto, H., and Gould, G.W. (2011) The regulation of abscission by multi-protein complexes. Journal of Cell Science, 124 (19). pp. 3199-3207. ISSN 0021-9533 (doi:10.1242/jcs.083949)

Gould, G.W., and Lippincott-Schwartz, J. (2009) New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nature Reviews Molecular Cell Biology, 10 (4). pp. 287-292. ISSN 1471-0072 (doi:10.1038/nrm2652)

Aran-Ponte, V., Brandie, F.M., Boyd, A.R., Kantidakis, T., Rideout, E.J., Kelly, S.M., Gould, G.W., and Bryant, N.J. (2009) Characterization of two distinct binding modes between syntaxin 4 and Munc18c. Biochemical Journal, 419 (Pt3 ). pp. 655-660. ISSN 0264-6021 (doi:10.1042/BJ20082293)

Simon, G.C., Schonteich, E., Wu, C.C., Piekny, A., Ekiert, D., Yu, X., Gould, G.W., Glotzer, M., and Prekeris, R. (2008) Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis. EMBO Journal, 27 (13). pp. 1791-1803. ISSN 0261-4189 (doi:10.1038/emboj.2008.112)

Brandie, F.M., Aran-Ponte, V., Verma, A., McNew, J.A., Bryant, N.J., and Gould, G.W. (2008) Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c In Vitro. PLoS ONE, 3 (12). e4074. ISSN 1932-6203 (doi:10.1371/journal.pone.0004074)

Prekeris, R., and Gould, G.W. (2008) Breaking up is hard to do - membrane traffic in cytokinesis. Journal of Cell Science, 121 (10). pp. 1569-1576. ISSN 0021-9533 (doi:10.1242/jcs.018770)

Yu, X., Prekeris, R., and Gould, G. (2007) Role of endosomal Rab GTPases in cytokinesis. European Journal of Cell Biology, 86 . pp. 25-35. (doi:10.1016/j.ejcb.2006.10.002)

Choudhury, A., Marks, D., Proctor, K., Gould, G., and Pagano, R. (2006) Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface. Nature Cell Biology, 8 . 317-U6. (doi:10.1038/ncb1380)

Clarke, M., Ewart, M.A., Santy, L.C., Prekeris, R., and Gould, G.W. (2006) ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway. Biochemical and Biophysical Research Communications, 342 . pp. 1361-1367. ISSN 0006-291X (doi:10.1016/j.bbrc.2006.02.102)

Proctor, K., Miller, S., Bryant, N., and Gould, G. (2006) Syntaxin 16 controls the intracellular sequestration of GLUT4 in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications, 347 . pp. 433-438. ISSN 0006-291X (doi:10.1016/j.bbrc.2006.06.135)

Collison, M., James, D., Graham, D., Holman, G., Connell, J., Dominiczak, A.F., Gould, G., and Salt, I. (2005) Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats. Diabetologia, 48 (3). pp. 539-546. ISSN 0012-186X (doi:10.1007/s00125-005-1674-x)

Ewart, M.-A., Clarke, M., Kane, S., Chamberlain, L.H., and Gould, G.W. (2005) Evidence for a role of the exocyst in insulin-stimulated Glut4 trafficking in 3T3-L1 adipocytes. Journal of Biological Chemistry, 280 . pp. 3812-3816. ISSN 0021-9258 (doi:10.1074/jbc.M409928200)

Fielding, A.B., Schonteich, E., Matheson, J., Wilson, G., Yu, X.Z., Hickson, G.R.X., Srivastava, S., Baldwin, S.A., Prekeris, R., and Gould, G.W. (2005) Rab11-FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis. EMBO Journal, 24 . pp. 3389-3399. ISSN 0261-4189 (doi:10.1038/sj.emboj.7600803)

Matheson, J., Yu, X., Fielding, A., and Gould, G. (2005) Membrane traffic in cytokinesis. Biochemical Society Transactions, 33 . pp. 1290-1294.

McGettigan, J. et al. (2005) Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection. Insect Biochemistry and Molecular Biology, 35 . pp. 741-754. (doi:10.1016/j.ibmb.2005.02.017)

Salaun, C., Gould, G., and Chamberlain, L. (2005) Lipid raft association of SNARE proteins regulates exocytosis in PC12 cells. Journal of Biological Chemistry, 280 . pp. 19449-19453. ISSN 0021-9258 (doi:10.1074/jbc.M501923200)

Salaun, C., Gould, G., and Chamberlain, L. (2005) The SNARE proteins SNAP-25 and SNAP-23 display different affinities for lipid rafts in PC12 cells - Regulation by distinct cysteine-rich domains. Journal of Biological Chemistry, 280 . pp. 1236-1240. ISSN 0021-9258 (doi:10.1074/jbc.M410674200)

Tsuboi, T., Ravier, M.A., Xie, H., Ewart, M.-A., Gould, G.W., Baldwin, S.A., and Rutter, G.A. (2005) Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis. Journal of Biological Chemistry, 280 (27). pp. 25565-25570. ISSN 0021-9258 (doi:10.1074/jbc.M501674200)

Wilson, G., Fielding, A., Simon, G., Yu, X., Andrews, P., Hames, R., Frey, A., Peden, A., Gould, G., and Prekeris, R. (2005) The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Molecular Biology of the Cell, 16 . pp. 849-860.

Litherland, G., Hajduch, E., Gould, G., and Hundal, H. (2004) Fructose transport and metabolism in adipose tissue of Zucker rats: Diminished GLUT5 activity during obesity and insulin resistance. Molecular and Cellular Biochemistry, 261 . pp. 23-33.

Hickson, G., Matheson, J., Riggs, B., Maier, V., Fielding, A., Prekeris, R., Sullivan, W., Barr, F., and Gould, G. (2003) Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout. Molecular Biology of the Cell, 14 . pp. 2908-2920. (doi:10.1091/mbc.E03-03-0160)

Morrow, V., Foufelle, F., Connell, J., Petrie, J., Gould, G., and Salt, I. (2003) Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells. Journal of Biological Chemistry, 278 (34). pp. 31629-31639. ISSN 0021-9258 (doi:10.1074/jbc.M212831200)

Perera, H., Clarke, M., Morris, N., Hong, W., Chamberlain, L., and Gould, G. (2003) Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes. Molecular Biology of the Cell, 14 . pp. 2946-2958. (doi:10.1091/mbc.E02-11-0722)

Perry, C., Palmer, T., Cleland, S., Morton, I., Salt, I., Petrie, J., Gould, G., and Connell, J. (2003) Decreased insulin sensitivity during dietary sodium restriction is not mediated by effects of angiotensin II on insulin action. Clinical Science, 105 (2). pp. 187-194. ISSN 0143-5221 (doi:10.1042/CS20020320)

Riggs, B., Rothwell, W., Mische, S., Hickson, G., Matheson, J., Hays, T., Gould, G., and Sullivan, W. (2003) Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and RAb11. Journal of Cell Biology, 163 . pp. 143-154. (doi:10.1083/jcb.200305115)

Chamberlain, L., and Gould, G. (2002) The vesicle- and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes. Journal of Biological Chemistry, 277 . pp. 49750-49754. ISSN 0021-9258 (doi:10.1074/jbc.M206936200)

Kelly, C.J.G., Lyall, H., Petrie, J.R., Gould, G.W., Connell, J.M.C., Rumley, A., Lowe, G.D.O., and Sattar, N. (2002) A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism, 87 (7). pp. 3287-3290. ISSN 0021-972X (doi:10.1210/jc.87.7.3287)

Kelly, C., Speirs, A., Gould, G., Petrie, J., Lyall, H., and Connell, J. (2002) Altered vascular function in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 87 (2). pp. 742-746. ISSN 0021-972X (doi:10.1210/jc.87.2.742)

Chamberlain, L., Burgoyne, R., and Gould, G. (2001) SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis. Proceedings of the National Academy of Sciences of the United States of America, 98 (10). pp. 5619-5624. ISSN 0027-8424 (doi: 10.1073/pnas.091502398)

Chamberlain, L., Graham, M., Kane, S., Jackson, J., Maier, V., Burgoyne, R., and Gould, G. (2001) The synaptic vesicle protein, cysteine-string protein, is associated with the plasma membrane in 3T3-L1 adipocytes and interacts with syntaxin 4. Journal of Cell Science, 114 . pp. 445-455.

James, D.J., Cairns, F., Salt, I.P., Murphy, G.J., Dominiczak, A.F., Connell, J.M.C., and Gould, G.W. (2001) Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin. Diabetes, 50 (9). pp. 2148-2156. ISSN 0012-1797 (doi:10.2337/diabetes.50.9.2148 )

Kelly, C., Lyall, H., Petrie, J., Gould, G., Connell, J., and Sattar, N. (2001) Low grade chronic inflammation in women with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism, 86 (6). pp. 2453-2455. ISSN 0021-972X (doi:10.1210/jc.86.6.2453)

MacKenzie, C.J., Wakefield, J.M., Cairns, F., Dominiczak, A.F., and Gould, G.W. (2001) Regulation of glucose transport in aortic smooth muscle cells by cAMP and cGMP. Biochemical Journal, 353 . pp. 513-519. ISSN 0264-6021

Petrie, J., Collison, M., Connell, J., Gould, G., and Dominiczak, A. (2001) CD36 deficiency and insulin resistance. Lancet, 358 (9277). pp. 242-243. ISSN 0140-6736 (doi:10.1016/S0140-6736(01)05428-9)

Collison, M., Campbell, I., Salt, I., Dominiczak, A., Connell, J., Lyall, H., and Gould, G. (2000) Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins. Diabetologia, 43 (11). pp. 1374-1380. ISSN 0012-186X (doi:10.1007/s001250051541)

Salt, I., Connell, J., and Gould, G. (2000) 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes, 49 (10). pp. 1649-1656. ISSN 0012-1797 (doi:10.2337/diabetes.49.10.1649)

This list was generated on Sat Nov 22 23:58:58 2014 GMT.