Glasgow Orthopaedic Research Centre
Founded in 2009 through discussion between Mr Dominic Meek and Dr Matt Dalby, the Glasgow Orthopaedic Research Initiative (GLORI) has been established to encourage collaboration between the basic sciences, applied sciences, engineering and clinic. This has the aim of bringing the latest ideas in basic materials research into use to deliver the next-generation of orthopaedic care. It combines expertise from orthopaedic surgeons, biologists, engineers and chemists from Glasgow and Strathclyde Universities.
Past GLORI Meetings:
6th May 2010
22nd October 2012
Examples of direct GLORI funding:
Ms Sarah Maclaine (registrar surgeon) is undertaking a Scottish Health Executive Funded project on generating living impaction graft in vitro using nanoscaffolds.
Dr Laura McNamara (postdoctoral scientist) is undertaking an EPSRC funded project on developing nanostructured titanium materials for bone regeneration.
Mr R.M. Dominic Meek FRCS, MD, Consultant, in Orthopaedics and Trauma Surgery, Southern General Hospital, Glasgow and Honorary Senior Lecturer at the University of Glasgow. He undertook a fellowship in adult reconstruction of the hip and knee at the department of lower limb arthroplasty, Vancouver General Hospital. He was awarded the British and American Hip Societies Travelling Fellow in 2005 and the ABC Fellowship in 2008. His research interests are in the basic science of wear particles particularly metal CoCr particles and implant fixation and bone regeneration. Member of BOA,BHS and BORS.
Dr Matt Dalby, PhD, became a Lecturer in Cell Engineering at the University of Glasgow after completing a BBSRC David Phillips Fellowship. His research interests are osteogenesis and cellular mechanotransduction. Further information on awards, grants and publications at: http://www.gla.ac.uk:443/ibls/staff/staff.php?who=PGn|Pe
Mr David Allan, FRCS, Consultant in Orthopaedic Surgery, Southern General Hospital, Glasgow. He specialised in spinal injuries and is clinical director of the Scottish Centre for Innovation in Spinal Cord Injury (SCISCI). For more information, please visit: http://www.gla.ac.uk/departments/scisci/
Mr Alistair Brydone is a specialist registrar in orthopaedic surgery. He is developing research interests with a focus in wound healing and new technologies for improving implant design. He is currently clinically active at the Southern General Hospital and pursues his basic research in the Centre for Cell Engineering.
Maggie Cusack, Professor of Biomineralisation at the University of Glasgow. Her research focusses mainly on invertebrate biominerals. She aims to cross the bone-shell divide between calcium phosphate of vertebrate bone and calcium carbonate of invertebrate shells in order to understand and exploit osteo-induction by nacre (mother of pearl). For more information, please visit http://www.ges.gla.ac.uk:443/staff/mcusack
Dr Nikolaj Gadegaard, PhD, became a Lecturer in Bioengineering at the University of Glasgow after completing a Royal Society of Edinburgh Personal Fellowship. He specialises in micro and nanoscale surfaces and further information can be found at: http://userweb.elec.gla.ac.uk/n/nikolaj/
Prof M. Helen Grant, PhD, is Professor of Bioengineering at the University of Strathclyde. Her interests are in liver and bone tissue engineering and metal toxicology. Further information can be found at: http://www.strath.ac.uk/bioeng/staff/grantmhelenprof/
Mr Jim Huntley MA DPhil (Oxon) FRCS is Consultant in Paediatric Orthopaedics and trauma at the Royal Hospital for Sick Children, Yorkhill, Glasgow. He undertook a paediatric orthopaedic and trauma fellowship at the Starship, New Zealand (07-08), and was subsequently awarded the 2009 BORS-ORS travelling fellowship. His research interests are in articular cartilage (biology and repair), growth plate and morphogenesis, infection and paediatric trauma. He is a member of BORS, BSCOS, BOA, and ASGBI. He is also Associate Editor (Science) for the Scottish Medical Journal. Department synopsis/contact details http://www.yorkhill.wscotorth.org.uk/secure/info/RHSC%20Trainer%20CVs.pdf
Prof Iain McInnes, MRCP, PhD, is a rheumatologist and Professor of Experimental Medicine and Rheumatology at the University of Glasgow. His major interests are in the biology of inflammatory synovitis in rheumatoid arthritis, psoriatic arthritis and septic arthritis. Further information can be found at: http://www.gla.ac.uk/departments/immunology/researchgroups/iainmcinnes/research/#d.en.55112
Mr Neal Millar is an arc Orthopaedic Clinical Research Fellow. He is an SpR on the West of Scotland scheme, investigating inflammation in tendon disease and actively welcomes collaboration with Orthopaedic Surgeons/Trainees in the West of Scotland. Details of the Division are available at http://www.gla.ac.uk/departments/immunology/
Dr Philip Riches, PhD, is a Lecturer in Bioengineering at the University of Strathlyde. His research interests are in spinal biomechanics. In particular, mechanical property determination of intervertebral disc tissue, mathematical modelling of soft tissue, and spinal motion during exercise. Further information can be found at: http://www.strath.ac.uk/bioeng/staff/richesphilipdr/
Dr Mathis Riehle, PhD, is a Reader in Cell Engineering at the University of Glasgow. His research interests are in device design for biological systems and durotaxis. Further information can be found at: http://www.gla.ac.uk:443/ibls/staff/staff.php?who=PAnnQ|
Prof K. Elizabeth Tanner, FREng, FBSE, MA, DPhil, FIMechE, FIMMM, CEng, CSci, is Professor of Mechanics of Materials and Structures at the University of Glasgow. Her research interests are in bone composite materials and mechanical properties of materials. Further information can be found at: http://www.mech.gla.ac.uk/ourstaff/vcard.html?PersonID=272.
Prof Rein Ulijn, FRSC, PhD, is WestCHEM Professor of Chemistry at the University of Strathclyde. His research interests include switchable chemistry and enzyme direct self-assembly of 2D and 3D hydrogels. Further information can e found at: http://www.chem.strath.ac.uk/people/academic/rein_ulijn
GLORI also invites honourary members who are world-leaders in their field of orthopaedic research to help with our aims and ambitions. Currently, these are:
Mr Andrew Wilkinson, Registrar Surgeon, undertaking a BOA funded MD on bioactive ceramics.
Mr Alistair Brydone, Registrar Surgeon, undertaking a Golden Jubilee/InVibio/EPSRC funded PhD on PEEK
Jingli Yang, PhD student, undertaking and EPSRC funded PhD on bioactive nanopatterns
Louisa Lee, PhD student, who is undertaking an MVLS funded PhD on bioactive nanopatterns
Prof Tim Briggs, FRCS, Professor of Orthopaedic Surgery in the Royal National Orthopaedic Hospital Trust, Stanmore. He is interested in cartilage repair and regeneration or the roles of hydroxyapatite in prosthesis fixation.
Prof Andrew McCaskie, (http://www.ncl.ac.uk/biomedicine/research/groups/profile/a.w.mccaskie), Professor of Orthopaedic Surgery in the Freeman Hospital, Newcastle upon Tyne and a member of the University of Newcastle Biomedicine Research School. He is interested in lower limb arthroplasty and cell adhesion to nanomaterials.
Prof Hamish Simpson, (http://www.crm.ed.ac.uk/), Professor of Orthopaedics and Trauma in the Department of Orthopaedic Surgery at the University of Edinburgh. He is interested in orthopaedic repair using stem cells.
The image next to Prof McInnes is from his review in Nature Reviews Immunology 7, 429-442 (June 2007) with permission NPG.
GLORI: Glasgow Orthopaedic Research Initiative, School of Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
tel: +44 (0)141 330 3550
fax: +44 (0)141 330 2085
email: Matthew.Dalby@glasgow.ac.uk