Research
The research carried out the in Division of Clinical Neuroscience focusses on the following areas:
- Glial Cell Biology
Glial cell biology research focuses on two aspects of glial cell biology. The first involves the manipulations of oligodendrocytes to facilitate remyelination and the second the study of the potential of a specialised glial cell from the olfactory system, termed olfactory ensheathing cells (OEC) to repair the damaged CNS.
Neuroimmunology
The Neuroimmunology group is concerned with dissecting out the pathogenesis of autoimmune neuropathies, using a wide variety of approaches, techniques and collaborations.- Neurovirology
The main focus of the laboratory for the last 14 years has been on Varicella-zoster virus (VZV) latency in the human nervous system. We also study the possible viral involvement and alteration of myelin gene expression in Multiple Sclerosis.
- Stroke
Stroke research includes the areas of: Basic Stroke Research and Clinical Stroke.
- Trypanosomiasis
The primary focus of the group is to study the pathogenesis of Human African trypanosomiasis (HAT) also known as sleeping sickness which is a major killer throughout sub-Saharan Africa. For the last 20 yrs we have been using a highly reproducible mouse model of the post-reactive treatment encephalopathy (PTRE) which is seen in HAT. Our long term goals are to better understand how the brain disease is caused by the infection and to devise more effective treatment for the disease.