The ischial tuberosity is covered by gluteus maximus except when the hip is flexed; at this point it can be readily felt.
Because gluteus maximus moves across the outer surface of the tuberosity, a fluid-filled bursa is located between them, to reduce friction. In jobs where there is repetitive backwards and forwards movement of the body when seated, this bursa may become inflamed. In mill towns of Scotland, the condition of "weaver's bottom" was a recognised industrial hazard.