Royal Statistical Society
Statistical Computing Section Meetings
Bioinformatics - Statistical Computing Challenges
Karen Ayres (Reading
)
"Statistical Genetics and Computing - general and specific
considerations"
Synopsis: An overview of statistical genetics will be given first,
highlighting some areas that rely heavily on statistical
computing. More details will then be presented on the
specific problem of estimating human mutation and recombination
rates from DNA sequence data via Markov chain Monte Carlo.
The slides for this talk are available in pdf format.
Pak Sham, Jing-Hua Zhao and Shaun Purcell (Institute of Psychiatry
)
"Modularity and interfacing in statistical software"
Synopsis: We introduce the problems of haplotype frequency
estimation and population substructure detection, and describe
gene-counting algorithms for finding maximum likelihood
estimates. Their performance of these methods will be evaluated
by real or simulated data.
Richard Durbin (Wellcome Trust Sanger Institute
)
"The current state of gene prediction from genome sequence"
Synopsis: The talk will give an overview of the scientific
context and the statistical approaches currently used for
gene prediction.
Date & Time
Wednesday 23 January at 2:00 - 5:00 pm
Place
Errol Street
(nearest UG stations, Barbican, Moorgate & Old Street)
Refreshments
There will be tea and biscuits served between the first and second talks at 3:00 - 3:30 pm.
